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Gary Coombs
Gary Coombs
Professor of Biology, Waldorf University
Verified email at waldorf.edu - Homepage
Title
Cited by
Cited by
Year
WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
GS Coombs, J Yu, CA Canning, CA Veltri, TM Covey, JK Cheong, ...
Journal of cell science 123 (19), 3357-3367, 2010
2102010
Protein phosphatase 1 regulates assembly and function of the β‐catenin degradation complex
W Luo, A Peterson, BA Garcia, G Coombs, B Kofahl, R Heinrich, ...
The EMBO journal 26 (6), 1511-1521, 2007
1702007
Substrate specificity of prostate-specific antigen (PSA)
GS Coombs, RC Bergstrom, JL Pellequer, SI Baker, M Navre, MM Smith, ...
Chemistry & biology 5 (9), 475-488, 1998
1541998
Optimal subsite occupancy and design of a selective inhibitor of urokinase
SH Ke, GS Coombs, K Tachias, DR Corey, EL Madison
Journal of Biological Chemistry 272 (33), 20456-20462, 1997
1511997
Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase
R Friedrich, P Fuentes-Prior, E Ong, G Coombs, M Hunter, R Oehler, ...
Journal of Biological Chemistry 277 (3), 2160-2168, 2002
1462002
Origins of the specificity of tissue-type plasminogen activator.
L Ding, GS Coombs, L Strandberg, M Navre, DR Corey, EL Madison
Proceedings of the National Academy of Sciences 92 (17), 7627-7631, 1995
1041995
Substrate Specificity of Tissue Type Plasminogen Activator: CHARACTERIZATION OF THE FIBRIN INDEPENDENT SPECIFICITY OF t-PA FOR PLASMINOGEN (∗)
EL Madison, GS Coombs, DR Corey
Journal of Biological Chemistry 270 (13), 7558-7562, 1995
1001995
Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer
TM Covey, K Edes, GS Coombs, DM Virshup, FA Fitzpatrick
PLoS One 5 (10), e13545, 2010
912010
Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates
LS Hervio, GS Coombs, RC Bergstrom, K Trivedi, DR Corey, EL Madison
Chemistry & biology 7 (6), 443-452, 2000
882000
Distinguishing the specificities of closely related proteases: role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase
SH Ke, GS Coombs, K Tachias, M Navre, DR Corey, EL Madison
Journal of Biological Chemistry 272 (26), 16603-16609, 1997
841997
Wnt signaling in development, disease and translational medicine
GS Coombs, TM Covey, DM Virshup
Current drug targets 9 (7), 513-531, 2008
832008
Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer
GS Coombs, AA Schmitt, CA Canning, A Alok, ICC Low, N Banerjee, ...
Oncogene 31 (2), 213-225, 2012
782012
Negative Regulation of LRP6 Function by Casein Kinase I ϵ Phosphorylation
W Swiatek, H Kang, BA Garcia, J Shabanowitz, GS Coombs, DF Hunt, ...
Journal of biological chemistry 281 (18), 12233-12241, 2006
682006
ToIC and DsbA are needed for the secretion of STB, a heat‐stable enterotoxin of Escherichia coli
DT Foreman, Y Martinez, G Coombs, A Torres, YM Kupersztoch
Molecular microbiology 18 (2), 237-245, 1995
671995
Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains
GS Coombs, MS Rao, AJ Olson, PE Dawson, EL Madison
Journal of biological chemistry 274 (34), 24074-24079, 1999
561999
Distinct Mechanisms Contribute to Stringent Substrate Specificity of Tissue-type Plasminogen Activator (∗)
GS Coombs, AT Dang, EL Madison, DR Corey
Journal of Biological Chemistry 271 (8), 4461-4467, 1996
511996
Trypsin specificity increased through substrate-assisted catalysis
DR Corey, WS Willett, GS Coombs, CS Craik
Biochemistry 34 (36), 11521-11527, 1995
491995
Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors
E Zeslawska, U Jacob, A Schweinitz, G Coombs, W Bode, E Madison
Journal of molecular biology 328 (1), 109-118, 2003
482003
Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives
MWB McCulloch, GS Coombs, N Banerjee, TS Bugni, KM Cannon, ...
Bioorganic & medicinal chemistry 17 (6), 2189-2198, 2009
472009
Directing sequence-specific proteolysis to new targets: the influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and …
GS Coombs, RC Bergstrom, EL Madison, DR Corey
Journal of Biological Chemistry 273 (8), 4323-4328, 1998
411998
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