| Inhibition of the NF-κB signaling pathway by the curcumin analog, 3, 5-Bis (2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties A Olivera, TW Moore, F Hu, AP Brown, A Sun, DC Liotta, JP Snyder, ... International immunopharmacology 12 (2), 368-377, 2012 | 246 | 2012 |
| Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs) TW Moore, CG Mayne, JA Katzenellenbogen Molecular Endocrinology 24 (4), 683-695, 2010 | 142 | 2010 |
| Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism Y Horie, T Suzuki, J Inoue, T Iso, G Wells, TW Moore, T Mizushima, ... Communications Biology 4 (1), 576, 2021 | 111 | 2021 |
| Stapled peptides with γ‐methylated hydrocarbon chains for the estrogen receptor/coactivator interaction TE Speltz, SW Fanning, CG Mayne, C Fowler, E Tajkhorshid, GL Greene, ... Angewandte Chemie 128 (13), 4324-4327, 2016 | 98 | 2016 |
| Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators AD Jain, H Potteti, BG Richardson, L Kingsley, JP Luciano, AF Ryuzoji, ... European journal of medicinal chemistry 103, 252-268, 2015 | 98 | 2015 |
| Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway BG Richardson, AD Jain, TE Speltz, TW Moore Bioorganic & medicinal chemistry letters 25 (11), 2261-2268, 2015 | 77 | 2015 |
| Selective human estrogen receptor partial agonists (ShERPAs) for tamoxifen-resistant breast cancer R Xiong, HK Patel, LM Gutgesell, J Zhao, L Delgado-Rivera, TND Pham, ... Journal of medicinal chemistry 59 (1), 219-237, 2016 | 70 | 2016 |
| A set of time-resolved fluorescence resonance energy transfer assays for the discovery of inhibitors of estrogen receptor-coactivator binding JR Gunther, Y Du, E Rhoden, I Lewis, B Revennaugh, TW Moore, SH Kim, ... Journal of biomolecular screening 14 (2), 181-193, 2009 | 59 | 2009 |
| Amphipathic benzenes are designed inhibitors of the estrogen receptor α/steroid receptor coactivator interaction JR Gunther, TW Moore, ML Collins, JA Katzenellenbogen ACS chemical biology 3 (5), 282-286, 2008 | 58 | 2008 |
| Discovering Small‐Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High‐Throughput Screening, Ligand Development, and Models for Enhanced Potency A Sun, TW Moore, JR Gunther, MS Kim, E Rhoden, Y Du, H Fu, JP Snyder, ... ChemMedChem 6 (4), 654-666, 2011 | 50 | 2011 |
| Replacement of a naphthalene scaffold in Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor (erythroid-derived 2)-like 2 (NRF2) inhibitors BG Richardson, AD Jain, HR Potteti, PR Lazzara, BP David, CR Tamatam, ... Journal of medicinal chemistry 61 (17), 8029-8047, 2018 | 49 | 2018 |
| Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts S Zhu, TW Moore, X Lin, N Morii, A Mancini, RB Howard, D Culver, ... Integrative Biology 4 (6), 633-640, 2012 | 48 | 2012 |
| Scaffold-hopping as a strategy to address metabolic liabilities of aromatic compounds PR Lazzara, TW Moore RSC Medicinal Chemistry 11 (1), 18-29, 2020 | 42 | 2020 |
| Isoquinoline Kelch-like ECH-associated protein 1-nuclear factor (erythroid-derived 2)-like 2 (KEAP1-NRF2) inhibitors with high metabolic stability PR Lazzara, BP David, A Ankireddy, BG Richardson, K Dye, KM Ratia, ... Journal of medicinal chemistry 63 (12), 6547-6560, 2019 | 42 | 2019 |
| Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties A Brown, Q Shi, TW Moore, Y Yoon, A Prussia, C Maddox, DC Liotta, ... Journal of medicinal chemistry 56 (9), 3456-3466, 2013 | 42 | 2013 |
| Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition M Yamaguchi, TW Moore, A Sun, JP Snyder, M Shoji Integrative Biology 4 (8), 905-913, 2012 | 41 | 2012 |
| A “cross-stitched” peptide with improved helicity and proteolytic stability TE Speltz, CG Mayne, SW Fanning, Z Siddiqui, E Tajkhorshid, GL Greene, ... Organic & biomolecular chemistry 16 (20), 3702-3706, 2018 | 38 | 2018 |
| A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction TE Speltz, JM Danes, JD Stender, J Frasor, TW Moore ACS chemical biology 13 (3), 676-684, 2018 | 35 | 2018 |
| Recent structural advances in constrained helical peptides KJ Skowron, TE Speltz, TW Moore Medicinal research reviews 39 (2), 749-770, 2019 | 31 | 2019 |
| Steroid receptor/coactivator binding inhibitors: An update KJ Skowron, K Booker, C Cheng, S Creed, BP David, PR Lazzara, A Lian, ... Molecular and cellular endocrinology 493, 110471, 2019 | 30 | 2019 |
John KatzenellenbogenUniversity of Illinois at Urbana-ChampaignVerified email at illinois.edu
