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Consuelo Torrini
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Year
Common regulatory pathways mediate activity of microRNAs inducing cardiomyocyte proliferation
C Torrini, RJ Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, MI Gutierrez, ...
Cell reports 27 (9), 2759-2771. e5, 2019
612019
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
SMD Nguyen T, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela ...
J Clin Invest, 2020
492020
MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in GlioblastomaAcute and Chronic MET Inhibition Drives Oxidative Metabolism
Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ...
Cancer research 80 (1), 30-43, 2020
222020
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition.
SMD Nguyen TTT, Ishida CT, Shang E, Shu C, Torrini C, Zhang Y, Bianchetti E ...
EMBO Mol Med, 2019
202019
Notch pathway activation enhances cardiosphere in vitro expansion
I Secco, L Barile, C Torrini, L Zentilin, G Vassalli, M Giacca, C Collesi
Journal of cellular and molecular medicine 22 (11), 5583-5595, 2018
72018
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
A Raso, E Dirkx, V Sampaio-Pinto, H El Azzouzi, RJ Cubero, ...
Nature communications 12 (1), 1-14, 2021
62021
Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma
C Torrini, TTT Nguyen, C Shu, A Mela, N Humala, A Mahajan, EH Seeley, ...
Molecular Cell, 2022
2022
Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in GlioblastomaHDACi and Imipridones Enhance Cell Death in Glioblastoma
TTT Nguyen, E Shang, S Schiffgens, C Torrini, C Shu, HO Akman, ...
Clinical Cancer Research, OF1-OF15, 2022
2022
INDUCTION OF SYNTHETIC LETHALITY BY ACTIVATION OF MITOCHONDRIAL CLPP AND INHIBITION OF HDAC1/2 IN GLIOBLASTOMA
T Nguyen, E Shang, S Schiffgens, C Torrini, E Bianchetti, C Shu, ...
NEURO-ONCOLOGY 23, 201-201, 2021
2021
ETMM-05. LACTIC ACID FACILITATES GLIOBLASTOMA GROWTH THROUGH MODULATION OF THE EPIGENOME
C Torrini, T Nguyen, C Shu, A Mela, N Humala, A Mahajan, ...
Neuro-oncology Advances 3 (Suppl 1), i15, 2021
2021
A microRNA program controls the transition of cardiomyocyte hyperplasia to hypertrophy and stimulates mammalian cardiac regeneration
A Raso, E Dirkx, V Sampaio-Pinto, H el Azzouzi, RJ Cubero, ...
bioRxiv, 2021
2021
EXTH-50. ACTIVATION OF THE MITOCHONDRIAL CLPP PROTEASE IS SYNTHETICALLY LETHAL WITH HDAC1/2 INHIBITION IN GLIOBLASTOMA MODEL SYSTEMS
S Schiffgens, T Nguyen, C Shu, B Elena, C Torrini, G Karpel-Massler, ...
Neuro-Oncology 22 (Suppl 2), ii98, 2020
2020
EPCO-16. LACTIC ACID IS AN EPIGENETIC METABOLITE THAT DRIVES GLIOBLASTOMA SURVIVAL AND GROWTH
C Torrini, T Nguyen, C Shu, A Mela, N Humala, A Mahajan, ...
Neuro-Oncology 22 (Suppl 2), ii72, 2020
2020
CBMT-15. MET INHIBITION DRIVES PGC1A DEPENDENT METABOLIC REPROGRAMMING AND ELICITS UNIQUE METABOLIC VULNERABILITIES IN GLIOBLASTOMA
Y Zhang, T Nguyen, J Zhao, E Shang, C Torrini, PD Canoll, ...
Neuro-Oncology 21 (Suppl 6), vi36, 2019
2019
232 Administration of miR-665 modulates cardiomiocyte mechanotransduction and prevents pathological cardiac remodelling after pressure overload
L Braga, M Dal Ferro, M Mano, A Eulalio, H Ali, A Cannata, C Torrini, ...
Cardiovascular Research 114 (suppl_1), S60-S60, 2018
2018
Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules
C Torrini
PQDT-UK & Ireland, 2018
2018
Pro-proliferative microRNAs inducing cardiac regeneration target genes involved in Hippo-Yap signaling and actin cytoskeleton remodeling
C Torrini, MI Gutierrez, L Zentilin, L Braga, S Zacchigna, E Dirkx, M Giacca
HUMAN GENE THERAPY 27 (11), A100-A100, 2016
2016
A central role for Hippo pathway and actin filament dynamics in microRNA-induced cardiomyocyte proliferation
C Torrini, MI Gutierrez, L Zentilin, L Braga, M Mano, S Zacchigna, E Dirkx, ...
EUROPEAN JOURNAL OF HEART FAILURE 18, 432-433, 2016
2016
King’s Research Portal
C Torrini, R Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, M Giacca
CELL-REPORTS 500, 17-02259R3, 0
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