Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells Y Gao, SA Nish, R Jiang, L Hou, P Licona-Limón, JS Weinstein, H Zhao, ... Immunity 39 (4), 722-732, 2013 | 519 | 2013 |
Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells EF Foxman, JA Storer, ME Fitzgerald, BR Wasik, L Hou, H Zhao, ... Proceedings of the National Academy of Sciences 112 (3), 827-832, 2015 | 285 | 2015 |
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ... Genome biology 15 (3), 1-18, 2014 | 125 | 2014 |
A review of post-GWAS prioritization approaches L Hou, H Zhao Frontiers in genetics 4, 280, 2013 | 118 | 2013 |
A Multipurpose, High-Throughput Single-Nucleotide Polymorphism Chip for the Dengue and Yellow Fever Mosquito, Aedes aegypti BR Evans, A Gloria-Soria, L Hou, C McBride, M Bonizzoni, H Zhao, ... G3: Genes, Genomes, Genetics 5 (5), 711-718, 2015 | 73 | 2015 |
Guilt by rewiring: gene prioritization through network rewiring in genome wide association studies L Hou, M Chen, CK Zhang, J Cho, H Zhao Human molecular genetics 23 (10), 2780-2790, 2014 | 64 | 2014 |
Identification of trans-eQTLs using mediation analysis with multiple mediators N Shan, Z Wang, L Hou BMC bioinformatics 20 (3), 87-97, 2019 | 55 | 2019 |
Cell type annotation of single-cell chromatin accessibility data via supervised Bayesian embedding X Chen, S Chen, S Song, Z Gao, L Hou, X Zhang, H Lv, R Jiang Nature Machine Intelligence 4 (2), 116-126, 2022 | 54 | 2022 |
Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition Y Xie, Y Jin, BL Merenick, M Ding, KM Fetalvero, RJ Wagner, A Mai, ... Science signaling 8 (376), ra44-ra44, 2015 | 54 | 2015 |
Leveraging effect size distributions to improve polygenic risk scores derived from summary statistics of genome-wide association studies S Song, W Jiang, L Hou, H Zhao PLOS Computational Biology 16 (2), e1007565, 2020 | 45 | 2020 |
Detecting local genetic correlations with scan statistics H Guo, JJ Li, Q Lu, L Hou Nature communications 12 (1), 1-13, 2021 | 42 | 2021 |
Global COVID-19 pandemic demands joint interventions for the suppression of future waves R Li, B Chen, T Zhang, Z Ren, Y Song, Y Xiao, L Hou, J Cai, B Xu, M Li, ... Proceedings of the National Academy of Sciences 117 (42), 26151-26157, 2020 | 39 | 2020 |
A set of efficient methods to generate high-dimensional binary data with specified correlation structures W Jiang, S Song, L Hou, H Zhao The American Statistician 75 (3), 310-322, 2021 | 36 | 2021 |
Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes M Liu, J Peng, N Tai, JA Pearson, C Hu, J Guo, L Hou, H Zhao, FS Wong, ... Diabetologia 61 (11), 2333-2343, 2018 | 35 | 2018 |
Systematic identification of conserved motif modules in the human genome X Cai, L Hou, N Su, H Hu, M Deng, X Li BMC genomics 11 (1), 1-10, 2010 | 34 | 2010 |
Classification of non-small cell lung cancer’s tumor immune micro-environment and strategies to augment its response to immune checkpoint blockade A Chi, X He, L Hou, NP Nguyen, G Zhu, RB Cameron, JM Lee Cancers 13 (12), 2924, 2021 | 28 | 2021 |
Computational identification of rare codons of Escherichia coli based on codon pairs preference X Wu, S Wu, D Li, J Zhang, L Hou, J Ma, W Liu, D Ren, Y Zhu, F He Bmc Bioinformatics 11 (1), 1-8, 2010 | 28 | 2010 |
Interplay of tRNA-derived fragments and T cell activation in breast cancer patient survival N Shan, N Li, Q Dai, L Hou, X Yan, A Amei, L Lu, Z Wang Cancers 12 (8), 2230, 2020 | 26 | 2020 |
Evidence for the additions of clustered interacting nodes during the evolution of protein interaction networks from network motifs Z Liu, Q Liu, H Sun, L Hou, H Guo, Y Zhu, D Li, F He BMC Evolutionary Biology 11 (1), 1-12, 2011 | 26 | 2011 |
Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells AMB Tadeu, S Lin, L Hou, L Chung, M Zhong, H Zhao, V Horsley PLoS One 10 (4), e0122493, 2015 | 24 | 2015 |