| Ferroptosis: mechanisms and links with diseases H Yan, T Zou, Q Tuo, S Xu, H Li, AA Belaidi, P Lei Signal transduction and targeted therapy 6 (1), 49, 2021 | 626 | 2021 |
| Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ... Nature Medicine 18 (2), 291-295, 2012 | 619 | 2012 |
| Tau-mediated iron export prevents ferroptotic damage after ischemic stroke QZ Tuo, P Lei, KA Jackman, XL Li, H Xiong, ZY Liuyang, L Roisman, ... Molecular psychiatry 22 (11), 1520-1530, 2017 | 529 | 2017 |
| A delicate balance: Iron metabolism and diseases of the brain D Hare, S Ayton, A Bush, P Lei Frontiers in aging neuroscience 5, 34, 2013 | 413 | 2013 |
| Metallostasis in Alzheimer's disease S Ayton, P Lei, AI Bush Free Radical Biology and Medicine 62, 76-89, 2013 | 380 | 2013 |
| Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications Q Tuo, S Zhang, P Lei Medicinal research reviews 42 (1), 259-305, 2022 | 275 | 2022 |
| Ceruloplasmin dysfunction and therapeutic potential for parkinson's disease S Ayton, P Lei, JA Duce, BXW Wong, A Sedjahtera, PA Adlard, AI Bush, ... Annals of Neurology, 2012 | 268 | 2012 |
| Tau protein: relevance to Parkinson's disease P Lei, S Ayton, DI Finkelstein, PA Adlard, CL Masters, AI Bush The international journal of biochemistry & cell biology 42 (11), 1775-1778, 2010 | 247 | 2010 |
| The essential elements of Alzheimer’s disease P Lei, S Ayton, AI Bush Journal of Biological Chemistry 296, 2021 | 205 | 2021 |
| GSK-3 in neurodegenerative diseases P Lei, S Ayton, AI Bush, PA Adlard International journal of Alzheimer’s disease 2011, 2011 | 183 | 2011 |
| The pathological role of ferroptosis in ischemia/reperfusion-related injury HF Yan, QZ Tuo, QZ Yin, P Lei Zoological research 41 (3), 220, 2020 | 170 | 2020 |
| Nigral iron elevation is an invariable feature of Parkinson’s disease and is a sufficient cause of neurodegeneration S Ayton, P Lei BioMed research international 2014, 2014 | 160 | 2014 |
| Motor and cognitive deficits in aged tau knockout mice in two background strains P Lei, S Ayton, S Moon, Q Zhang, I Volitakis, DI Finkelstein, AI Bush Molecular neurodegeneration 9, 1-12, 2014 | 148 | 2014 |
| Ferroptosis, a recent defined form of critical cell death in neurological disorders J Wu, Q Tuo, P Lei Journal of Molecular Neuroscience 66 (2), 197-206, 2018 | 147 | 2018 |
| Sequestration of copper from β-amyloid promotes selective lysis by cyclen-hybrid cleavage agents W Wu, P Lei, Q Liu, J Hu, AP Gunn, M Chen, Y Rui, X Su, Z Xie, YF Zhao, ... Journal of Biological Chemistry 283 (46), 31657-31664, 2008 | 137 | 2008 |
| Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein S Ayton, P Lei, DJ Hare, JA Duce, JL George, PA Adlard, C McLean, ... Journal of Neuroscience 35 (8), 3591-3597, 2015 | 134 | 2015 |
| Biometals and their therapeutic implications in Alzheimer's disease S Ayton, P Lei, AI Bush Neurotherapeutics 12 (1), 109-120, 2015 | 134 | 2015 |
| Characterization of copper binding to the peptide amyloid‐β (1–16) associated with Alzheimer's disease QF Ma, J Hu, WH Wu, HD Liu, JT Du, Y Fu, YW Wu, P Lei, YF Zhao, YM Li Biopolymers: Original Research on Biomolecules 83 (1), 20-31, 2006 | 123 | 2006 |
| An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta DJ Hare, P Lei, S Ayton, BR Roberts, R Grimm, JL George, DP Bishop, ... Chemical Science 5 (6), 2160-2169, 2014 | 113 | 2014 |
| Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion Q Tuo, Y Liu, Z Xiang, HF Yan, T Zou, Y Shu, X Ding, J Zou, S Xu, F Tang, ... Signal transduction and targeted therapy 7 (1), 59, 2022 | 108 | 2022 |
Ashley BushMassachusetts General Hospital, Florey Institute of Neuroscience & Mental HealthVerified email at helix.mgh.harvard.edu
