| Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function WS Davidson, RAGD Silva, S Chantepie, WR Lagor, MJ Chapman, ... Arteriosclerosis, thrombosis, and vascular biology 29 (6), 870-876, 2009 | 513 | 2009 |
| AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9. LWR Li A, Tanner MR, Lee CM, Hurley AE, De Giorgi M, Jarrett KE, Davis TH ... Mol Ther. 28 (6), 1432-1441, 2020 | 170 | 2020 |
| Trib1 is a lipid- and myocardial infarction–associated gene that regulates hepatic lipogenesis and VLDL production in mice R Burkhardt, SA Toh, WR Lagor, A Birkeland, M Levin, X Li, M Robblee, ... The Journal of clinical investigation 120 (12), 4410-4414, 2010 | 160 | 2010 |
| A self-deleting AAV-CRISPR system for in vivo genome editing A Li, CM Lee, AE Hurley, KE Jarrett, M De Giorgi, W Lu, KS Balderrama, ... Molecular Therapy-Methods & Clinical Development 12, 111-122, 2019 | 126 | 2019 |
| Impact of combined deficiency of hepatic Lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B–containing lipoproteins RJ Brown, WR Lagor, S Sankaranaravanan, T Yasuda, T Quertermous, ... Circulation research 107 (3), 357-364, 2010 | 100 | 2010 |
| The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021 | 98 | 2021 |
| Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease KE Jarrett, CM Lee, YH Yeh, RH Hsu, R Gupta, M Zhang, PJ Rodriguez, ... Scientific reports 7 (1), 44624, 2017 | 98 | 2017 |
| Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial … SH Kassim, H Li, P Bell, S Somanathan, W Lagor, F Jacobs, J Billheimer, ... Human gene therapy 24 (1), 19-26, 2013 | 89 | 2013 |
| Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research KE Jarrett, C Lee, M De Giorgi, A Hurley, BK Gillard, AM Doerfler, A Li, ... Arteriosclerosis, thrombosis, and vascular biology 38 (9), 1997-2006, 2018 | 76 | 2018 |
| In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia X Pan, L Philippen, SK Lahiri, C Lee, SH Park, TA Word, N Li, KE Jarrett, ... Circulation research 123 (8), 953-963, 2018 | 75 | 2018 |
| TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis C Wang, Y He, P Xu, Y Yang, K Saito, Y Xia, X Yan, A Hinton Jr, C Yan, ... Nature communications 9 (1), 1544, 2018 | 71 | 2018 |
| A chemical chaperone improves muscle function in mice with a RyR1 mutation CS Lee, AD Hanna, H Wang, A Dagnino-Acosta, AD Joshi, M Knoblauch, ... Nature communications 8 (1), 14659, 2017 | 67 | 2017 |
| Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo WR Lagor, RJ Brown, SA Toh, JS Millar, IV Fuki, M de la Llera-Moya, ... Arteriosclerosis, thrombosis, and vascular biology 29 (1), 40-46, 2009 | 64 | 2009 |
| Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model B Bissig-Choisat, L Wang, X Legras, PK Saha, L Chen, P Bell, ... Nature communications 6 (1), 7339, 2015 | 63 | 2015 |
| Atrial-specific gene delivery using an adeno-associated viral vector L Ni, L Scott Jr, HM Campbell, X Pan, KM Alsina, J Reynolds, ... Circulation research 124 (2), 256-262, 2019 | 56 | 2019 |
| Targeting adipose tissue via systemic gene therapy SM O'Neill, C Hinkle, SJ Chen, A Sandhu, R Hovhannisyan, S Stephan, ... Gene therapy 21 (7), 653-661, 2014 | 47 | 2014 |
| Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter LR Boone, WR Lagor, M de la Llera Moya, MI Niesen, GH Rothblat, ... Atherosclerosis 218 (1), 77-82, 2011 | 46 | 2011 |
| Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein AI transgenic mice N Nijstad, JF de Boer, WR Lagor, M Toelle, D Usher, W Annema, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2011 | 45 | 2011 |
| Overview of the LDL receptor: relevance to cholesterol metabolism and future approaches for the treatment of coronary heart disease WR Lagor, JS Millar Journal of Receptor, Ligand and Channel Research 3, 1-14, 2009 | 44 | 2009 |
| CRISPR/Cas9: at the cutting edge of hepatology FP Pankowicz, KE Jarrett, WR Lagor, KD Bissig Gut 66 (7), 1329-1340, 2017 | 41 | 2017 |
