Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ... MAbs 12 (1), 1770669, 2020 | 59 | 2020 |
Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media J Xu, MS Rehmann, X Xu, C Huang, J Tian, NX Qian, ZJ Li MAbs 10 (3), 488-499, 2018 | 57 | 2018 |
Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study J Xu, M Jin, H Song, C Huang, X Xu, J Tian, NX Qian, K Steger, NS Lewen, ... Process Biochemistry 49 (1), 130-139, 2014 | 41 | 2014 |
Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification W Jin, Z Xing, Y Song, C Huang, X Xu, S Ghose, ZJ Li MAbs 11 (8), 1479-1491, 2019 | 40 | 2019 |
Synthesis and labeling of RNA in vitro C Huang, YT Yu Current protocols in molecular biology 102 (1), 4.15. 1-4.15. 14, 2013 | 40 | 2013 |
Inducing nonsense suppression by targeted pseudouridylation C Huang, G Wu, YT Yu nature protocols 7 (4), 789-800, 2012 | 26 | 2012 |
Investigation of color in a fusion protein using advanced analytical techniques: delineating contributions from oxidation products and process related impurities H Song, J Xu, M Jin, C Huang, J Bongers, H Bai, W Wu, R Ludwig, Z Li, ... Pharmaceutical research 33, 932-941, 2016 | 25 | 2016 |
Non-catalytic domains of subunit A negatively regulate the activity of calcineurin P Liu, C Huang, Z Jia, F Yi, D Yu, Q Wei Biochimie 87 (2), 215-221, 2005 | 25 | 2005 |
DNA retention on depth filters O Khanal, X Xu, N Singh, SJ Traylor, C Huang, S Ghose, ZJ Li, ... Journal of membrane science 570, 464-471, 2019 | 24 | 2019 |
Targeted 2′-O Methylation at a Nucleotide within the Pseudoknot of Telomerase RNA Reduces Telomerase Activity In Vivo C Huang, YT Yu Molecular and cellular biology 30 (18), 4368-4378, 2010 | 23 | 2010 |
The importance of Loop 7 for the activity of calcineurin P Liu, C Huang, H Wang, K Zhou, F Xiao, W Qun FEBS letters 577 (1-2), 205-208, 2004 | 21 | 2004 |
Detection and quantification of RNA 2′-O-methylation and pseudouridylation C Huang, J Karijolich, YT Yu Methods 103, 68-76, 2016 | 19 | 2016 |
Post-transcriptional modification of RNAs by artificial Box H/ACA and Box C/D RNPs C Huang, J Karijolich, YT Yu RNA and DNA Editing: Methods and Protocols, 227-244, 2011 | 19 | 2011 |
Pseudouridine in mRNA: incorporation, detection, and recoding G Wu, C Huang, YT Yu Methods in enzymology 560, 187-217, 2015 | 16 | 2015 |
Different roles of Loop 7 in inhibition of calcineurin H Wang, S Yao, W Lin, Y Du, B Xiang, S He, C Huang, Q Wei Biochemical and biophysical research communications 362 (2), 263-268, 2007 | 15 | 2007 |
Insights in understanding aggregate formation and dissociation in cation exchange chromatography for a structurally unstable Fc-fusion protein Z Chen, C Huang, N Chennamsetty, X Xu, ZJ Li Journal of Chromatography A 1460, 110-122, 2016 | 14 | 2016 |
Hydrophobic property of cation-exchange resins affects monoclonal antibody aggregation C Huang, Y Wang, X Xu, J Mills, W Jin, S Ghose, ZJ Li Journal of Chromatography A 1631, 461573, 2020 | 5 | 2020 |
Spliceosomal snRNA pseudouridylation J Karijolich, C Huang, YT Yu DNA and RNA Modification Enzymes: Structure, Mechanism, Function and …, 2009 | 4 | 2009 |
A CFD model for predicting protein aggregation in low‐pH virial inactivation for mAb production Z Xing, W Jin, X Xu, Y Song, C Huang, MC Borys, S Ghose, ZJ Li Biotechnology and Bioengineering 117 (11), 3400-3412, 2020 | 3 | 2020 |
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: A case study. mAbs, 12 (1): 1770669 J Xu, X Xu, C Huang, J Angelo, CL Oliveira, M Xu, X Xu, D Temel, J Ding, ... | 3 | 2020 |