Analysis of protein-coding genetic variation in 60,706 humans M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ... Nature 536 (7616), 285-291, 2016 | 10598 | 2016 |
Finding the missing heritability of complex diseases TA Manolio, FS Collins, NJ Cox, DB Goldstein, LA Hindorff, DJ Hunter, ... Nature 461 (7265), 747-753, 2009 | 9989 | 2009 |
A map of human genome variation from population-scale sequencing GP Consortium Nature 467 (7319), 1061-1073, 2010 | 8929* | 2010 |
An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium Nature 491 (7422), 56, 2012 | 8539 | 2012 |
Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7661 | 2014 |
Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets EZ Macosko, A Basu, R Satija, J Nemesh, K Shekhar, M Goldman, I Tirosh, ... Cell 161 (5), 1202-1214, 2015 | 7332 | 2015 |
A haplotype map of the human genome IHM Consortium Nature 437 (7063), 1299-320, 2005 | 6353* | 2005 |
Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 6015 | 2013 |
A second generation human haplotype map of over 3.1 million SNPs IHM Consortium Nature 449 (7164), 851-61, 2007 | 5437* | 2007 |
Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4888 | 2015 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3618 | 2010 |
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence G Genovese, AK Kähler, RE Handsaker, J Lindberg, SA Rose, ... New England Journal of Medicine 371 (26), 2477-2487, 2014 | 3553 | 2014 |
A reference panel of 64,976 haplotypes for genotype imputation Nature genetics 48 (10), 1279-1283, 2016 | 3104 | 2016 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2589 | 2010 |
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans CT Murphy, SA McCarroll, CI Bargmann, A Fraser, RS Kamath, J Ahringer, ... Nature 424 (6946), 277-283, 2003 | 2586 | 2003 |
An integrated map of structural variation in 2,504 human genomes PH Sudmant, T Rausch, EJ Gardner, RE Handsaker, A Abyzov, ... Nature 526 (7571), 75-81, 2015 | 2501 | 2015 |
Schizophrenia risk from complex variation of complement component 4 A Sekar, AR Bialas, H De Rivera, A Davis, TR Hammond, N Kamitaki, ... Nature 530 (7589), 177-183, 2016 | 2469 | 2016 |
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2405 | 2013 |
Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007 | 2308 | 2007 |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2204 | 2010 |