Balram Chowbay
Balram Chowbay
Professor of Clinical Pharmacology, National Cancer Centre Singapore and Duke-NUS Singapore
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Polymorphism of human cytochrome P450 enzymes and its clinical impact
SF Zhou, JP Liu, B Chowbay
Drug metabolism reviews 41 (2), 89-295, 2009
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
Herbal modulation of P‐glycoprotein
S Zhou, LY Lim, B Chowbay
Drug metabolism reviews 36 (1), 57-104, 2004
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
B Chowbay, S Cumaraswamy, YB Cheung, Q Zhou, EJD Lee
Pharmacogenetics and Genomics 13 (2), 89-95, 2003
Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer
P Saladores, T Mürdter, D Eccles, B Chowbay, NK Zgheib, S Winter, ...
The pharmacogenomics journal 15 (1), 84-94, 2015
Phase I pharmacokinetic study of a weekly liposomal paclitaxel formulation (Genexol®-PM) in patients with solid tumors
WT Lim, EH Tan, CK Toh, SW Hee, SS Leong, PCS Ang, NS Wong, ...
Annals of oncology 21 (2), 382-388, 2010
Meta‐analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression
B Chowbay, H Li, M David, Y Bun Cheung, EJD Lee
British journal of clinical pharmacology 60 (2), 159-171, 2005
Pharmacogenetics of target genes across doxorubicin disposition pathway: a review
S Lal, A Mahajan, W Ning Chen, B Chowbay
Current drug metabolism 11 (1), 115-128, 2010
Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan‐induced neutropenia in Asian cancer patients
SR Jada, R Lim, CI Wong, X Shu, SC Lee, Q Zhou, BC Goh, B Chowbay
Cancer science 98 (9), 1461-1467, 2007
An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore
B Chowbay, S Zhou, EJD Lee
Drug metabolism reviews 37 (2), 327-378, 2005
Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients
JSL Lim, XA Chen, O Singh, YS Yap, RCH Ng, NS Wong, M Wong, ...
British journal of clinical pharmacology 71 (5), 737-750, 2011
Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma
DSW Tan, FT Chong, HS Leong, SY Toh, DP Lau, XL Kwang, X Zhang, ...
Nature medicine 23 (10), 1167-1175, 2017
Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients
S Lal, ZW Wong, E Sandanaraj, X Xiang, PCS Ang, EJD Lee, B Chowbay
Cancer science 99 (4), 816-823, 2008
Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer
Q Zhou, A Sparreboom, EH Tan, YB Cheung, A Lee, D Poon, EJD Lee, ...
British journal of clinical pharmacology 59 (4), 415-424, 2005
Pharmacogenetics of SLCO1B1 gene and the impact of* 1b and* 15 haplotypes on irinotecan disposition in Asian cancer patients
X Xiang, SR Jada, HH Li, L Fan, L San Tham, CI Wong, SC Lee, R Lim, ...
Pharmacogenetics and genomics 16 (9), 683-691, 2006
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci
T Aung, M Ozaki, MC Lee, U Schlötzer-Schrehardt, G Thorleifsson, ...
Nature genetics 49 (7), 993-1004, 2017
A Phase II Study of Pazopanib in Asian Patients with Recurrent/Metastatic Nasopharyngeal CarcinomaPazopanib in Advanced Nasopharyngeal Carcinoma
WT Lim, QS Ng, P Ivy, SS Leong, O Singh, B Chowbay, F Gao, CH Thng, ...
Clinical cancer research 17 (16), 5481-5489, 2011
Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain …
XY Yu, SG Lin, X Chen, ZW Zhou, J Liang, W Duan, B Chowbay, JY Wen, ...
Current drug metabolism 8 (4), 365-377, 2007
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge
XY Yu, SG Lin, ZW Zhou, X Chen, J Liang, PQ Liu, W Duan, B Chowbay, ...
Current drug metabolism 8 (4), 325-340, 2007
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome
T Aung, M Ozaki, T Mizoguchi, RR Allingham, Z Li, A Haripriya, S Nakano, ...
Nature genetics 47 (4), 387-392, 2015
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