| In vivo comparison of 2′‐O‐methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping HA Heemskerk, CL de Winter, SJ de Kimpe, P van Kuik‐Romeijn, ... The journal of gene medicine 11 (3), 257-266, 2009 | 277 | 2009 |
| Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms A Aartsma-Rus, L Van Vliet, M Hirschi, AAM Janson, H Heemskerk, ... Molecular Therapy 17 (3), 548-553, 2009 | 235 | 2009 |
| Phage display screening without repetitious selection rounds P AC’t Hoen, SMG Jirka, R Bradley, EA Schultes, B Aguilera, KH Pang, ... Analytical biochemistry 421 (2), 622-631, 2012 | 199 | 2012 |
| Preclinical PK and PD studies on 2′-O-methyl-phosphorothioate RNA antisense oligonucleotides in the mdx mouse model H Heemskerk, C De Winter, P Van Kuik, N Heuvelmans, P Sabatelli, ... Molecular Therapy 18 (6), 1210-1217, 2010 | 165 | 2010 |
| Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice M van Putten, M Hulsker, C Young, VD Nadarajah, H Heemskerk, ... The FASEB Journal 27 (6), 2484-2495, 2013 | 126 | 2013 |
| Peptide Conjugation of 2′-O-methyl Phosphorothioate Antisense Oligonucleotides Enhances Cardiac Uptake and Exon Skipping in mdx Mice SMG Jirka, H Heemskerk, CL Tanganyika-de Winter, D Muilwijk, KH Pang, ... nucleic acid therapeutics 24 (1), 25-36, 2014 | 53 | 2014 |
| Accurate quantification of dystrophin mRNA and exon skipping levels in duchenne muscular dystrophy P Spitali, H Heemskerk, RHAM Vossen, A Ferlini, JT Den Dunnen, ... Laboratory Investigation 90 (9), 1396-1402, 2010 | 49 | 2010 |
| Development of Antisense‐Mediated Exon Skipping as a Treatment for Duchenne Muscular Dystrophy H Heemskerk, CL De Winter, GJB Van Ommen, JCT Van Deutekom, ... Annals of the New York Academy of Sciences 1175 (1), 71-79, 2009 | 46 | 2009 |
| Long-term exon skipping studies with 2′-O-methyl phosphorothioate antisense oligonucleotides in dystrophic mouse models CL Tanganyika-de Winter, H Heemskerk, TG Karnaoukh, M Van Putten, ... Molecular Therapy—Nucleic Acids 1 (9), e44, 2012 | 44 | 2012 |
| ’t Hoen, PA, van Ommen, GJ, and Aartsma-Rus, AM (2013). Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout … M van Putten, M Hulsker, C Young, VD Nadarajah, H Heemskerk, ... FASEB J 27 (6), 2484-2495, 0 | 31 | |
| Near-common-path interferometer for imaging Fourier-transform spectroscopy in wide-field microscopy DN Wadduwage, VR Singh, H Choi, Z Yaqoob, H Heemskerk, ... Optica 4 (5), 546-556, 2017 | 26 | 2017 |
| Superpixel-based segmentation of muscle fibers in multi-channel microscopy BP Nguyen, H Heemskerk, L Tucker-Kellogg, PTC So BMC systems biology 10 (5), 124, 2016 | 25 | 2016 |
| Prednisolone Treatment Does Not Interfere with 2′-O-Methyl Phosphorothioate Antisense-Mediated Exon Skipping in Duchenne Muscular Dystrophy IEC Verhaart, H Heemskerk, TG Karnaoukh, IGM Kolfschoten, A Vroon, ... Human gene therapy 23 (3), 262-273, 2011 | 24 | 2011 |
| Muscle binding peptides found by phage display as delivery agent for antisense oligonucleotides H Heemskerk, B Aguilera, A Janson, KH Pang, GJ van Ommen, ... Journal of Controlled Release 132 (3), e3-e5, 2008 | 3 | 2008 |
| Systemic Antisense-Mediated Exon Skipping in Mouse Models for Duchenne Muscular Dystrophy A Aartsma-Rus, H Heemskerk, C De Winter, M Van Putten, A Janson, ... NATURE PUBLISHING GROUP 17, S166-S166, 2009 | 1 | 2009 |
| O. 12 Peptide-enhanced uptake and bioactivity of antisense oligonucleotides in muscle and heart of DMD and DM1 mouse models B Aguilera, SAM Mulders, C Tanganyika-de Winter, WJA van den Broek, ... Neuromuscular Disorders 23 (9), 848, 2013 | | 2013 |
| TP 26 Low dystrophin levels increase survival and improve pathology and motor function in dystrophin/utrophin double knockout mice M van Putten, M Hulsker, C Young, VD Nadarajah, H Heemskerk, ... Neuromuscular Disorders 22 (9), 860, 2012 | | 2012 |
| Identification of Peptides for Tissue-Specific Delivery H Heemskerk Exon Skipping: Methods and Protocols, 379-392, 2012 | | 2012 |
| European Society of Gene and Cell Therapy British Society for Gene Therapy Collaborative Congress 2011 October 27–31, 2011 The Brighton Centre, Brighton United Kingdom LW Seymour, M Antoniou, DRP Harbottle, C Denning, R Hajjar, S Ferber, ... Human Gene Therapy 22 (10), A1-A138, 2011 | | 2011 |
| SFTCG 2009 Invited Presentations R Jaenisch, M Pucéat, E Charafe-Jauffret, C Ginestier, F Iovino, ... Human Gene Therapy 20 (6), 657-664, 2009 | | 2009 |
