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Nada Lallous
Nada Lallous
Assistant Professor, University of British Columbia
Verified email at prostatecentre.com
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Cited by
Cited by
Year
Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients
N Lallous, SV Volik, S Awrey, E Leblanc, R Tse, J Murillo, K Singh, ...
Genome Biology 17 (10), 2016
2152016
Moving towards precision urologic oncology: targeting enzalutamide-resistant prostate cancer and mutated forms of the androgen receptor using the novel inhibitor darolutamide …
H Borgmann, N Lallous, D Ozistanbullu, E Beraldi, N Paul, K Dalal, L Fazli, ...
European urology 73 (1), 4-8, 2018
832018
Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
N Lallous, K Dalal, A Cherkasov, PS Rennie
International journal of molecular sciences 14 (6), 12496-12519, 2013
832013
Identification of a potent antiandrogen that targets the BF3 site of the androgen receptor and inhibits enzalutamide-resistant prostate cancer
RSN Munuganti, MDH Hassona, E Leblanc, K Frewin, K Singh, D Ma, ...
Chemistry & biology 21 (11), 1476-1485, 2014
812014
Structure, functional characterization, and evolution of the dihydroorotase domain of human CAD
A Grande-García, N Lallous, C Díaz-Tejada, S Ramón-Maiques
Structure 22 (2), 185-198, 2014
742014
Androgen receptor-binding sites are highly mutated in prostate cancer
T Morova, DR McNeill, N Lallous, M Gönen, K Dalal, DM Wilson III, ...
Nature communications 11 (1), 832, 2020
532020
Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models
L Nappi, AH Aguda, N Al Nakouzi, B Lelj-Garolla, E Beraldi, N Lallous, ...
The Journal of clinical investigation 130 (2), 699-714, 2020
522020
The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers
N Lallous, P Legrand, AG McEwen, S Ramón-Maiques, JP Samama, ...
PloS one 6 (11), e27599, 2011
522011
Androgen receptor plasticity and its implications for prostate cancer therapy
O Snow, N Lallous, K Singh, N Lack, P Rennie, A Cherkasov
Cancer treatment reviews 81, 101871, 2019
492019
An oncofetal glycosaminoglycan modification provides therapeutic access to cisplatin-resistant bladder cancer
R Seiler, HZ Oo, D Tortora, TM Clausen, CK Wang, G Kumar, MA Pereira, ...
European urology 72 (1), 142-150, 2017
482017
Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer
LA Carabet, N Lallous, E Leblanc, F Ban, H Morin, S Lawn, F Ghaidi, ...
European journal of medicinal chemistry 160, 108-119, 2018
472018
Bypassing drug resistance mechanisms of prostate cancer with small molecules that target androgen Receptor–Chromatin interactions
K Dalal, M Che, NS Que, A Sharma, R Yang, N Lallous, H Borgmann, ...
Molecular cancer therapeutics 16 (10), 2281-2291, 2017
362017
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression
F Zhang, M Biswas, S Massah, J Lee, S Lingadahalli, S Wong, C Wells, ...
Nucleic Acids Research 51 (1), 99-116, 2023
352023
Discovery of new catalytic topoisomerase II inhibitors for anticancer therapeutics
VM Matias-Barrios, M Radaeva, Y Song, Z Alperstein, AR Lee, V Schmitt, ...
Frontiers in oncology 10, 633142, 2021
352021
Computer-aided discovery of small molecules targeting the RNA splicing activity of hnRNP A1 in castration-resistant prostate cancer
LA Carabet, E Leblanc, N Lallous, H Morin, F Ghaidi, J Lee, PS Rennie, ...
Molecules 24 (4), 763, 2019
302019
Targeting binding function-3 of the androgen receptor blocks its co-chaperone interactions, nuclear translocation, and activation
N Lallous, E Leblanc, RSN Munuganti, MDH Hassona, NA Nakouzi, ...
Molecular cancer therapeutics 15 (12), 2936-2945, 2016
302016
In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α
K Singh, RSN Munuganti, E Leblanc, YL Lin, E Leung, N Lallous, M Butler, ...
Breast Cancer Research 17, 1-17, 2015
302015
Cheminformatics Modeling of Adverse Drug Responses by Clinically Relevant Mutants of Human Androgen Receptor
AC Naman Paul, Lavinia Arielle Carabet, Nada Lallous, Takeshi Yamazaki ...
Journal of Chemical Information and Modeling, 2016
202016
Development of an androgen receptor inhibitor targeting the N-Terminal domain of androgen receptor for treatment of castration resistant prostate cancer
F Ban, E Leblanc, AD Cavga, CCF Huang, MR Flory, F Zhang, ...
Cancers 13 (14), 3488, 2021
192021
Development of novel inhibitors targeting the d-box of the dna binding domain of androgen receptor
M Radaeva, F Ban, F Zhang, E LeBlanc, N Lallous, PS Rennie, ...
International journal of molecular sciences 22 (5), 2493, 2021
172021
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