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Srinivasa P S Rao
Srinivasa P S Rao
Novartis Institute for Tropical Diseases
Verified email at novartis.com
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Cited by
Year
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ...
Nature medicine 19 (9), 1157-1160, 2013
6032013
The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
SPS Rao, S Alonso, L Rand, T Dick, K Pethe
Proceedings of the National Academy of Sciences 105 (33), 11945-11950, 2008
6022008
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
S Khare, AS Nagle, A Biggart, YH Lai, F Liang, LC Davis, SW Barnes, ...
Nature 537 (7619), 229-233, 2016
3972016
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy
K Pethe, PC Sequeira, S Agarwalla, K Rhee, K Kuhen, WY Phong, V Patel, ...
Nature communications 1 (1), 57, 2010
3142010
Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and …
M Gengenbacher, SPS Rao, K Pethe, T Dick
Microbiology 156 (1), 81-87, 2010
3082010
Use of proteomics to identify novel virulence determinants that are required for Edwardsiella tarda pathogenesis
PS Srinivasa Rao, Y Yamada, YP Tan, KY Leung
Molecular microbiology 53 (2), 573-586, 2004
2752004
The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease
EK Schmitt, M Riwanto, V Sambandamurthy, S Roggo, C Miault, ...
Angewandte Chemie International Edition 26 (50), 5889-5891, 2011
2032011
Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis
S Hasan, S Daugelat, PSS Rao, M Schreiber
PLoS computational biology 2 (6), e61, 2006
1862006
Opsonized Virulent Edwardsiella tarda Strains Are Able To Adhere to and Survive and Replicate within Fish Phagocytes but Fail To Stimulate Reactive Oxygen …
PSS Rao, TM Lim, KY Leung
Infection and immunity 69 (9), 5689-5697, 2001
1852001
A Type III Secretion System Is Required for Aeromonas hydrophila AH-1 Pathogenesis
HB Yu, PSS Rao, HC Lee, S Vilches, S Merino, JM Tomas, KY Leung
Infection and immunity 72 (3), 1248-1256, 2004
1722004
Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis
SPS Rao, SB Lakshminarayana, RR Kondreddi, M Herve, LR Camacho, ...
Science translational medicine 5 (214), 214ra168-214ra168, 2013
1642013
Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents
SB Lakshminarayana, TB Huat, PC Ho, UH Manjunatha, V Dartois, T Dick, ...
Journal of Antimicrobial Chemotherapy 70 (3), 857-867, 2015
1552015
Functional Genomics Approach to the Identification of Virulence Genes Involved in Edwardsiella tarda Pathogenesis
PS Srinivasa Rao, TM Lim, KY Leung
Infection and Immunity 71 (3), 1343-1351, 2003
1512003
Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin
KL Low, PSS Rao, G Shui, AK Bendt, K Pethe, T Dick, MR Wenk
Journal of bacteriology 191 (16), 5037-5043, 2009
1482009
A major catalase (KatB) that is required for resistance to H2O2 and phagocyte-mediated killing in Edwardsiella tarda
PS Srinivasa Rao, Y Yamada, KY Leung
Microbiology 149 (9), 2635-2644, 2003
1412003
The effectiveness of a commercial microbial product in poorly prepared tiger shrimp, Penaeus monodon (Fabricius), ponds
M Shariff, FM Yusoff, TN Devaraja, PSS Rao
Aquaculture Research 32 (3), 181-187, 2001
1412001
A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis
PA Mak, SPS Rao, M Ping Tan, X Lin, J Chyba, J Tay, SH Ng, BH Tan, ...
ACS chemical biology 7 (7), 1190-1197, 2012
1332012
Structural basis of mycobacterial inhibition by cyclomarin A
D Vasudevan, SPS Rao, CG Noble
Journal of Biological Chemistry 288 (43), 30883-30891, 2013
1282013
Structural Basis of Mycobacterial Inhibition by Cyclomarin A
D Vasudevan, SPS Rao, CG Noble
Journal of Biological Chemistry, 2013
1282013
Direct inhibitors of InhA are active against Mycobacterium tuberculosis
UH Manjunatha, SP S. Rao, RR Kondreddi, CG Noble, LR Camacho, ...
Science translational medicine 7 (269), 269ra3-269ra3, 2015
1222015
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