| HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models. SMD Nguyen T, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela ... J Clin Invest, 2020 | 115 | 2020 |
| Common regulatory pathways mediate activity of microRNAs inducing cardiomyocyte proliferation C Torrini, RJ Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, MI Gutierrez, ... Cell reports 27 (9), 2759-2771. e5, 2019 | 88 | 2019 |
| MET inhibition elicits PGC1α-dependent metabolic reprogramming in glioblastoma Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ... Cancer research 80 (1), 30-43, 2020 | 37 | 2020 |
| Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition. SMD Nguyen TTT, Ishida CT, Shang E, Shu C, Torrini C, Zhang Y, Bianchetti E ... EMBO Mol Med, 2019 | 36 | 2019 |
| Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma C Torrini, TTT Nguyen, C Shu, A Mela, N Humala, A Mahajan, EH Seeley, ... Molecular cell 82 (16), 3061-3076. e6, 2022 | 31 | 2022 |
| Induction of synthetic lethality by activation of mitochondrial ClpP and inhibition of HDAC1/2 in glioblastoma TTT Nguyen, E Shang, S Schiffgens, C Torrini, C Shu, HO Akman, ... Clinical Cancer Research 28 (9), 1881-1895, 2022 | 19 | 2022 |
| A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration A Raso, E Dirkx, V Sampaio-Pinto, H El Azzouzi, RJ Cubero, ... Nature communications 12 (1), 4808, 2021 | 16 | 2021 |
| Notch pathway activation enhances cardiosphere in vitro expansion I Secco, L Barile, C Torrini, L Zentilin, G Vassalli, M Giacca, C Collesi Journal of cellular and molecular medicine 22 (11), 5583-5595, 2018 | 7 | 2018 |
| CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis N Nayyar, MA de Sauvage, J Chuprin, EM Sullivan, M Singh, C Torrini, ... Clinical Cancer Research 30 (2), 420-435, 2024 | 3 | 2024 |
| DDDR-05. ERK INHIBITION INCREASES SENSITIVITY TO ANTI-PD-1 THERAPY IN A MOUSE MODEL OF BRAF MUTANT MELANOMA BRAIN METASTASIS PB Magali de Sauvage, Naema Nayyar, Consuelo Torrini, Edwin Nieblas-Bedolla Neuro-Oncology 24 (Issue Supplement_7), Page vii99, 2022 | 1 | 2022 |
| Author Correction: A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration A Raso, E Dirkx, V Sampaio-Pinto, H El Azzouzi, RJ Cubero, ... nature communications 13, 2022 | 1 | 2022 |
| OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma TTT Nguyen, C Torrini, E Shang, C Shu, JY Mun, Q Gao, N Humala, ... JCI insight, 2024 | | 2024 |
| The ERK inhibitor LY3214996 augments anti-PD-1 immunotherapy in preclinical mouse models of BRAFV600E melanoma brain metastasis MA de Sauvage, C Torrini, E Nieblas-Bedolla, EJ Summers, E Sullivan, ... Neuro-oncology, noad248, 2023 | | 2023 |
| EXTH-42. PRECLINICAL INVESTIGATION OF A NOVEL BRAIN PENETRANT MEK INHIBITOR TO TARGET BRAIN METASTASIS E Yamazawa, N Nayyar, N Ijad, C Torrini, M De Sauvage, C Migliarese, ... Neuro-Oncology 25 (Supplement_5), v233-v234, 2023 | | 2023 |
| EXTH-45. DEVELOPMENT OF COMBINATION THERAPIES OF KRASG12C INHIBITOR ADAGRASIB IN PRECLINICAL MODELS OF BRAIN METASTASIS C Torrini, C Migliarese, E Summers, FT Demir, N Ijad, N Nayyar, ... Neuro-Oncology 25 (Supplement_5), v234-v234, 2023 | | 2023 |
| Dyrk1a kinase controls cardiomyocyte proliferation G Rizzari, E Dirkx, C Torrini, M Tomczyk, M Mano, M Giacca Journal of Molecular and Cellular Cardiology 173, S109, 2022 | | 2022 |
| TMET-39. INHIBITION OF THE TCA-CYCLE IS SYNTHETICALLY LETHAL WITH LOSS OF FUNCTION OF BCL-XL IN GLIOBLASTOMA MS Trang Nguyen, Enyuan Shang, Consuelo Torrini, Chang Shu, Mike-Andrew ... Neuro-Oncology 24 (Issue Supplement_7), vii270, 2022 | | 2022 |
| A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration (vol 12, 4808, 2021) A Raso, E Dirkx, V Sampaio-Pinto, H el Azzouzi, RJ Cubero, ... NATURE COMMUNICATIONS 13 (1), 2022 | | 2022 |
| Abstract P1002: Elucidating The Role Of Dyrk1a Kinase In Controlling Cardiomyocyte Proliferation G Rizzari, E Dirkx, C Torrini, M Tomczyk, M Mano, M Giacca Circulation Research 131 (Suppl_1), AP1002-AP1002, 2022 | | 2022 |
| INDUCTION OF SYNTHETIC LETHALITY BY ACTIVATION OF MITOCHONDRIAL CLPP AND INHIBITION OF HDAC1/2 IN GLIOBLASTOMA T Nguyen, E Shang, S Schiffgens, C Torrini, E Bianchetti, C Shu, ... NEURO-ONCOLOGY 23, 201-201, 2021 | | 2021 |
