Nicholas J. Bradshaw
Nicholas J. Bradshaw
Department of Biotechnology, University of Rijeka, Croatia
Verified email at
Cited by
Cited by
The DISC locus in psychiatric illness
JE Chubb, NJ Bradshaw, DC Soares, DJ Porteous, JK Millar
Molecular psychiatry 13 (1), 36-64, 2008
DISC1-binding proteins in neural development, signalling and schizophrenia
NJ Bradshaw, DJ Porteous
Neuropharmacology 62 (3), 1230-1241, 2012
DISC1: structure, function, and therapeutic potential for major mental illness
DC Soares, BC Carlyle, NJ Bradshaw, DJ Porteous
ACS chemical neuroscience 2 (11), 609-632, 2011
DISC1, PDE4B, and NDE1 at the centrosome and synapse
NJ Bradshaw, F Ogawa, B Antolin-Fontes, JE Chubb, BC Carlyle, ...
Biochemical and biophysical research communications 377 (4), 1091-1096, 2008
PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1
NJ Bradshaw, DC Soares, BC Carlyle, F Ogawa, H Davidson-Smith, ...
Journal of Neuroscience 31 (24), 9043-9054, 2011
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious …
JE Eykelenboom, GJ Briggs, NJ Bradshaw, DC Soares, F Ogawa, ...
Human molecular genetics 21 (15), 3374-3386, 2012
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits
V Bader, L Tomppo, SV Trossbach, NJ Bradshaw, I Prikulis, SR Leliveld, ...
Human molecular genetics 21 (20), 4406-4418, 2012
Recent and Recurrent Selective Sweeps of the Antiviral RNAi Gene Argonaute-2 in Three Species of Drosophila
DJ Obbard, FM Jiggins, NJ Bradshaw, TJ Little
Molecular biology and evolution 28 (2), 1043-1056, 2011
NDE1 and NDEL1 from genes to (mal) functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness
NJ Bradshaw, MAF Hayashi
Cellular and molecular life sciences 74, 1191-1210, 2017
NDE1 and NDEL1: twin neurodevelopmental proteins with similar ‘nature’but different ‘nurture’
NJ Bradshaw, W Hennah, DC Soares
Biomolecular concepts 4 (5), 447-464, 2013
Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness
NJ Bradshaw, C Korth
Molecular psychiatry 24 (7), 936-951, 2019
NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction
NJ Bradshaw, S Christie, DC Soares, BC Carlyle, DJ Porteous, JK Millar
Neuroscience letters 449 (3), 228-233, 2009
Revisiting disrupted-in-schizophrenia 1 as a scaffold protein
ASK Yerabham, OH Weiergräber, NJ Bradshaw, C Korth
Biological chemistry 394 (11), 1425-1437, 2013
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution
DC Soares, NJ Bradshaw, J Zou, CK Kennaway, RS Hamilton, ZA Chen, ...
Journal of Biological Chemistry 287 (39), 32381-32393, 2012
Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia
NJ Bradshaw, V Bader, I Prikulis, A Lueking, S Müllner, C Korth
PloS one 9 (10), e111196, 2014
A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental …
ASK Yerabham, PJ Mas, C Decker, DC Soares, OH Weiergräber, ...
Journal of Biological Chemistry 292 (16), 6468-6477, 2017
An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure
NJ Bradshaw, ASK Yerabham, R Marreiros, T Zhang, L Nagel-Steger, ...
Journal of Biological Chemistry 292 (23), 9583-9598, 2017
Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions
NS Gowert, I Krüger, M Klier, L Donner, F Kipkeew, M Gliem, ...
Cellular Signalling 40, 210-221, 2017
The TRIOBP isoforms and their distinct roles in actin stabilization, deafness, mental illness, and cancer
B Zaharija, B Samardžija, NJ Bradshaw
Molecules 25 (21), 4967, 2020
The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484
NJ Bradshaw, L Ukkola-Vuoti, M Pankakoski, AB Zheutlin, ...
Open biology 7 (11), 170153, 2017
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