Jia Yu

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David M. VirshupDuke-NUS Medical School SingaporeVerified email at duke-nus.edu.sg
Tracy M. CoveyProfessor of Chemistry, Weber State UniversityVerified email at weber.edu
Gary CoombsProfessor of Biology, Waldorf UniversityVerified email at waldorf.edu
Ivana MihalekUniversity of RijekaVerified email at uniri.hr
Jit Kong CheongResearch Assistant Professor, Yong Loo Lin School of Medicine, NUSVerified email at nus.edu.sg
Babita MadanAssistant Professor at Duke-NUS Medical SchoolVerified email at duke-nus.edu.sg
Simran KaurMcGill Goodman Cancer Research CenterVerified email at mail.mcgill.ca
Marian L. WatermanProfessor, Department of Microbiology and Molecular GeneticsVerified email at uci.edu
Frederic BardSenior Principal Investigator, IMCBVerified email at imcb.a-star.edu.sg
Zheng ZhongDuke-NUS Medical School SingaporeVerified email at duke-nus.edu.sg
Rie NygaardPost Doc, Columbia UniversityVerified email at cumc.columbia.edu
Oliver B ClarkeColumbia UniversityVerified email at columbia.edu
Nathan HarmstonYale-NUS / Duke-NUSVerified email at yale-nus.edu.sg
Franck PerezInstitut Curie / CNRSVerified email at curie.fr

Jia Yu

Senior Research Fellow, Duke-NUS Medical School

Verified email at duke-nus.edu.sg

Wnt Signaling and Regulation Protein Trafficking


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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification GS Coombs, J Yu, CA Canning, CA Veltri, TM Covey, JK Cheong, ... Journal of Cell Science 123, 3357-3367, 2010	202	2010
A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities R Najdi, K Proffitt, S Sprowl, S Kaur, J Yu, TM Covey, DM Virshup, ... Differentiation 84 (2), 203-213, 2012	165	2012
WLS Retrograde Transport to the Endoplasmic Reticulum during Wnt Secretion J Yu, J Chia, CA Canning, CM Jones, FA Bard, D Virshup Developmental Cell 29 (3), 277-291, 2014	139	2014
Updating the Wnt pathways J Yu, DM Virshup Bioscience Reports 34 (5), 593, 2014	91	2014
Wnts and the hallmarks of cancer Z Zhong, J Yu, DM Virshup, B Madan Cancer and Metastasis Reviews 39 (3), 625-645, 2020	52	2020
Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion R Nygaard, J Yu, J Kim, DR Ross, G Parisi, OB Clarke, DM Virshup, ... Cell 184 (1), 194-206. e14, 2021	40	2021
Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression J Stewart, J James, GW McCluggage, S McQuaid, K Arthur, D Boyle, ... Modern Pathology 28 (3), 2015	34	2015
The functional landscape of patient-derived RNF43 mutations predicts sensitivity to Wnt inhibition J Yu, PAM Yusoff, DTJ Woutersen, P Goh, N Harmston, R Smits, ... Cancer Research 80 (24), 5619-5632, 2020	23	2020
Wnt traffic from endoplasmic reticulum to filopodia N Moti, J Yu, G Boncompain, F Perez, DM Virshup PloS one 14 (2), e0212711, 2019	22	2019
A human pleiotropic multiorgan condition caused by deficient Wnt secretion G Chai, E Szenker-Ravi, C Chung, Z Li, L Wang, M Khatoo, T Marshall, ... New England Journal of Medicine 385 (14), 1292-1301, 2021	17	2021

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