| Stromal fibroblasts in cancer initiation and progression NA Bhowmick, EG Neilson, HL Moses Nature 432 (7015), 332-337, 2004 | 3017 | 2004 |
| TGF-ß signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia NA Bhowmick, A Chytil, D Plieth, AE Gorska, N Dumont, S Shappell, ... Science 303 (5659), 848-851, 2004 | 1673 | 2004 |
| Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism NA Bhowmick, M Ghiassi, A Bakin, M Aakre, CA Lundquist, ME Engel, ... Molecular biology of the cell 12 (1), 27-36, 2001 | 1376 | 2001 |
| Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration AV Bakin, AK Tomlinson, NA Bhowmick, HL Moses, CL Arteaga Journal of Biological Chemistry 275 (47), 36803-36810, 2000 | 1202 | 2000 |
| Tumor–stroma interactions NA Bhowmick, HL Moses Current opinion in genetics & development 15 (1), 97-101, 2005 | 592 | 2005 |
| Integrin β1 signaling is necessary for transforming growth factor-β activation of p38MAPK and epithelial plasticity NA Bhowmick, R Zent, M Ghiassi, M McDonnell, HL Moses Journal of Biological Chemistry 276 (50), 46707-46713, 2001 | 520 | 2001 |
| Role of EMT in metastasis and therapy resistance BN Smith, NA Bhowmick Journal of clinical medicine 5 (2), 17, 2016 | 518 | 2016 |
| Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease D Di Vizio, M Morello, AC Dudley, PW Schow, RM Adam, S Morley, ... The American journal of pathology 181 (5), 1573-1584, 2012 | 418 | 2012 |
| Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP-and HGF-mediated signaling networks N Cheng, NA Bhowmick, A Chytil, AE Gorksa, KA Brown, R Muraoka, ... Oncogene 24 (32), 5053-5068, 2005 | 339 | 2005 |
| Essential role of Smad3 in angiotensin II–induced vascular fibrosis W Wang, XR Huang, E Canlas, K Oka, LD Truong, C Deng, NA Bhowmick, ... Circulation research 98 (8), 1032-1039, 2006 | 296 | 2006 |
| Large oncosomes mediate intercellular transfer of functional microRNA M Morello, V Minciacchi, P de Candia, J Yang, E Posadas, H Kim, ... Cell cycle 12 (22), 3526-3536, 2013 | 242 | 2013 |
| The nuclear factor-κB pathway controls the progression of prostate cancer to androgen-independent growth RJ Jin, Y Lho, L Connelly, Y Wang, X Yu, L Saint Jean, TC Case, ... Cancer research 68 (16), 6762-6769, 2008 | 224 | 2008 |
| Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis OE Franco, M Jiang, DW Strand, J Peacock, S Fernandez, RS Jackson, ... Cancer research 71 (4), 1272-1281, 2011 | 206 | 2011 |
| Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis X Li, V Placencio, JM Iturregui, C Uwamariya, AR Sharif-Afshar, T Koyama, ... Oncogene 27 (56), 7118-7130, 2008 | 183 | 2008 |
| Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line L Xie, BK Law, ME Aakre, M Edgerton, Y Shyr, NA Bhowmick, HL Moses Breast Cancer Research 5, 1-12, 2003 | 182 | 2003 |
| Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-β receptor exhibit impaired mammary development and enhanced mammary tumor formation AE Gorska, RA Jensen, Y Shyr, ME Aakre, NA Bhowmick, HL Moses The American journal of pathology 163 (4), 1539-1549, 2003 | 174 | 2003 |
| TGF-β-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest NA Bhowmick, M Ghiassi, M Aakre, K Brown, V Singh, HL Moses Proceedings of the National Academy of Sciences 100 (26), 15548-15553, 2003 | 166 | 2003 |
| Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and … N Bhowmick, J Huang, D Puett, NW Isaacs, AJ Lapthorn Molecular Endocrinology 10 (9), 1147-1159, 1996 | 163 | 1996 |
| The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity J Qi, M Tripathi, R Mishra, N Sahgal, L Fazil, S Ettinger, WJ Placzek, ... Cancer cell 23 (3), 332-346, 2013 | 156 | 2013 |
| MYC mediates large oncosome-induced fibroblast reprogramming in prostate cancer VR Minciacchi, C Spinelli, M Reis-Sobreiro, L Cavallini, S You, M Zandian, ... Cancer research 77 (9), 2306-2317, 2017 | 139 | 2017 |
Edwin PosadasMedical Director, Urologic Oncology Program; Director, Translational Oncology Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical CenterVerified email at csmc.edu
