| Accelerating discovery of functional mutant alleles in cancer MT Chang, TS Bhattarai, AM Schram, CM Bielski, MTA Donoghue, ... Cancer discovery 8 (2), 174-183, 2018 | 312 | 2018 |
| Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ... Science 366 (6466), 714-723, 2019 | 225 | 2019 |
| Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer LM Smyth, SA Piha-Paul, HH Won, AM Schram, C Saura, S Loi, J Lu, ... Cancer discovery 10 (2), 198-213, 2020 | 108 | 2020 |
| Widespread selection for oncogenic mutant allele imbalance in cancer CM Bielski, MTA Donoghue, M Gadiya, AJ Hanrahan, HH Won, ... Cancer cell 34 (5), 852-862. e4, 2018 | 91 | 2018 |
| Altered nuclear export signal recognition as a driver of oncogenesis J Taylor, M Sendino, AN Gorelick, A Pastore, MT Chang, AV Penson, ... Cancer discovery 9 (10), 1452-1467, 2019 | 71 | 2019 |
| Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA AN Gorelick, M Kim, WK Chatila, K La, AA Hakimi, MF Berger, BS Taylor, ... Nature metabolism 3 (4), 558-570, 2021 | 60 | 2021 |
| Patterns of ectopy leading to increased risk of fatal or near-fatal cardiac arrhythmia in patients with depressed left ventricular function after an acute myocardial infarction C Lerma, A Gorelick, RN Ghanem, L Glass, HV Huikuri Europace 15 (9), 1304-1312, 2013 | 41 | 2013 |
| TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors E Cocco, JE Lee, S Kannan, AM Schram, HH Won, S Shifman, A Kulick, ... Cancer discovery 11 (1), 126-141, 2021 | 39 | 2021 |
| Phase and context shape the function of composite oncogenic mutations AN Gorelick, FJ Sánchez-Rivera, Y Cai, CM Bielski, E Biederstedt, ... Nature 582 (7810), 100-103, 2020 | 39 | 2020 |
| V211D mutation in MEK1 causes resistance to MEK inhibitors in colon cancer Y Gao, A Maria, N Na, A da Cruz Paula, AN Gorelick, JF Hechtman, ... Cancer discovery 9 (9), 1182-1191, 2019 | 34 | 2019 |
| Putative drivers of aggressiveness in TCEB1-mutant renal cell carcinoma: an emerging entity with variable clinical course RG DiNatale, AN Gorelick, V Makarov, KA Blum, AW Silagy, B Freeman, ... European urology focus 7 (2), 381-389, 2021 | 33 | 2021 |
| Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer AJ Hanrahan, BE Sylvester, MT Chang, A Elzein, J Gao, W Han, Y Liu, ... Cancer research 80 (19), 4233-4243, 2020 | 30 | 2020 |
| Mitonuclear genotype remodels the metabolic and microenvironmental landscape of Hürthle cell carcinoma I Ganly, EM Liu, F Kuo, V Makarov, Y Dong, J Park, Y Gong, AN Gorelick, ... Science advances 8 (25), eabn9699, 2022 | 13 | 2022 |
| AKT mutant allele-specific activation dictates pharmacologic sensitivities T Shrestha Bhattarai, T Shamu, AN Gorelick, MT Chang, D Chakravarty, ... Nature Communications 13 (1), 2111, 2022 | 12 | 2022 |
| Altered nuclear export signal recognition as a driver of oncogenesis. Cancer Discov. 2019; 9: 1452–1467. doi: 10.1158/2159-8290 J Taylor, M Sendino, AN Gorelick, A Pastore, MT Chang, AV Penson, ... CD-19-0298.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 11 | |
| Mutational clocks tick differently across species AN Gorelick, K Naxerova Nature 604 (7906), 435-436, 2022 | 4 | 2022 |
| Respiratory complex and tissue lineage drive mutational patterns in the tumor mitochondrial genome AN Gorelick, M Kim, WK Chatila, K La, AA Hakimi, BS Taylor, ... BioRxiv, 2020.08. 18.256362, 2020 | 3 | 2020 |
| Lymphatic invasion of Plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer E Küçükköse, J Laoukili, AN Gorelick, S Degner, MM Laclé, ... Gastroenterology 165 (2), 429-444. e15, 2023 | 2 | 2023 |
| Abstract NG16: Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ... Cancer Research 80 (16_Supplement), NG16-NG16, 2020 | 1 | 2020 |
| Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes M Kim, AN Gorelick, I Vàzquez-García, MJ Williams, S Salehi, H Shi, ... Nature Genetics, 1-11, 2024 | | 2024 |
Ed ReznikMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
