| Online chemical modeling environment (OCHEM): web platform for data storage, model development and publishing of chemical information I Sushko, S Novotarskyi, R Körner, AK Pandey, M Rupp, W Teetz, ... Journal of computer-aided molecular design 25, 533-554, 2011 | 517 | 2011 |
| Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites S Ekins, C Chang, S Mani, MD Krasowski, EJ Reschly, M Iyer, ... Molecular pharmacology 72 (3), 592-603, 2007 | 165 | 2007 |
| Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). MM Tabb, V Kholodovych, F Grün, C Zhou, WJ Welsh, B Blumberg Environmental health perspectives 112 (2), 163-169, 2004 | 152 | 2004 |
| Self-assembled cationic amphiphiles as antimicrobial peptides mimics: role of hydrophobicity, linkage type, and assembly state Y Zhang, A Algburi, N Wang, V Kholodovych, DO Oh, M Chikindas, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 343-352, 2017 | 124 | 2017 |
| Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo DR Lewis, LK Petersen, AW York, KR Zablocki, LB Joseph, ... Proceedings of the National Academy of Sciences 112 (9), 2693-2698, 2015 | 104 | 2015 |
| Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation PV Paranjpe, Y Chen, V Kholodovych, W Welsh, S Stein, PJ Sinko Journal of controlled release 100 (2), 275-292, 2004 | 102 | 2004 |
| Neural network studies. 3. Variable selection in the cascade-correlation learning architecture VV Kovalishyn, IV Tetko, AI Luik, VV Kholodovych, AEP Villa, ... Journal of Chemical Information and Computer Sciences 38 (4), 651-659, 1998 | 102 | 1998 |
| Shape signatures: new descriptors for predicting cardiotoxicity in silico DS Chekmarev, V Kholodovych, KV Balakin, Y Ivanenkov, S Ekins, ... Chemical research in toxicology 21 (6), 1304-1314, 2008 | 87 | 2008 |
| Computational discovery of novel low micromolar human pregnane X receptor antagonists S Ekins, V Kholodovych, N Ai, M Sinz, J Gal, L Gera, WJ Welsh, ... Molecular pharmacology 74 (3), 662-672, 2008 | 86 | 2008 |
| Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius JA Rosenfeld, D Reeves, MR Brugler, A Narechania, S Simon, R Durrett, ... Nature communications 7 (1), 10164, 2016 | 80 | 2016 |
| Accurate predictions of cellular response using QSPR: a feasibility test of rational design of polymeric biomaterials V Kholodovych, JR Smith, D Knight, S Abramson, J Kohn, WJ Welsh Polymer 45 (22), 7367-7379, 2004 | 70 | 2004 |
| Design, Synthesis, Evaluation, and Structural Studies of C2-Symmetric Small Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 … S Basu, J Yang, B Xu, K Magiera-Mularz, L Skalniak, B Musielak, ... Journal of medicinal chemistry 62 (15), 7250-7263, 2019 | 65 | 2019 |
| Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA (s) OB Garbuzenko, V Ivanova, V Kholodovych, DC Reimer, KR Reuhl, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (6), 1983-1992, 2017 | 60 | 2017 |
| Requirement of gamma-carboxyglutamic acid modification and phosphatidylserine binding for the activation of Tyro3, Axl, and Mertk receptors by growth arrest-specific 6 K Geng, S Kumar, SG Kimani, V Kholodovych, C Kasikara, K Mizuno, ... Frontiers in immunology 8, 1521, 2017 | 54 | 2017 |
| 3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies Y Peng, SM Keenan, Q Zhang, V Kholodovych, WJ Welsh Journal of medicinal chemistry 48 (5), 1620-1629, 2005 | 49 | 2005 |
| Using surrogate modeling in the prediction of fibrinogen adsorption onto polymer surfaces JR Smith, D Knight, J Kohn, K Rasheed, N Weber, V Kholodovych, ... Journal of chemical information and computer sciences 44 (3), 1088-1097, 2004 | 49 | 2004 |
| Predicting fibrinogen adsorption to polymeric surfaces in silico: a combined method approach JR Smith, V Kholodovych, D Knight, J Kohn, WJ Welsh Polymer 46 (12), 4296-4306, 2005 | 45 | 2005 |
| Prediction of fibrinogen adsorption for biodegradable polymers: Integration of molecular dynamics and surrogate modeling AV Gubskaya, V Kholodovych, D Knight, J Kohn, WJ Welsh Polymer 48 (19), 5788-5801, 2007 | 41 | 2007 |
| The major human pregnane X receptor (PXR) splice variant, PXR. 2, exhibits significantly diminished ligand-activated transcriptional regulation YS Lin, K Yasuda, M Assem, C Cline, J Barber, CW Li, V Kholodovych, ... Drug metabolism and disposition 37 (6), 1295-1304, 2009 | 39 | 2009 |
| Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity SG Kimani, S Kumar, N Bansal, K Singh, V Kholodovych, T Comollo, ... Scientific reports 7 (1), 1-11, 2017 | 37 | 2017 |
