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Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy RL Vidal, A Figueroa, FA Court, P Thielen, C Molina, C Wirth, B Caballero, ... Human molecular genetics 21 (10), 2245-2262, 2012 | 271 | 2012 |
Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells Y Hu, KK Park, L Yang, X Wei, Q Yang, KS Cho, P Thielen, AH Lee, ... Neuron 73 (3), 445-452, 2012 | 212 | 2012 |
IRE1 signaling exacerbates Alzheimer’s disease pathogenesis C Duran-Aniotz, VH Cornejo, S Espinoza, ÁO Ardiles, DB Medinas, ... Acta neuropathologica 134, 489-506, 2017 | 211 | 2017 |
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Regulation of memory formation by the transcription factor XBP1 G Martínez, RL Vidal, P Mardones, FG Serrano, AO Ardiles, C Wirth, ... Cell reports 14 (6), 1382-1394, 2016 | 182 | 2016 |
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The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis C Hetz, P Thielen, J Fisher, P Pasinelli, RH Brown, S Korsmeyer, ... Cell Death & Differentiation 14 (7), 1386-1389, 2007 | 88 | 2007 |
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Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates P García-Huerta, P Troncoso-Escudero, D Wu, A Thiruvalluvan, ... Acta neuropathologica 140, 737-764, 2020 | 55 | 2020 |
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Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo AD Steele, OD King, WS Jackson, CA Hetz, AW Borkowski, P Thielen, ... Journal of Neuroscience 27 (47), 13022-13027, 2007 | 47 | 2007 |
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