Dual-target binding ligands with modulated pharmacokinetics for endoradiotherapy of prostate cancer JM Kelly, A Amor-Coarasa, A Nikolopoulou, T Wüstemann, P Barelli, ... Journal of Nuclear Medicine 58 (9), 1442-1449, 2017 | 72 | 2017 |
The application of vinylogous iminium salt derivatives to efficient formal syntheses of the marine alkaloids lamellarin G trimethyl ether and ningalin B JT Gupton, BC Giglio, JE Eaton, EA Rieck, KL Smith, MJ Keough, ... Tetrahedron 65 (22), 4283-4292, 2009 | 50 | 2009 |
Pyrrole-based antitubulin agents: two distinct binding modalities are predicted for C-2 analogues in the colchicine site C Da, N Telang, P Barelli, X Jia, JT Gupton, SL Mooberry, GE Kellogg ACS medicinal chemistry letters 3 (1), 53-57, 2012 | 25 | 2012 |
The application of (Z)-3-aryl-3-haloenoic acids to the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2 (5H)-ones JT Gupton, N Telang, EJ Banner, EJ Kluball, KE Hall, KL Finzel, X Jia, ... Tetrahedron 66 (47), 9113-9122, 2010 | 21 | 2010 |
Developing novel C-4 analogues of pyrrole-based antitubulin agents: weak but critical hydrogen bonding in the colchicine site C Da, N Telang, K Hall, E Kluball, P Barelli, K Finzel, X Jia, JT Gupton, ... MedChemComm 4 (2), 417-421, 2013 | 20 | 2013 |
Preparation of indole containing building blocks for the regiospecific construction of indole appended pyrazoles and pyrroles JT Gupton, N Telang, DF Gazzo, PJ Barelli, KE Lescalleet, JW Fagan, ... Tetrahedron 69 (29), 5829-5840, 2013 | 18 | 2013 |
Identification of a nucleoside analog active against adenosine kinase–expressing plasma cell malignancies U Nayar, J Sadek, J Reichel, D Hernandez-Hopkins, G Akar, PJ Barelli, ... The Journal of clinical investigation 127 (6), 2066-2080, 2017 | 9 | 2017 |
Further studies on vinamidinium salt amine exchange reactions, borohydride reductions, and subsequent transformations JT Gupton, N Telang, X Jia, BC Giglio, JE Eaton, PJ Barelli, M Hovaizi, ... Tetrahedron 66 (44), 8485-8493, 2010 | 5 | 2010 |
Guiding the Arrow: A Dual Targeted Approach to Prostate Cancer Therapy JM Kelly, A Amor-Coarasa, T Wuestemann, A Nikolopoulou, P Barelli, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 43, S14-S15, 2016 | | 2016 |
Exquisite Sensitivity of Plasma Cell Malignancies to a Novel Nucleoside Analog Is Mediated By Overexpressed Adenosine Kinase U Nayar, J Sadek, JB Reichel, D Bunn, D Hernandez-Hopkins, P Barelli, ... Blood, The Journal of the American Society of Hematology 126 (23), 1812-1812, 2015 | | 2015 |
Genomics-based resistome analysis revealed endogenous adenosine kinase levels as a chief determinant of specificity for a novel nucleoside analog lymphoma inhibitor U Nayar, J Reichel, J Sadek, D Hernandez-Hopkins, G Akar, H Zhou, ... Cancer Research 75 (15_Supplement), 4496-4496, 2015 | | 2015 |
New indole building blocks for the regiocontrolled construction of indole appended pyrimidines and pyrazoles SQ Smith, KR Crocker, ST Dudek, CM Lariviere, J Gupton, N Telang, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
MedChemComm c2md20320k C Da, N Telang, K Hall, E Kluball, P Barelli, K Finzel, X Jia, JT Gupton, ... | | |