Long noncoding RNAs: functional surprises from the RNA world JE Wilusz, H Sunwoo, DL Spector Genes & development 23 (13), 1494-1504, 2009 | 2698 | 2009 |
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence M Narita, S Nuñez, E Heard, M Narita, AW Lin, SA Hearn, DL Spector, ... Cell 113 (6), 703-716, 2003 | 2690 | 2003 |
The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, A Revenko, ... Cancer research 73 (3), 1180-1189, 2013 | 1758 | 2013 |
Nuclear speckles: a model for nuclear organelles AI Lamond, DL Spector Nature reviews Molecular cell biology 4 (8), 605-612, 2003 | 1223 | 2003 |
Nuclear speckles DL Spector, AI Lamond Cold Spring Harbor perspectives in biology 3 (2), a000646, 2011 | 999 | 2011 |
Long non-coding RNAs: definitions, functions, challenges and recommendations JS Mattick, PP Amaral, P Carninci, S Carpenter, HY Chang, LL Chen, ... Nature reviews Molecular cell biology 24 (6), 430-447, 2023 | 914 | 2023 |
A long nuclear‐retained non‐coding RNA regulates synaptogenesis by modulating gene expression D Bernard, KV Prasanth, V Tripathi, S Colasse, T Nakamura, Z Xuan, ... The EMBO journal 29 (18), 3082-3093, 2010 | 859 | 2010 |
From silencing to gene expression: real-time analysis in single cells SM Janicki, T Tsukamoto, SE Salghetti, WP Tansey, R Sachidanandam, ... Cell 116 (5), 683-698, 2004 | 814 | 2004 |
3′ end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA JE Wilusz, SM Freier, DL Spector Cell 135 (5), 919-932, 2008 | 800 | 2008 |
Macromolecular domains within the cell nucleus DL Spector Annual review of cell biology 9 (1), 265-315, 1993 | 792 | 1993 |
The dynamics of a pre-mRNA splicing factor in living cells T Misteli, JF Cáceres, DL Spector Nature 387 (6632), 523-527, 1997 | 789 | 1997 |
Cells: a laboratory manual DL Spector, RD Goldman, LA Leinwand Cold Spring Harbor Laboratory Press, 1998 | 778* | 1998 |
Biogenesis and function of nuclear bodies YS Mao, B Zhang, DL Spector Trends in Genetics 27 (8), 295-306, 2011 | 776 | 2011 |
Regulating gene expression through RNA nuclear retention KV Prasanth, SG Prasanth, Z Xuan, S Hearn, SM Freier, CF Bennett, ... Cell 123 (2), 249-263, 2005 | 770 | 2005 |
MEN ε/β nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles H Sunwoo, ME Dinger, JE Wilusz, PP Amaral, JS Mattick, DL Spector Genome research 19 (3), 347-359, 2009 | 714 | 2009 |
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. S Efrat, S Linde, H Kofod, D Spector, M Delannoy, S Grant, D Hanahan, ... Proceedings of the National Academy of Sciences 85 (23), 9037-9041, 1988 | 695 | 1988 |
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility N Dimitrova, YCM Chen, DL Spector, T de Lange Nature 456 (7221), 524-528, 2008 | 648 | 2008 |
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult B Zhang, G Arun, YS Mao, Z Lazar, G Hung, G Bhattacharjee, X Xiao, ... Cell reports 2 (1), 111-123, 2012 | 645 | 2012 |
Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation E Heard, C Rougeulle, D Arnaud, P Avner, CD Allis, DL Spector Cell 107 (6), 727-738, 2001 | 638 | 2001 |
Associations between distinct pre‐mRNA splicing components and the cell nucleus. DL Spector, XD Fu, T Maniatis The EMBO journal 10 (11), 3467-3481, 1991 | 634 | 1991 |