| Lactate metabolism in human lung tumors B Faubert, KY Li, L Cai, CT Hensley, J Kim, LG Zacharias, C Yang, QN Do, ... Cell 171 (2), 358-371. e9, 2017 | 1130 | 2017 |
| Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes L Cai, BM Sutter, B Li, BP Tu Molecular cell 42 (4), 426-437, 2011 | 742 | 2011 |
| Acetate dependence of tumors SA Comerford, Z Huang, X Du, Y Wang, L Cai, AK Witkiewicz, H Walters, ... Cell 159 (7), 1591-1602, 2014 | 657 | 2014 |
| Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo I Marin-Valencia, C Yang, T Mashimo, S Cho, H Baek, XL Yang, ... Cell metabolism 15 (6), 827-837, 2012 | 548 | 2012 |
| CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ... Nature 546 (7656), 168-172, 2017 | 277 | 2017 |
| Comprehensive analysis of lung cancer pathology images to discover tumor shape and boundary features that predict survival outcome S Wang, A Chen, L Yang, L Cai, Y Xie, J Fujimoto, A Gazdar, G Xiao Scientific reports 8 (1), 10393, 2018 | 214 | 2018 |
| Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ... Cell metabolism 28 (3), 369-382. e5, 2018 | 173 | 2018 |
| Driving the cell cycle through metabolism L Cai, BP Tu Annual review of cell and developmental biology 28 (1), 59-87, 2012 | 157 | 2012 |
| Metabolic diversity in human non-small cell lung cancer cells PH Chen, L Cai, K Huffman, C Yang, J Kim, B Faubert, L Boroughs, B Ko, ... Molecular cell 76 (5), 838-851. e5, 2019 | 152 | 2019 |
| ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism BPT Zhiguang Huang, Menglu Zhang, Abigail A. Plec, Sandi Jo Estill, Ling Cai ... Proc Natl Acad Sci U S A 115 (40), E9499-E9506, 2018 | 130* | 2018 |
| Computational staining of pathology images to study the tumor microenvironment in lung cancer S Wang, R Rong, DM Yang, J Fujimoto, S Yan, L Cai, L Yang, D Luo, ... Cancer research 80 (10), 2056-2066, 2020 | 113 | 2020 |
| On acetyl-CoA as a gauge of cellular metabolic state L Cai, BP Tu Cold Spring Harbor symposia on quantitative biology 76, 195-202, 2011 | 103 | 2011 |
| LCE: an open web portal to explore gene expression and clinical associations in lung cancer L Cai, SY Lin, L Girard, Y Zhou, L Yang, B Ci, Q Zhou, D Luo, B Yao, ... Oncogene 38 (14), 2551-2564, 2019 | 96 | 2019 |
| The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer J Kim, HM Lee, F Cai, B Ko, C Yang, EL Lieu, N Muhammad, S Rhyne, ... Nature metabolism 2 (12), 1401-1412, 2020 | 95 | 2020 |
| TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer K Gong, G Guo, DE Gerber, B Gao, M Peyton, C Huang, JD Minna, ... The Journal of clinical investigation 128 (6), 2500-2518, 2018 | 92 | 2018 |
| High-temporal-resolution view of transcription and chromatin states across distinct metabolic states in budding yeast Z Kuang, L Cai, X Zhang, H Ji, B Tu, J Boeke NATURE STRUCTURAL & MOLECULAR BIOLOGY 21, 854–863, 2014 | 91 | 2014 |
| Functional assessment of lipoyltransferase-1 deficiency in cells, mice, and humans M Ni, A Solmonson, C Pan, C Yang, D Li, A Notzon, L Cai, G Guevara, ... Cell reports 27 (5), 1376-1386. e6, 2019 | 76 | 2019 |
| Compartmentalized metabolism supports midgestation mammalian development A Solmonson, B Faubert, W Gu, A Rao, MA Cowdin, I Menendez-Montes, ... Nature 604 (7905), 349-353, 2022 | 72 | 2022 |
| Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export L Zhang, P Das, M Schmolke, B Manicassamy, Y Wang, X Deng, L Cai, ... Journal of Cell Biology 196 (3), 315-326, 2012 | 68 | 2012 |
| Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer L Cai, H Liu, F Huang, J Fujimoto, L Girard, J Chen, Y Li, YA Zhang, ... Communications Biology 4 (1), 314, 2021 | 57 | 2021 |
Ralph DeBerardinisDirector, McDermott Center for Human Growth and Development, UT SouthwesternVerified email at utsouthwestern.edu
