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Xueliang Yu
Xueliang Yu
Bestätigte E-Mail-Adresse bei utsouthwestern.edu
Titel
Zitiert von
Zitiert von
Jahr
Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing
S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart
Nature materials 20 (5), 701-710, 2021
2942021
Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy
D Zhang, G Wang, X Yu, T Wei, L Farbiak, LT Johnson, AM Taylor, J Xu, ...
Nature nanotechnology 17 (7), 777-787, 2022
1002022
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
X Wang, S Liu, Y Sun, X Yu, SM Lee, Q Cheng, T Wei, J Gong, ...
Nature protocols 18 (1), 265-291, 2023
952023
A biomimetic total synthesis of (+)-ainsliadimer A
C Li, X Yu, X Lei
Organic letters 12 (19), 4284-4287, 2010
862010
Zwitterionic phospholipidation of cationic polymers facilitates systemic mRNA delivery to spleen and lymph nodes
S Liu, X Wang, X Yu, Q Cheng, LT Johnson, S Chatterjee, D Zhang, ...
Journal of the American Chemical Society 143 (50), 21321-21330, 2021
752021
A systematic study of unsaturation in lipid nanoparticles leads to improved mRNA transfection in vivo
SM Lee, Q Cheng, X Yu, S Liu, LT Johnson, DJ Siegwart
Angewandte Chemie 133 (11), 5912-5917, 2021
682021
Stereoselective 6π-electron electrocyclic ring closures of 2-halo-amidotrienes via a remote 1, 6-asymmetric induction
R Hayashi, MC Walton, RP Hsung, JH Schwab, X Yu
Organic letters 12 (24), 5768-5771, 2010
452010
TfOH-mediated [2 + 2 + 2] cycloadditions of ynamides with two discrete nitriles: synthesis of 4-aminopyrimidine derivatives
YT Ping Chen, Cai-xia Song, Wan-shu Wang, Xue-liang Yu
RSC Adv. 6 (RSC), 80055-80058, 2016
392016
Lipid‐Modified Aminoglycosides for mRNA Delivery to the Liver
X Yu, S Liu, Q Cheng, T Wei, S Lee, D Zhang, DJ Siegwart
Advanced Healthcare Materials, 1901487, 2020
282020
In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
Y Jia, L Li, YH Lin, P Gopal, S Shen, K Zhou, X Yu, T Sharma, Y Zhang, ...
Cell Stem Cell 29 (3), 372-385. e8, 2022
212022
Hydrophobic domain structure of linear-dendritic poly (ethylene glycol) lipids affects RNA delivery of lipid nanoparticles
K Zhou, LT Johnson, H Xiong, S Barrios, JT Minnig, Y Yan, B Abram, X Yu, ...
Molecular Pharmaceutics 17 (5), 1575-1585, 2020
182020
ASSEMBLY OF THE SOUTHERN MACROCYCLIC HALF OF (+)-SPIRASTRELLOLIDE A THROUGH CYCLIC ACETAL TETHERED RING-CLOSING METATHESIS AND 1, 3-ANTI-MUKAIYAMA-ALDOL (Dedicated to Professor …
RP Tang, Y, Yang, JH, Liu, J, Wang, CC, Lv, MC, Wu, YB, Yu, XL, Ko, CH, Hsung
Heterocycles: an international journal for reviews and communications in …, 2012
102012
Hydrophobic optimization of functional poly (TPAE-co-suberoyl chloride) for extrahepatic mRNA delivery following Intravenous Administration
X Yu, S Liu, Q Cheng, SM Lee, T Wei, D Zhang, L Farbiak, LT Johnson, ...
Pharmaceutics 13 (11), 1914, 2021
82021
A convergent approach toward fidaxomicin: Syntheses of the fully glycosylated northern and southern fragments
R Hollibaugh, X Yu, JK De Brabander
Tetrahedron 76 (49), 131673, 2020
62020
Functional Rescue of CFTR by Aerosolized Delivery of Optimized CFTR mRNA Using ReCode LNPs in Primary Human Bronchial Epithelial Cells Derived from Patients with Cystic Fibrosis
D Ishimaru, D Boudko, EA Meleshkevitch, MS Sidhu, JR Poniatowski, ...
D109. AIRWAY OF INTEREST: EPITHELIAL AND SMOOTH MUSCLE FUNCTION IN HEALTH …, 2022
32022
An mRNA-Based Therapy to Treat Primary Ciliary Dyskinesia: Aerosol Delivery, Biodistribution and Tolerability
D Liston, M Hennig, D Ishimaru, JK Eby, S Ahmed, X Yu, A Alfaifi, ...
A62 Cystic fibrosis and NON-CF bronchiectasis: mechanistic insights …, 2022
32022
583: Variant-agnostic CFTR rescue using aerosolized delivery of CFTR mRNA using the SORT-LNP in primary human bronchial epithelial cells derived from patients with cystic fibrosis
M Torres, D Boudko, E Meleshkevitch, M Coquelin, X Yu, J Eby, ...
Journal of Cystic Fibrosis 20, S278, 2021
22021
WS09. 3 Rescue of CFTR function in primary bronchial epithelial cells from patients with cystic fibrosis using lipid nanoparticle delivery of RNAbased therapies
M Torres, D Boudko, E Meleshkevitch, M Coquelin, X Yu, J Eby, ...
Journal of Cystic Fibrosis 20, S17-S18, 2021
22021
Rescue of Ciliary Function in Cell-Based Primary Ciliary Dyskinesia Models Using Nebulized, Lipid Nanoparticle (LNP)-Formulated mRNA
R Bhattacharjee, M Hennig, D Ishimaru, DR Liston, JK Eby, CC Corona, ...
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS, A1998 …, 2022
12022
Total Synthesis of Mangrolide A
X Yu
12018
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