Scott Ayton, PhD
Scott Ayton, PhD
Florey Institute of Neuroscience and Mental Health
Verified email at unimelb.edu.au
TitleCited byYear
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ...
Nature medicine 18 (2), 291, 2012
3682012
Metallostasis in Alzheimer's disease
S Ayton, P Lei, AI Bush
Free Radical Biology and Medicine 62, 76-89, 2013
2482013
A delicate balance: iron metabolism and diseases of the brain
DJ Hare, S Ayton, AI Bush, P Lei
Frontiers in aging neuroscience 5, 34, 2013
2172013
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease
S Ayton, P Lei, JA Duce, BXW Wong, A Sedjahtera, PA Adlard, AI Bush, ...
Annals of neurology 73 (4), 554-559, 2013
1512013
Tau protein: relevance to Parkinson's disease
P Lei, S Ayton, DI Finkelstein, PA Adlard, CL Masters, AI Bush
The international journal of biochemistry & cell biology 42 (11), 1775-1778, 2010
1442010
Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE
S Ayton, NG Faux, AI Bush
Nature communications 6 (1), 1-9, 2015
1232015
GSK-3 in neurodegenerative diseases
P Lei, S Ayton, AI Bush, PA Adlard
International Journal of Alzheimer’s Disease 2011, 2011
1142011
The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease
LW Hung, VL Villemagne, L Cheng, NA Sherratt, S Ayton, AR White, ...
Journal of Experimental Medicine 209 (4), 837-854, 2012
1042012
Nigral iron elevation is an invariable feature of Parkinson’s disease and is a sufficient cause of neurodegeneration
S Ayton, P Lei
BioMed research international 2014, 2014
852014
Biometals and their therapeutic implications in Alzheimer’s disease
S Ayton, P Lei, AI Bush
Neurotherapeutics 12 (1), 109-120, 2015
812015
An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta
DJ Hare, P Lei, S Ayton, BR Roberts, R Grimm, JL George, DP Bishop, ...
Chemical Science 5 (6), 2160-2169, 2014
752014
Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
QZ Tuo, P Lei, KA Jackman, XL Li, H Xiong, ZY Liuyang, L Roisman, ...
Molecular psychiatry 22 (11), 1520-1530, 2017
742017
Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline
S Ayton, A Fazlollahi, P Bourgeat, P Raniga, A Ng, YY Lim, I Diouf, ...
Brain 140 (8), 2112-2119, 2017
692017
Current state of Alzheimer’s fluid biomarkers
JL Molinuevo, S Ayton, R Batrla, MM Bednar, T Bittner, J Cummings, ...
Acta neuropathologica 136 (6), 821-853, 2018
682018
Ferroptosis and cell death mechanisms in Parkinson's disease
SJ Guiney, PA Adlard, AI Bush, DI Finkelstein, S Ayton
Neurochemistry international 104, 34-48, 2017
672017
Motor and cognitive deficits in aged tau knockout mice in two background strains
P Lei, S Ayton, S Moon, Q Zhang, I Volitakis, DI Finkelstein, AI Bush
Molecular neurodegeneration 9 (1), 29, 2014
622014
Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein
S Ayton, P Lei, DJ Hare, JA Duce, JL George, PA Adlard, C McLean, ...
Journal of Neuroscience 35 (8), 3591-3597, 2015
612015
Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases
D Furtado, M Björnmalm, S Ayton, AI Bush, K Kempe, F Caruso
Advanced Materials 30 (46), 1801362, 2018
472018
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse
P Lei, S Ayton, AT Appukuttan, I Volitakis, PA Adlard, DI Finkelstein, ...
Neurobiology of disease 81, 168-175, 2015
472015
Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease
S Ayton, P Lei, PA Adlard, I Volitakis, RA Cherny, AI Bush, DI Finkelstein
Molecular neurodegeneration 9 (1), 27, 2014
432014
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