Dr. Siyuan Zhang
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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ...
Nature 527 (7576), 100-104, 2015
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
S Zhang, WC Huang, P Li, H Guo, SB Poh, SW Brady, Y Xiong, LM Tseng, ...
Nature medicine 17 (4), 461-469, 2011
Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells
S Zhang, CN Ong, HM Shen
Cancer letters 208 (2), 143-153, 2004
Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms
S Zhang, YK Won, CN Ong, HM Shen
Current Medicinal Chemistry-Anti-Cancer Agents 5 (3), 239-249, 2005
PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer
FJ Esteva, H Guo, S Zhang, C Santa-Maria, S Stone, JS Lanchbury, ...
The American journal of pathology 177 (4), 1647-1656, 2010
PI (3) king apart PTEN's role in cancer
S Zhang, D Yu
Clinical Cancer Research 16 (17), 4325-4330, 2010
Suggestive annotation: A deep active learning framework for biomedical image segmentation
L Yang, Y Zhang, J Chen, S Zhang, DZ Chen
International conference on medical image computing and computer-assisted …, 2017
Targeting Src family kinases in anti-cancer therapies: turning promise into triumph
S Zhang, D Yu
Trends in pharmacological sciences 33 (3), 122-128, 2012
Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
PK Morrow, GM Wulf, J Ensor, DJ Booser, JA Moore, PR Flores, Y Xiong, ...
Journal of Clinical Oncology 29 (23), 3126, 2011
Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells
J Zhou, S Zhang, O Choon-Nam, HM Shen
Biochemical pharmacology 72 (2), 132-144, 2006
Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells
S Zhang, ZN Lin, CF Yang, X Shi, CN Ong, HM Shen
Carcinogenesis 25 (11), 2191-2199, 2004
c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly (ADP-ribose) polymerase-1 activation
S Zhang, Y Lin, YS Kim, MP Hande, ZG Liu, HM Shen
Cell Death & Differentiation 14 (5), 1001-1010, 2007
Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis
S Zhang, CN Ong, HM Shen
Cancer letters 211 (2), 175-188, 2004
SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases
S Zhang, WC Huang, L Zhang, C Zhang, FJ Lowery, Z Ding, H Guo, ...
Cancer research 73 (18), 5764-5774, 2013
Evolving concepts of tumor heterogeneity
VR Zellmer, S Zhang
Cell & bioscience 4 (1), 1-8, 2014
A poisson-gaussian denoising dataset with real fluorescence microscopy images
Y Zhang, Y Zhu, E Nichols, Q Wang, S Zhang, C Smith, S Howard
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern …, 2019
Microfluidic device design, fabrication, and testing protocols
M Lake, C Narciso, K Cowdrick, T Storey, S Zhang, J Zartman, D Hoelzle
Protoc. Exch 10 (10.1038), 2015
3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth
J Casey, X Yue, TD Nguyen, A Acun, VR Zellmer, S Zhang, P Zorlutuna
Biomedical materials 12 (2), 025009, 2017
Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions
X Yue, TD Nguyen, V Zellmer, S Zhang, P Zorlutuna
Biomaterials 170, 37-48, 2018
Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells
JA Mason, CA Davison-Versagli, AK Leliaert, DJ Pape, C McCallister, ...
Cell Death & Differentiation 23 (8), 1271-1282, 2016
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