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Microbial exposure during early human development primes fetal immune cells
A Mishra, GC Lai, LJ Yao, TT Aung, N Shental, A Rotter-Maskowitz, ...
Cell 184 (13), 3394-3409. e20, 2021
1692021
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections
JJ Koh, S Lin, TT Aung, F Lim, H Zou, Y Bai, J Li, H Lin, LM Pang, WL Koh, ...
Journal of medicinal chemistry 58 (2), 739-752, 2015
1282015
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin, R Lakshminarayanan, X Dai, ...
Journal of medicinal chemistry 56 (6), 2359-2373, 2013
1142013
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin, R Lakshminarayanan, X Dai, ...
Journal of medicinal chemistry 56 (6), 2359-2373, 2013
1142013
Symmetrically substituted xanthone amphiphiles combat gram-positive bacterial resistance with enhanced membrane selectivity
S Lin, JJ Koh, TT Aung, F Lim, J Li, H Zou, L Wang, R Lakshminarayanan, ...
Journal of medicinal chemistry 60 (4), 1362-1378, 2017
772017
Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA)
S Lin, JJ Koh, TT Aung, WLW Sin, F Lim, L Wang, R Lakshminarayanan, ...
Journal of Medicinal Chemistry 60 (14), 6152-6165, 2017
742017
Multifunctional antimicrobial nanofiber dressings containing ε-polylysine for the eradication of bacterial bioburden and promotion of wound healing in critically colonized wounds
V Mayandi, AC Wen Choong, C Dhand, FP Lim, TT Aung, H Sriram, ...
ACS applied materials & interfaces 12 (14), 15989-16005, 2020
732020
Biofilms of pathogenic nontuberculous mycobacteria targeted by new therapeutic approaches
TT Aung, JKH Yam, S Lin, SM Salleh, M Givskov, S Liu, NC Lwin, L Yang, ...
Antimicrobial agents and chemotherapy 60 (1), 24-35, 2016
682016
Antimicrobial activity and cell selectivity of synthetic and biosynthetic cationic polymers
M Venkatesh, VA Barathi, ETL Goh, R Anggara, MHUT Fazil, AJY Ng, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00469-17, 2017
572017
N-lipidated peptide dimers: effective antibacterial agents against gram-negative pathogens through lipopolysaccharide permeabilization
JJ Koh, H Lin, V Caroline, YS Chew, LM Pang, TT Aung, J Li, ...
Journal of medicinal chemistry 58 (16), 6533-6548, 2015
482015
Synthetic multivalent antifungal peptides effective against fungi
R Lakshminarayanan, S Liu, J Li, M Nandhakumar, TT Aung, E Goh, ...
PLoS One 9 (2), e87730, 2014
422014
Surface immobilization of nano-silver on polymeric medical devices to prevent bacterial biofilm formation
AK Riau, TT Aung, M Setiawan, L Yang, G HF Yam, R W. Beuerman, ...
Pathogens 8 (3), 93, 2019
402019
Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the gram-negative bacteria
R Lakshminarayanan, WX Tan, TT Aung, ETL Goh, N Muruganantham, ...
Scientific reports 6 (1), 25905, 2016
352016
Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse …
L Deng, L Wojciech, CW Png, EY Koh, TT Aung, DYQ Kioh, ECY Chan, ...
Cellular and Molecular Life Sciences 79 (5), 245, 2022
302022
Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents
M Yuan, SL Chua, Y Liu, DI Drautz-Moses, JKH Yam, TT Aung, ...
Beilstein journal of organic chemistry 14 (1), 3059-3069, 2018
302018
Collagen-based artificial corneal scaffold with anti-infective capability for prevention of perioperative bacterial infections
AK Riau, D Mondal, TT Aung, E Murugan, L Chen, NC Lwin, L Zhou, ...
ACS Biomaterials Science & Engineering 1 (12), 1324-1334, 2015
262015
Discovery of novel antimycobacterial drug therapy in biofilm of pathogenic nontuberculous mycobacterial keratitis
TT Aung, WHJ Chor, JKH Yam, M Givskov, L Yang, RW Beuerman
The Ocular Surface 15 (4), 770-783, 2017
192017
Antimicrobial activity profiles of amphiphilic xanthone derivatives are a function of their molecular oligomerization
JJ Koh, S Lin, Y Bai, WWL Sin, TT Aung, J Li, V Chandra, K Pervushin, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (11), 2281-2298, 2018
182018
Colonization with two different Blastocystis subtypes in DSS-induced colitis mice is associated with strikingly different microbiome and pathological features
L Deng, L Wojciech, CW Png, DYQ Kioh, Y Gu, TT Aung, B Malleret, ...
Theranostics 13 (3), 1165, 2023
162023
Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis
DSJ Ting, ETL Goh, V Mayandi, JMF Busoy, TT Aung, MH Periayah, ...
Scientific Reports 11 (1), 18304, 2021
152021
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