Devarajan Karunagaran

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Dr. Ruby John AntoScientist G, Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology( Super-annuated))Verified email at rgcb.res.in
Eldad TzahorWeizmann Institute of ScienceVerified email at weizmann.ac.il
Gil LevkowitzWeizmann Institute of ScienceVerified email at weizmann.ac.il
Sakthivel RamasamySenior Research Associate, Dept.of Biotechnology, IIT MadrasVerified email at imail.iitm.ac.in
Nagini siddavaramRetired Professor, Annamalai University. Regional Director, World Neem OrganisationVerified email at annamalaiuniversity.ac.in
Karthik Subramanian ChandrasekaranPost Doctoral Research Associate, University of Bristol, BristolVerified email at bristol.ac.uk
anusha sathyanarayananPost doctoral fellow, Max Planck instituteVerified email at mpi-muenster.mpg.de
Priyanshu SharmaPostdoctoral Research Fellow, Massachusetts General Hospital, Harvard Medical SchoolVerified email at mgh.harvard.edu
Tessy Thomas MaliekalScientist EII, RGCBVerified email at rgcb.res.in
Venkatraman ManickamAssociate Professor, VIT UniversityVerified email at vit.ac.in
Mien-Chie HungChina Medical University, TaiwanVerified email at cmu.edu.tw
GK SuraishkumarProfessor, Department of Biotechnology, IIT MadrasVerified email at iitm.ac.in
Sandhya - SundaramProfessor and Head , Pathology and Senior Consultant, Sri Ramachandra Medical College and ResearchVerified email at sriramachandra.edu.in
Srinivas GopalaScientist G & Head, Department of Biochemistry, Sree Chitra Tirunal Institute for Medical SciencesVerified email at sctimst.ac.in
Smitha V BavaAsst Professor, University of CalicutVerified email at uoc.ac.in
Dinesh RaghuLa Trobe UniversityVerified email at onjcri.org.au
Rony SegerWeizmann Institute of ScienceVerified email at weizmann.ac.il
Sripriya ParanthamanAssistant Professor, Department of Plant Biology and Plant Biotechnology, Presidency CollegeVerified email at presidencycollegechennai.ac.in
Elior PelesWeizmann Institute of ScienceVerified email at weizmann.ac.il
Amal Kanti BeraDepartment of Biotechnology, IIT MadrasVerified email at iitm.ac.in

Devarajan Karunagaran

Emeritus Professor, Bhupat and Jyoti Mehta School of Biosciences, Department of Biotechnology

Verified email at iitm.ac.in - Homepage

cancer biology apoptosis signal transduction miRNAs in cancer


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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. E Tzahar, H Waterman, X Chen, G Levkowitz, D Karunagaran, S Lavi, ... Molecular and Cellular Biology 16, 5276-5287, 1996	1434	1996
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. D Karunagaran, E Tzahar, RR Beerli, X Chen, D Graus-Porta, BJ Ratzkin, ... The EMBO journal 15, 254-264, 1996	950	1996
The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition R Vidya Priyadarsini, R Senthil Murugan, S Maitreyi, K Ramalingam, ... European journal of pharmacology 649, 84-91, 2010	466	2010
Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells S Oommen, RJ Anto, G Srinivas, D Karunagaran European journal of pharmacology 485 (1-3), 97-103, 2004	382	2004
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms. E Tzahar, G Levkowitz, D Karunagaran, L Yi, E Peles, S Lavi, D Chang, ... Journal of Biological Chemistry 269, 25226-25233, 1994	378	1994
Induction of apoptosis by curcumin and its implications for cancer therapy D Karunagaran, R Rashmi, TR Kumar Curr Cancer Drug Targets 5, 117-129, 2005	349	2005
Structural and functional aspects of the multiplicity of Neu differentiation factors. D Wen, SV Suggs, D Karunagaran, N Liu, RL Cupples, Y Luo, ... Molecular and cellular biology 14, 1909-1919, 1994	315	1994
Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization VB Smitha, TP Vinesh Kumar, A Deepti, A Nair, D Karunagaran, RJ Anto Journal of Biological Chemistry 280, 6301-6308, 2005	277	2005
Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9 G Srinivas, RJ Anto, P Srinivas, S Vidhyalakshmi, VP Senan, ... European journal of pharmacology 473, 117-125, 2003	255	2003
Advances in chalcones with anticancer activities C Karthikeyan, N SH Narayana Moorthy, S Ramasamy, U Vanam, ... Recent patents on anti-cancer drug discovery 10 (1), 97-115, 2015	241	2015
NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix A Nair, M Venkatraman, TT Maliekal, B Nair, D Karunagaran Oncogene 22, 50-58, 2003	239	2003
An immunological approach reveals biological differences between the two NDF/heregulin receptors, ErbB-3 and ErbB-4 X Chen, G Levkowitz, E Tzahar, D Karunagaran, S Lavi, N Ben-Baruch, ... Journal of Biological Chemistry 271, 7620-7629, 1996	183	1996
Inhibition of nuclear factor-κB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis R Shao, D Karunagaran, BP Zhou, K Li, SS Lo, J Deng, P Chiao, ... Journal of Biological Chemistry 272, 32739-32742, 1997	166	1997
The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells RV Priyadarsini, RS Murugan, P Sripriya, D Karunagaran, S Nagini Free radical research 44, 624-634, 2010	159	2010
Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases R Rashmi, TR Santhosh Kumar, D Karunagaran FEBS letters 538, 19-24, 2003	147	2003
Chlorophyll Revisited: Anti-inflammatory Activities of Chlorophyll a and Inhibition of Expression of TNF-α Gene by the Same A Subramoniam, VV Asha, SA Nair, SP Sasidharan, PK Sureshkumar, ... Inflammation 35, 959-966, 2012	138	2012
Biological and chemical inhibitors of NF‐κB sensitize SiHa cells to cisplatin‐induced apoptosis M Venkatraman, RJ Anto, A Nair, M Varghese, D Karunagaran Molecular carcinogenesis 44, 51-59, 2005	133	2005
Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL R Rashmi, S Kumar, D Karunagaran Carcinogenesis 26, 713-723, 2005	126	2005
Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells PC Thacker, D Karunagaran PloS one 10 (3), e0120045, 2015	113	2015
Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis R Rashmi, S Kumar, D Karunagaran Carcinogenesis 25, 179-187, 2004	112	2004

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