| A systematic survey identifies prions and illuminates sequence features of prionogenic proteins S Alberti, R Halfmann, O King, A Kapila, S Lindquist Cell 137 (1), 146-158, 2009 | 1097 | 2009 |
| Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation X Cai, J Chen, H Xu, S Liu, QX Jiang, R Halfmann, ZJ Chen Cell 156 (6), 1207-1222, 2014 | 597 | 2014 |
| Prions are a common mechanism for phenotypic inheritance in wild yeasts R Halfmann, DF Jarosz, SK Jones, A Chang, AK Lancaster, S Lindquist Nature 482 (7385), 363-368, 2012 | 463 | 2012 |
| Epigenetics in the extreme: prions and the inheritance of environmentally acquired traits R Halfmann, S Lindquist Science 330 (6004), 629-632, 2010 | 276 | 2010 |
| Screening for amyloid aggregation by semi-denaturing detergent-agarose gel electrophoresis R Halfmann, S Lindquist Journal of visualized experiments: JoVE, 2008 | 225 | 2008 |
| Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins R Halfmann, S Alberti, R Krishnan, N Lyle, CW O'Donnell, OD King, ... Molecular cell 43 (1), 72-84, 2011 | 203 | 2011 |
| Chaperone-dependent amyloid assembly protects cells from prion toxicity PM Douglas, S Treusch, HY Ren, R Halfmann, ML Duennwald, ... Proceedings of the National Academy of Sciences 105 (20), 7206-7211, 2008 | 197 | 2008 |
| Prions, protein homeostasis, and phenotypic diversity R Halfmann, S Alberti, S Lindquist Trends in cell biology 20 (3), 125-133, 2010 | 195 | 2010 |
| Heritable remodeling of yeast multicellularity by an environmentally responsive prion DL Holmes, AK Lancaster, S Lindquist, R Halfmann Cell 153 (1), 153-165, 2013 | 193 | 2013 |
| Small-molecule activation of the TRAIL receptor DR5 in human cancer cells G Wang, X Wang, H Yu, S Wei, N Williams, DL Holmes, R Halfmann, ... Nature chemical biology 9 (2), 84-89, 2013 | 120 | 2013 |
| Prion formation by a yeast GLFG nucleoporin R Halfmann, JR Wright, S Alberti, S Lindquist, M Rexach Prion 6 (4), 391-399, 2012 | 103 | 2012 |
| Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeast S Alberti, R Halfmann, S Lindquist Methods in enzymology 470, 709-734, 2010 | 86 | 2010 |
| Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior T Khan, TS Kandola, J Wu, S Venkatesan, E Ketter, JJ Lange, AR Gama, ... Molecular cell 71 (1), 155-168. e7, 2018 | 81 | 2018 |
| A method for probing the mutational landscape of amyloid structure CW O'Donnell, J Waldispühl, M Lis, R Halfmann, S Devadas, S Lindquist, ... Bioinformatics 27 (13), i34-i42, 2011 | 77 | 2011 |
| A self-perpetuating repressive state of a viral replication protein blocks superinfection by the same virus XF Zhang, R Sun, Q Guo, S Zhang, T Meulia, R Halfmann, D Li, F Qu PLoS Pathogens 13 (3), e1006253, 2017 | 50 | 2017 |
| Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation MJ Holliday, A Witt, A Rodríguez Gama, BT Walters, CP Arthur, ... Nature Communications 10 (1), 3070, 2019 | 40 | 2019 |
| A glass menagerie of low complexity sequences. R Halfmann Current Opinion in Structural Biology 38, 9-16, 2016 | 38 | 2016 |
| The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death NL Nuckolls, AC Mok, JJ Lange, K Yi, TS Kandola, AM Hunn, ... Elife 9, e55694, 2020 | 28 | 2020 |
| DNCON2_Inter: predicting interchain contacts for homodimeric and homomultimeric protein complexes using multiple sequence alignments of monomers and deep learning F Quadir, RS Roy, R Halfmann, J Cheng Scientific reports 11 (1), 12295, 2021 | 24 | 2021 |
| Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structureguided surface engineering DW Close, CD Paul, PS Langan, MCJ Wilce, DAK Traore, R Halfmann, ... Proteins: Structure, Function, and Bioinformatics 83 (7), 1225-1237, 2015 | 23 | 2015 |
Alex K. LancasterPartner, Amber Biology; Researcher, IGDORE; Research Scholar, Ronin Institute在 igdore.org 的电子邮件经过验证
