Takafumi Suzuki
Takafumi Suzuki
Tohoku University Graduate School of Medicine
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Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
EH Kobayashi, T Suzuki, R Funayama, T Nagashima, M Hayashi, ...
Nature communications 7 (1), 11624, 2016
Molecular basis of the Keap1–Nrf2 system
T Suzuki, M Yamamoto
Free Radical Biology and Medicine 88, 93-100, 2015
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth
T Ohta, K Iijima, M Miyamoto, I Nakahara, H Tanaka, M Ohtsuji, T Suzuki, ...
Cancer research 68 (5), 1303-1309, 2008
Toward clinical application of the Keap1–Nrf2 pathway
T Suzuki, H Motohashi, M Yamamoto
Trends in pharmacological sciences 34 (6), 340-346, 2013
Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity
T Yamamoto, T Suzuki, A Kobayashi, J Wakabayashi, J Maher, ...
Molecular and cellular biology 28 (8), 2758-2770, 2008
Identification of the interactive interface and phylogenic conservation of the Nrf2‐Keap1 system
M Kobayashi, K Itoh, T Suzuki, H Osanai, K Nishikawa, Y Katoh, Y Takagi, ...
Genes to Cells 7 (8), 807-820, 2002
Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress
T Suzuki, M Yamamoto
Journal of Biological Chemistry 292 (41), 16817-16824, 2017
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
T Saito, Y Ichimura, K Taguchi, T Suzuki, T Mizushima, K Takagi, Y Hirose, ...
Nature communications 7 (1), 12030, 2016
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
K Takaya, T Suzuki, H Motohashi, K Onodera, S Satomi, TW Kensler, ...
Free Radical Biology and Medicine 53 (4), 817-827, 2012
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
T Hidaka, E Ogawa, EH Kobayashi, T Suzuki, R Funayama, T Nagashima, ...
Nature immunology 18 (1), 64-73, 2017
Characterizations of three major cysteine sensors of Keap1 in stress response
R Saito, T Suzuki, K Hiramoto, S Asami, E Naganuma, H Suda, T Iso, ...
Molecular and cellular biology 36 (2), 271-284, 2016
Genetic analysis of cytoprotective functions supported by graded expression of Keap1
K Taguchi, JM Maher, T Suzuki, Y Kawatani, H Motohashi, M Yamamoto
Molecular and cellular biology 30 (12), 3016-3026, 2010
Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung
H Satoh, T Moriguchi, K Taguchi, J Takai, JM Maher, T Suzuki, ...
Carcinogenesis 31 (10), 1833-1843, 2010
Molecular mechanism of cellular oxidative stress sensing by Keap1
T Suzuki, A Muramatsu, R Saito, T Iso, T Shibata, K Kuwata, S Kawaguchi, ...
Cell reports 28 (3), 746-758. e4, 2019
The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation
M Kobayashi, K Nishikawa, T Suzuki, M Yamamoto
Developmental biology 232 (2), 315-326, 2001
Mitochondrial SKN-1/Nrf mediates a conserved starvation response
J Paek, JY Lo, SD Narasimhan, TN Nguyen, K Glover-Cutter, ...
Cell metabolism 16 (4), 526-537, 2012
Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression
M Nezu, T Souma, L Yu, T Suzuki, D Saigusa, S Ito, N Suzuki, ...
Kidney international 91 (2), 387-401, 2017
Environmental pollutants and the immune response
T Suzuki, T Hidaka, Y Kumagai, M Yamamoto
Nature Immunology 21 (12), 1486-1495, 2020
Global downstream pathway analysis reveals a dependence of oncogenic NF-E2–related factor 2 mutation on the mTOR growth signaling pathway
T Shibata, S Saito, A Kokubu, T Suzuki, M Yamamoto, S Hirohashi
Cancer research 70 (22), 9095-9105, 2010
Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels
T Suzuki, T Shibata, K Takaya, K Shiraishi, T Kohno, H Kunitoh, K Tsuta, ...
Molecular and cellular biology, 2013
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