Kieran Smallbone

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Pedro MendesUniversity of ConnecticutVerified email at uchc.edu
Douglas KellUniversity of LiverpoolVerified email at liv.ac.uk
Vangelis SimeonidisSenior Project Manager, PATHVerified email at path.org
Philip MainiProfessor of Mathematical BiologyVerified email at maths.ox.ac.uk
Neil SwainstonEpoch BiodesignVerified email at epochbiodesign.com
Ettore MurabitoResearch Associate, University of ManchesterVerified email at manchester.ac.uk
Warwick DunnDepartment of Biochemistry and Systems Biology, ISMIB, University of LiverpoolVerified email at liverpool.ac.uk
David GavaghanProfessor of Computational Biology, University of OxfordVerified email at cs.ox.ac.uk
Norman W. PatonProfessor of Computer Science, University of ManchesterVerified email at manchester.ac.uk
S.G. OliverUniversity of CambridgeVerified email at cam.ac.uk
Natalie J StanfordConsultant, Hybrid IntelligenceVerified email at tessella.com
David BroomheadProfessor of Applied Mathematics, University of ManchesterVerified email at Manchester.ac.uk
Hans WesterhoffUniversity of Amsterdam, VU University Amsterdam, University of ManchesterVerified email at manchester.ac.uk
Catherine L WinderDepartment of Biochemistry and Systems Biology, ISMIB, University of LiverpoolVerified email at Liverpool.ac.uk
Paul DobsonScruffy Biotech LtdVerified email at manchester.ac.uk
Robert GilliesChair of Cancer Physiology, H. Lee Moffitt Cancer CenterVerified email at moffitt.org
Pinar PirDepartment of Bioengineering, Gebze Technical University, TurkeyVerified email at gtu.edu.tr
Daniel JamesonUniversity of ManchesterVerified email at manchester.ac.uk
Joseph Olufemi DadaProfessor of Electrical Engineering, Afe Babalola University, Ado-EkitiVerified email at abuad.edu.ng
Benjamin D. HeavnerResearch Scientist, University of WashingtonVerified email at uw.edu

Kieran Smallbone

MCISB / Mathematics / Computer Science, University of Manchester

Verified email at manchester.ac.uk - Homepage

metabolism systems biology mathematical biology


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A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013	1203	2013
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ... Nature biotechnology 26 (10), 1155-1160, 2008	692	2008
An assessment of sustainable housing affordability using a multiple criteria decision making method E Mulliner, K Smallbone, V Maliene Omega 41 (2), 270-279, 2013	474	2013
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer RA Gatenby, K Smallbone, PK Maini, F Rose, J Averill, RB Nagle, ... British journal of cancer 97 (5), 646-653, 2007	448	2007
Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016	325	2016
Metabolic changes during carcinogenesis: potential impact on invasiveness K Smallbone, RA Gatenby, RJ Gillies, PK Maini, DJ Gavaghan Journal of theoretical biology 244 (4), 703-713, 2007	249	2007
SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020	228	2020
The role of acidity in solid tumour growth and invasion K Smallbone, DJ Gavaghan, RA Gatenby, PK Maini Journal of theoretical biology 235 (4), 476-484, 2005	202	2005
Towards a genome-scale kinetic model of cellular metabolism K Smallbone, E Simeonidis, N Swainston, P Mendes BMC systems biology 4 (1), 6, 2010	199	2010
Improving metabolic flux predictions using absolute gene expression data K Smallbone, D Lee, WB Dunn, E Murabito, CL Winder, DB Kell, ... BMC Systems Biology 6, 73, 2012	185*	2012
Yeast 5 – an expanded reconstruction of the Saccharomyces cerevisiae metabolic network BD Heavner, K Smallbone, B Barker, P Mendes, LP Walker BMC Systems Biology 6, 55, 2012	183	2012
A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes K Smallbone, HL Messiha, KM Carroll, CL Winder, N Malys, WB Dunn, ... FEBS letters 587 (17), 2832-2841, 2013	160	2013
Systematic construction of kinetic models from genome-scale metabolic networks NJ Stanford, T Lubitz, K Smallbone, E Klipp, P Mendes, W Liebermeister PloS one 8 (11), e79195, 2013	147	2013
Further developments towards a genome-scale metabolic model of yeast K Smallbone, P Dobson, D Jameson, E Simeonidis, K Lanthaler, P Pir, ... BMC Systems Biology 4, 145, 2010	144*	2010
The SuBliMinaL toolbox: automating steps in the reconstruction of metabolic networks N Swainston, K Smallbone, P Mendes, D Kell, N Paton Journal of Integrative Bioinformatics 8 (2), 186, 2011	128	2011
Something from nothing − bridging the gap between constraint‐based and kinetic modelling K Smallbone, E Simeonidis, DS Broomhead, DB Kell FEBS Journal 274 (21), 5576-5585, 2007	127	2007
Metabolic regulation is sufficient for global and robust coordination of glucose uptake, catabolism, energy production and growth in Escherichia coli P Millard, K Smallbone, P Mendes PLoS computational biology 13 (2), e1005396, 2017	124	2017
Version 6 of the consensus yeast metabolic network refines biochemical coverage and improves model performance BD Heavner, K Smallbone, ND Price, LP Walker Database 2013, bat059, 2013	124	2013
Flux balance analysis: A geometric perspective K Smallbone, E Simeonidis Journal of theoretical biology 258 (2), 311-315, 2009	99	2009
BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology AF Villaverde, D Henriques, K Smallbone, S Bongard, J Schmid, ... BMC systems biology 9, 1-15, 2015	96	2015

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