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Norberto Gonzalez-Juarbe
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Pore-forming toxins induce macrophage necroptosis during acute bacterial pneumonia
N González-Juarbe, RP Gilley, CA Hinojosa, KM Bradley, A Kamei, G Gao, ...
PLoS pathogens 11 (12), e1005337, 2015
2292015
NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis
D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun, CJ Orihuela, M Niederweis
Cell reports 24 (2), 429-440, 2018
1582018
Severe pneumococcal pneumonia causes acute cardiac toxicity and subsequent cardiac remodeling
LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, A Anzueto, BL Babu, ...
American Journal of Respiratory and Critical Care Medicine 196 (5), 609-620, 2017
1252017
Streptococcus pneumoniae biofilm formation is strain dependent, multifactorial, and associated with reduced invasiveness and immunoreactivity during colonization
K Blanchette-Cain, CA Hinojosa, R Akula Suresh Babu, A Lizcano, ...
MBio 4 (5), 10.1128/mbio. 00745-13, 2013
1152013
Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia
N González-Juarbe, KM Bradley, AT Shenoy, RP Gilley, LF Reyes, ...
Cell Death & Differentiation 24 (5), 917-928, 2017
982017
Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing
AT Shenoy, T Brissac, RP Gilley, N Kumar, Y Wang, N Gonzalez-Juarbe, ...
PLoS pathogens 13 (8), e1006582, 2017
662017
Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion
RP Gilley, N González-Juarbe, AT Shenoy, LF Reyes, PH Dube, ...
Infection and immunity 84 (5), 1457-1469, 2016
662016
Killing of Serratia marcescens biofilms with chloramphenicol
C Ray, AT Shenoy, CJ Orihuela, N González-Juarbe
Annals of clinical microbiology and antimicrobials 16, 1-6, 2017
512017
A non-human primate model of severe pneumococcal pneumonia
LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, AT Shenoy, RP Gilley, ...
PloS one 11 (11), e0166092, 2016
422016
Bacterial pore-forming toxins promote the activation of caspases in parallel to necroptosis to enhance alarmin release and inflammation during pneumonia
N Gonzalez-Juarbe, KM Bradley, AN Riegler, LF Reyes, T Brissac, ...
Scientific reports 8 (1), 5846, 2018
412018
Necroptotic cell death promotes adaptive immunity against colonizing pneumococci
AN Riegler, T Brissac, N Gonzalez-Juarbe, CJ Orihuela
Frontiers in Immunology 10, 443117, 2019
402019
Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumonia
N González-Juarbe, CA Mares, CA Hinojosa, JL Medina, A Cantwell, ...
Infection and immunity 83 (2), 614-624, 2015
402015
Influenza-induced oxidative stress sensitizes lung cells to bacterial-toxin-mediated necroptosis
N Gonzalez-Juarbe, AN Riegler, AS Jureka, RP Gilley, JD Brand, ...
Cell reports 32 (8), 2020
342020
NAD hydrolysis by the tuberculosis necrotizing toxin induces lethal oxidative stress in macrophages
D Pajuelo, N Gonzalez‐Juarbe, M Niederweis
Cellular microbiology 22 (1), e13115, 2020
282020
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza
SS Park, N Gonzalez-Juarbe, AN Riegler, H Im, Y Hale, MP Platt, ...
Cell reports 35 (11), 2021
252021
Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia
CA Hinojosa, N Gonzalez-Juarbe, MM Rahman, G Fernandes, ...
Microbial pathogenesis 141, 103979, 2020
222020
Kinetic multi-omic analysis of responses to SARS-CoV-2 infection in a model of severe COVID-19
AM Cantwell, H Singh, M Platt, Y Yu, YH Lin, Y Ikeno, G Hubbard, Y Xiang, ...
Journal of virology 95 (20), 10.1128/jvi. 01010-21, 2021
202021
Global proteome and phosphoproteome characterization of sepsis-induced kidney injury
YH Lin, MP Platt, H Fu, Y Gui, Y Wang, N Gonzalez-Juarbe, D Zhou, Y Yu
Molecular & Cellular Proteomics 19 (12), 2030-2047, 2020
202020
Streptococcus pneumoniae binds to host lactate dehydrogenase via PspA and PspC to enhance virulence
SS Park, N Gonzalez-Juarbe, E Martínez, JY Hale, YH Lin, JT Huffines, ...
MBio 12 (3), 10.1128/mbio. 00673-21, 2021
192021
Inhibition of necroptosis to prevent long-term cardiac damage during pneumococcal pneumonia and invasive disease
SM Beno, AN Riegler, RP Gilley, T Brissac, Y Wang, KL Kruckow, ...
The Journal of infectious diseases 222 (11), 1882-1893, 2020
172020
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