Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults KL Kalantar, L Neyton, M Abdelghany, E Mick, A Jauregui, S Caldera, ... Nature microbiology 7 (11), 1805-1816, 2022 | 45 | 2022 |
Molecular patterns in acute pancreatitis reflect generalizable endotypes of the host response to systemic injury in humans L Neyton, X Zheng, C Skouras, A Doeschl-Wilson, MU Gutmann, I Uings, ... Annals of surgery 275 (2), e453-e462, 2022 | 29* | 2022 |
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study JE Millar, L Neyton, S Seth, J Dunning, L Merson, S Murthy, CD Russell, ... Scientific Reports 12 (1), 6843, 2022 | 28* | 2022 |
Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials P Sinha, VE Kerchberger, A Willmore, J Chambers, H Zhuo, J Abbott, ... The Lancet Respiratory Medicine, 2023 | 27 | 2023 |
Characterizing preclinical sub‐phenotypic models of acute respiratory distress syndrome: An experimental ovine study JE Millar, K Wildi, N Bartnikowski, M Bouquet, K Hyslop, MR Passmore, ... Physiological reports 9 (19), e15048, 2021 | 18 | 2021 |
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease JK Baillie, A Bretherick, CS Haley, S Clohisey, A Gray, LPA Neyton, ... PLoS computational biology 14 (3), e1005934, 2018 | 18 | 2018 |
Quantitative magnetic resonance imaging predicts individual future liver performance after liver resection for cancer DJ Mole, JA Fallowfield, AE Sherif, T Kendall, S Semple, M Kelly, ... PLoS One 15 (12), e0238568, 2020 | 14 | 2020 |
Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS N Alipanah-Lechner, L Neyton, E Mick, A Willmore, A Leligdowicz, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 324 (3 …, 2023 | 12 | 2023 |
Metagenomic Sequencing in the ICU for Precision Diagnosis of Critical Infectious Illnesses LPA Neyton, CR Langelier, CS Calfee Critical Care 27 (1), 90, 2023 | 6 | 2023 |
Metabolic signatures of ARDS and ARDS heterogeneity L Neyton, CS Calfee American Journal of Physiology-Lung Cellular and Molecular Physiology 321 (6 …, 2021 | 4 | 2021 |
Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes LPA Neyton, P Sinha, A Sarma, E Mick, K Kalantar, S Chen, N Wu, ... American Journal of Respiratory and Critical Care Medicine, 2024 | 3 | 2024 |
Molecular Phenotypes of ARDS in the ROSE Trial have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally Over Time P Sinha, L Neyton, A Sarma, N Wu, C Jones, H Zhuo, KD Liu, ... American Journal of Respiratory and Critical Care Medicine, 2024 | 2 | 2024 |
Plasma metabolic profiles of hyperinflammatory and hypoinflammatory ARDS may implicate glycolytic shift N Alipanah-Lechner, E Mick, LPA Neyton, A Willmore, A Leligdowicz, ... C104. CHANGE IS HAPPENING AT A RAPID RATE: ARDS AND MECHANICAL VENTILATION …, 2022 | 2 | 2022 |
Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis AJ Hayes, X Zheng, J O’Kelly, LPA Neyton, NA Bochkina, I Uings, J Liddle, ... Cell Reports 42 (8), 2023 | 1 | 2023 |
Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19 G Fragiadakis, L Neyton, R Patel, A Sarma, A Willmore, SC Haller, ... | 1* | 2023 |
Latent Class Analysis-Derived Hypoinflammatory and Hyperinflammatory Phenotypes Are Generalisable to Sepsis Patients Requiring Intensive Care P Sinha, J He, K Delucchi, H Zhuo, J Abbott, C Jones, N Wickersham, ... B95. ARDS: WHAT'S THE LATEST AND GREATEST?, A3431-A3431, 2022 | 1 | 2022 |
Distinct respiratory tract biological pathways characterizing ARDS molecular phenotypes A Sarma, SA Christenson, BS Zha, AO Pisco, LPA Neyton, E Mick, ... medRxiv, 2022.03. 31.22272425, 2022 | 1 | 2022 |
Rapidly Improving Acute Respiratory Distress Syndrome: Clinical and Biologic Features P Valda Toro, A Willmore, N Wu, KL Delucchi, A Jauregui, P Sinha, K Liu, ... B103. PERSONALIZING CARE FOR PATIENTS WITH ACUTE RESPIRATORY FAILURE, A4794 …, 2024 | | 2024 |
Elastance Is an Important Modifier of the Effect of Neuromuscular Blockade on Mortality in Patients With Acute Respiratory Distress Syndrome A Zalucky, J Dianti, LPA Neyton, P Sinha, EC Goligher, K Liu, MA Matthay, ... C96. PRECISION MEDICINE IN CRITICAL CARE: EXPLORING ARDS AND SEPSIS …, 2024 | | 2024 |
Rapidly improving ARDS differs clinically and biologically from persistent ARDS PL Valda Toro, A Willmore, NE Wu, KL Delucchi, A Jauregui, P Sinha, ... Critical Care 28 (1), 132, 2024 | | 2024 |