Malignant astrocytic glioma: genetics, biology, and paths to treatment FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ... Genes & development 21 (21), 2683-2710, 2007 | 2936 | 2007 |
Malignant glioma: genetics and biology of a grave matter EA Maher, FB Furnari, RM Bachoo, DH Rowitch, DN Louis, WK Cavenee, ... Genes & development 15 (11), 1311-1333, 2001 | 1575 | 2001 |
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth T Gao, F Furnari, AC Newton Molecular cell 18 (1), 13-24, 2005 | 1142 | 2005 |
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity KM Turner, V Deshpande, D Beyter, T Koga, J Rusert, C Lee, B Li, ... Nature 543 (7643), 122-125, 2017 | 675 | 2017 |
Emerging insights into the molecular and cellular basis of glioblastoma GP Dunn, ML Rinne, J Wykosky, G Genovese, SN Quayle, IF Dunn, ... Genes & development 26 (8), 756-784, 2012 | 674 | 2012 |
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting JC Sok, FM Coppelli, SM Thomas, MN Lango, S Xi, JL Hunt, ML Freilino, ... Clinical Cancer Research 12 (17), 5064-5073, 2006 | 633 | 2006 |
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA DA Nathanson, B Gini, J Mottahedeh, K Visnyei, T Koga, G Gomez, ... Science 343 (6166), 72-76, 2014 | 611 | 2014 |
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma R Bonavia, A Mukasa, Y Narita, DWY Sah, S Vandenberg, C Brennan, ... Genes & development 24 (16), 1731-1745, 2010 | 610 | 2010 |
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain FB Furnari, H Lin, HJS Huang, WK Cavenee Proceedings of the National Academy of Sciences 94 (23), 12479-12484, 1997 | 595 | 1997 |
The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells FB Furnari, HJS Huang, WK Cavenee Cancer research 58 (22), 5002-5008, 1998 | 591 | 1998 |
Heterogeneity maintenance in glioblastoma: a social network R Bonavia, MM Inda, WK Cavenee, FB Furnari Cancer research 71 (12), 4055-4060, 2011 | 541 | 2011 |
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma PH Huang, A Mukasa, R Bonavia, RA Flynn, ZE Brewer, WK Cavenee, ... Proceedings of the National Academy of Sciences 104 (31), 12867-12872, 2007 | 479 | 2007 |
Circular ecDNA promotes accessible chromatin and high oncogene expression S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ... Nature 575 (7784), 699-703, 2019 | 443 | 2019 |
Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma FB Furnari, TF Cloughesy, WK Cavenee, PS Mischel Nature Reviews Cancer 15 (5), 302-310, 2015 | 398 | 2015 |
Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cell 160 (3), 489-502, 2015 | 359 | 2015 |
Dynamics of centromere and kinetochore proteins: implications for checkpoint signaling and silencing JV Shah, E Botvinick, Z Bonday, F Furnari, M Berns, DW Cleveland Current biology 14 (11), 942-952, 2004 | 345 | 2004 |
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma B Mukherjee, B McEllin, CV Camacho, N Tomimatsu, S Sirasanagandala, ... Cancer research 69 (10), 4252-4259, 2009 | 326 | 2009 |
Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance T E Taylor, F B Furnari, W K Cavenee Current cancer drug targets 12 (3), 197-209, 2012 | 311 | 2012 |
PCAF Modulates PTEN Activity*♦ K Okumura, M Mendoza, RM Bachoo, RA DePinho, WK Cavenee, ... Journal of Biological Chemistry 281 (36), 26562-26568, 2006 | 291 | 2006 |
An LXR-cholesterol axis creates a metabolic co-dependency for brain cancers GR Villa, JJ Hulce, C Zanca, J Bi, S Ikegami, GL Cahill, Y Gu, KM Lum, ... Cancer cell 30 (5), 683-693, 2016 | 290 | 2016 |