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Jesse D. Bloom
Jesse D. Bloom
Fred Hutch Cancer Center; University of Washington; Howard Hughes Medical Institute
Verified email at fredhutch.org - Homepage
Title
Cited by
Cited by
Year
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
cell 182 (5), 1295-1310. e20, 2020
18242020
Protein stability promotes evolvability
JD Bloom, ST Labthavikul, CR Otey, FH Arnold
Proceedings of the National Academy of Sciences 103 (15), 5869-5874, 2006
12892006
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
Cell host & microbe 29 (3), 463-476. e6, 2021
11832021
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
10362021
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
8902005
Permissive secondary mutations enable the evolution of influenza oseltamivir resistance
JD Bloom, LI Gong, D Baltimore
Science 328 (5983), 1272-1275, 2010
7352010
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
7312021
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays
KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, ...
Viruses 12 (5), 513, 2020
7102020
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate
A Addetia, KHD Crawford, A Dingens, H Zhu, P Roychoudhury, ML Huang, ...
Journal of clinical microbiology 58 (11), 10.1128/jcm. 02107-20, 2020
5942020
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020
EB Hodcroft, M Zuber, S Nadeau, TG Vaughan, KHD Crawford, ...
Nature 595 (7869), 707-712, 2021
5712021
In the light of directed evolution: pathways of adaptive protein evolution
JD Bloom, FH Arnold
Proceedings of the National Academy of Sciences 106 (supplement_1), 9995-10000, 2009
5442009
Evolving strategies for enzyme engineering
JD Bloom, MM Meyer, P Meinhold, CR Otey, D MacMillan, FH Arnold
Current opinion in structural biology 15 (4), 447-452, 2005
4672005
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 2021
4622021
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
3922005
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
3882021
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ...
Nature communications 12 (1), 4196, 2021
376*2021
Stability-mediated epistasis constrains the evolution of an influenza protein
LI Gong, MA Suchard, JD Bloom
Elife 2, e00631, 2013
3632013
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature microbiology 6 (10), 1233-1244, 2021
357*2021
Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection
KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ...
The Journal of infectious diseases 223 (2), 197-205, 2021
2922021
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
2272012
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Articles 1–20