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Gerben Bouma
Gerben Bouma
Verified email at gsk.com
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Cited by
Year
Stable gene transfer to muscle using non-integrating lentiviral vectors
L Apolonia, SN Waddington, C Fernandes, NJ Ward, G Bouma, ...
Molecular Therapy 15 (11), 1947-1954, 2007
2332007
The Wiskott-Aldrich syndrome: the actin cytoskeleton and immune cell function
MP Blundell, A Worth, G Bouma, AJ Thrasher
Disease markers 29 (3-4), 157-175, 2010
1432010
Increased serum levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin
G Bouma, WK Lam-Tse, AF Wierenga-Wolf, HA Drexhage, MA Versnel
Diabetes 53 (8), 1979-1986, 2004
1402004
Wiskott–Aldrich syndrome: immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation
G Bouma, SO Burns, AJ Thrasher
Immunobiology 214 (9-10), 778-790, 2009
1382009
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice
M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ...
Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012
1242012
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis
A Meyer-Bahlburg, S Becker-Herman, S Humblet-Baron, S Khim, ...
Blood, The Journal of the American Society of Hematology 112 (10), 4158-4169, 2008
1112008
Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells
G Bouma, S Burns, AJ Thrasher
Blood, The Journal of the American Society of Hematology 110 (13), 4278-4284, 2007
1102007
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy
K Karwacz, S Mukherjee, L Apolonia, MP Blundell, G Bouma, D Escors, ...
Journal of Virology 83 (7), 3094-3103, 2009
1012009
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming
G Bouma, A Mendoza-Naranjo, MP Blundell, E De Falco, KL Parsley, ...
Blood, The Journal of the American Society of Hematology 118 (9), 2492-2501, 2011
972011
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation
A Mendoza-Naranjo, G Bouma, C Pereda, M Ramírez, KF Webb, ...
The Journal of Immunology 187 (6), 3121-3132, 2011
942011
Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1
J Record, D Malinova, HL Zenner, V Plagnol, K Nowak, F Syed, G Bouma, ...
Blood, The Journal of the American Society of Hematology 126 (13), 1527-1535, 2015
832015
Recent advances in the understanding of genetic defects of neutrophil number and function
G Bouma, PJ Ancliff, AJ Thrasher, SO Burns
British journal of haematology 151 (4), 312-326, 2010
812010
Phosphorylation of WASp is a key regulator of activity and stability in vivo
MP Blundell, G Bouma, J Metelo, A Worth, Y Calle, LA Cowell, ...
Proceedings of the National Academy of Sciences 106 (37), 15738-15743, 2009
722009
WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts
D Malinova, M Fritzsche, CR Nowosad, H Armer, PMG Munro, ...
Journal of Leucocyte Biology 99 (5), 699-710, 2016
672016
A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells
A Olivier, L Jeanson-Leh, G Bouma, D Compagno, J Blondeau, K Seye, ...
Molecular Therapy 13 (4), 729-737, 2006
652006
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells
PP Lee, D Lobato-Márquez, N Pramanik, A Sirianni, V Daza-Cajigal, ...
Nature communications 8 (1), 1576, 2017
612017
NOD mice have a severly impaired ability to recruit leukocytes into sites of inflammation
G Bouma, T Nikolic, JMC Coppens, CG van Helden‐Meeuwsen, ...
European journal of immunology 35 (1), 225-235, 2005
592005
Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre‐diabetic islets in NOD mice
G Bouma, JMC Coppens, S Mourits, T Nikolic, S Sozzani, HA Drexhage, ...
European journal of immunology 35 (8), 2386-2396, 2005
572005
Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro
T Nikolic, G Bouma, HA Drexhage, PJM Leenen
Journal of leukocyte biology 78 (1), 70-79, 2005
532005
An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytes
G Bouma, JMC Coppens, WK Lam-Tse, W Luini, K Sintnicolaas, ...
Clinical & Experimental Immunology 141 (3), 509-517, 2005
482005
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