| Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity AP Arruda, BM Pers, G Parlakgül, E Güney, K Inouye, GS Hotamisligil Nature medicine 20 (12), 1427-1435, 2014 | 618 | 2014 |
| Calcium homeostasis and organelle function in the pathogenesis of obesity and diabetes AP Arruda, GS Hotamisligil Cell metabolism 22 (3), 381-397, 2015 | 305 | 2015 |
| Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ... Diabetes 61 (6), 1455-1462, 2012 | 245 | 2012 |
| Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion AP Arruda, M Milanski, A Coope, AS Torsoni, E Ropelle, DP Carvalho, ... Endocrinology 152 (4), 1314-1326, 2011 | 218 | 2011 |
| NRF1 is an ER membrane sensor that is central to cholesterol homeostasis SB Widenmaier, NA Snyder, TB Nguyen, A Arduini, GY Lee, AP Arruda, ... Cell 171 (5), 1094-1109. e15, 2017 | 189 | 2017 |
| Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ... Nature medicine 24 (3), 292-303, 2018 | 165 | 2018 |
| Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity S Fu, A Yalcin, GY Lee, P Li, J Fan, AP Arruda, BM Pers, M Yilmaz, ... Science translational medicine 7 (292), 292ra98-292ra98, 2015 | 109 | 2015 |
| Hypothalamic actions of tumor necrosis factor α provide the thermogenic core for the wastage syndrome in cachexia AP Arruda, M Milanski, T Romanatto, C Solon, A Coope, LC Alberici, ... Endocrinology 151 (2), 683-694, 2010 | 95 | 2010 |
| Role of Sarco/Endoplasmic Reticulum Ca2+-ATPase in Thermogenesis L de Meis, AP Arruda, DP Carvalho Bioscience Reports 25 (3-4), 181-190, 2005 | 90 | 2005 |
| Defective regulation of the ubiquitin/proteasome system in the hypothalamus of obese male mice LM Ignacio-Souza, B Bombassaro, LB Pascoal, MA Portovedo, DS Razolli, ... Endocrinology 155 (8), 2831-2844, 2014 | 71 | 2014 |
| TNF-α transiently induces endoplasmic reticulum stress and an incomplete unfolded protein response in the hypothalamus RG Denis, AP Arruda, T Romanatto, M Milanski, A Coope, C Solon, ... Neuroscience 170 (4), 1035-1044, 2010 | 71 | 2010 |
| The impact of science in Brazil L de Meis, AP Arruda, J Guimarães IUBMB life 59 (4‐5), 227-234, 2007 | 65 | 2007 |
| Identification of a Ca2+-ATPase in brown adipose tissue mitochondria: regulation of thermogenesis by ATP and Ca2+ L de Meis, AP Arruda, RM da Costa, M Benchimol Journal of Biological Chemistry 281 (24), 16384-16390, 2006 | 64 | 2006 |
| Cold Tolerance in Hypothyroid Rabbits: Role of Skeletal Muscle Mitochondria and Sarcoplasmic Reticulum Ca2+ ATPase Isoform 1 Heat Production AP Arruda, LA Ketzer, M Nigro, A Galina, DP Carvalho, L de Meis Endocrinology 149 (12), 6262-6271, 2008 | 62 | 2008 |
| Intercellular transmission of hepatic ER stress in obesity disrupts systemic metabolism A Tirosh, G Tuncman, ES Calay, M Rathaus, I Ron, A Tirosh, A Yalcin, ... Cell metabolism 33 (2), 319-333. e6, 2021 | 59 | 2021 |
| Regulation of liver subcellular architecture controls metabolic homeostasis G Parlakgül, AP Arruda, S Pang, E Cagampan, N Min, E Güney, GY Lee, ... Nature 603 (7902), 736-742, 2022 | 58 | 2022 |
| Hyperthyroidism increases the uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPase AP Arruda, WS Da-Silva, DP Carvalho, L De Meis Biochemical Journal 375 (3), 753-760, 2003 | 58 | 2003 |
| Thermogenic activity of Ca2+-ATPase from skeletal muscle heavy sarcoplasmic reticulum: the role of ryanodine Ca2+ channel AP Arruda, M Nigro, GM Oliveira, L de Meis Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (6), 1498-1505, 2007 | 54 | 2007 |
| Taurine enhances the anorexigenic effects of insulin in the hypothalamus of rats CS Solon, D Franci, LM Ignacio-Souza, T Romanatto, EA Roman, ... Amino acids 42, 2403-2410, 2012 | 48 | 2012 |
| Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity AP Arruda, BM Pers, G Parlakgul, E Güney, T Goh, E Cagampan, GY Lee, ... Elife 6, e29968, 2017 | 47 | 2017 |
Gunes Parlakgul, M.D.Adjunct Assistant Professor, University of California, BerkeleyVerified email at berkeley.edu
