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Timothy Sampson
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Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease
TR Sampson, JW Debelius, T Thron, S Janssen, GG Shastri, ZE Ilhan, ...
Cell 167 (6), 1469-1480. e12, 2016
30302016
The central nervous system and the gut microbiome
G Sharon, TR Sampson, DH Geschwind, SK Mazmanian
Cell 167 (4), 915-932, 2016
12252016
Control of brain development, function, and behavior by the microbiome
TR Sampson, SK Mazmanian
Cell host & microbe 17 (5), 565-576, 2015
11242015
A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
TR Sampson, SD Saroj, AC Llewellyn, YL Tzeng, DS Weiss
Nature 497 (7448), 254-257, 2013
5292013
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice
TR Sampson, C Challis, N Jain, A Moiseyenko, MS Ladinsky, GG Shastri, ...
elife 9, e53111, 2020
3132020
Cas9-mediated targeting of viral RNA in eukaryotic cells
AA Price, TR Sampson, HK Ratner, A Grakoui, DS Weiss
Proceedings of the National Academy of Sciences 112 (19), 6164-6169, 2015
2892015
Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice
C Challis, A Hori, TR Sampson, BB Yoo, RC Challis, AM Hamilton, ...
Nature Neuroscience 23 (3), 327-336, 2020
2862020
Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway
TR Sampson, X Liu, MR Schroeder, CS Kraft, EM Burd, DS Weiss
Antimicrobial agents and chemotherapy 56 (11), 5642-5649, 2012
2222012
Subversion of host recognition and defense systems by Francisella spp
CL Jones, BA Napier, TR Sampson, AC Llewellyn, MR Schroeder, ...
Microbiology and Molecular Biology Reviews 76 (2), 383-404, 2012
1652012
Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation
C Chen, J Liao, Y Xia, X Liu, R Jones, J Haran, B McCormick, ...
Gut 71 (11), 2233-2252, 2022
1352022
A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion
TR Sampson, BA Napier, MR Schroeder, R Louwen, J Zhao, CY Chin, ...
Proceedings of the National Academy of Sciences 111 (30), 11163-11168, 2014
1052014
Exploiting CRISPR/C as systems for biotechnology
TR Sampson, DS Weiss
Bioessays 36 (1), 34-38, 2014
952014
CRISPR-Cas systems: new players in gene regulation and bacterial physiology
TR Sampson, DS Weiss
Frontiers in cellular and infection microbiology 4, 37, 2014
932014
Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms
ZD Wallen, A Demirkan, G Twa, G Cohen, MN Dean, DG Standaert, ...
Nature communications 13 (1), 6958, 2022
922022
Cas9-nucleic acid complexes and uses related thereto
DS Weiss, A Grakoui, TR Sampson, AA Price
US Patent 10,544,405, 2020
892020
Mycobacteriophages BPs, Angel and Halo: comparative genomics reveals a novel class of ultra-small mobile genetic elements
T Sampson, GW Broussard, LJ Marinelli, D Jacobs-Sera, M Ray, CC Ko, ...
Microbiology 155 (9), 2962-2977, 2009
772009
I can see CRISPR now, even when phage are gone: a view on alternative CRISPR-Cas functions from the prokaryotic envelope
HK Ratner, TR Sampson, DS Weiss
Current opinion in infectious diseases 28 (3), 267-274, 2015
552015
Alternative roles for CRISPR/Cas systems in bacterial pathogenesis
TR Sampson, DS Weiss
PLoS pathogens 9 (10), e1003621, 2013
552013
Repression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognition
CL Jones, TR Sampson, HI Nakaya, B Pulendran, DS Weiss
Cellular microbiology 14 (10), 1531-1543, 2012
482012
The impact of indigenous microbes on Parkinson's disease
T Sampson
Neurobiology of disease 135, 104426, 2020
382020
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Articles 1–20