| Structural basis for gluten intolerance in celiac sprue L Shan, Ø Molberg, I Parrot, F Hausch, F Filiz, GM Gray, LM Sollid, ... Science 297 (5590), 2275-2279, 2002 | 2078 | 2002 |
| A new enzyme superfamily—the phosphopantetheinyl transferases RH Lambalot, AM Gehring, RS Flugel, P Zuber, M LaCelle, MA Marahiel, ... Chemistry & biology 3 (11), 923-936, 1996 | 1124 | 1996 |
| Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli BA Pfeifer, SJ Admiraal, H Gramajo, DE Cane, C Khosla Science 291 (5509), 1790-1792, 2001 | 974 | 2001 |
| Harnessing the biosynthetic code: combinations, permutations, and mutations DE Cane, CT Walsh, C Khosla Science 282 (5386), 63-68, 1998 | 885 | 1998 |
| Engineered biosynthesis of novel polyketides R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla Science 262 (5139), 1546-1550, 1993 | 618 | 1993 |
| Cloning and heterologous expression of the epothilone gene cluster L Tang, S Shah, L Chung, J Carney, L Katz, C Khosla, B Julien Science 287 (5453), 640-642, 2000 | 576 | 2000 |
| Transglutaminase 2 undergoes a large conformational change upon activation DM Pinkas, P Strop, AT Brunger, C Khosla PLoS biology 5 (12), e327, 2007 | 536 | 2007 |
| Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease CY Kim, H Quarsten, E Bergseng, C Khosla, LM Sollid Proceedings of the National Academy of Sciences 101 (12), 4175-4179, 2004 | 531 | 2004 |
| Intestinal digestive resistance of immunodominant gliadin peptides F Hausch, L Shan, NA Santiago, GM Gray, C Khosla American Journal of Physiology-Gastrointestinal and Liver Physiology 283 (4 …, 2002 | 515 | 2002 |
| Overproduction of free fatty acids in E. coli: implications for biodiesel production X Lu, H Vora, C Khosla Metabolic engineering 10 (6), 333-339, 2008 | 499 | 2008 |
| Tolerance and specificity of polyketide synthases C Khosla, RS Gokhale, JR Jacobsen, DE Cane Annual review of biochemistry 68 (1), 219-253, 1999 | 481 | 1999 |
| Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease R Bouziat, R Hinterleitner, JJ Brown, JE Stencel-Baerenwald, M Ikizler, ... Science 356 (6333), 44-50, 2017 | 471 | 2017 |
| Dissecting and exploiting intermodular communication in polyketide synthases RS Gokhale, SY Tsuji, DE Cane, C Khosla Science 284 (5413), 482-485, 1999 | 441 | 1999 |
| Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds CT Walsh, RV O'Brien, C Khosla Angewandte Chemie International Edition 52 (28), 7098-7124, 2013 | 404 | 2013 |
| Biosynthesis of polyketides in heterologous hosts BA Pfeifer, C Khosla Microbiology and Molecular Biology Reviews 65 (1), 106-118, 2001 | 396 | 2001 |
| Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase JR Jacobsen, CR Hutchinson, DE Cane, C Khosla Science 277 (5324), 367-369, 1997 | 391 | 1997 |
| Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue L Shan, SW Qiao, H Arentz-Hansen, Ø Molberg, GM Gray, LM Sollid, ... Journal of proteome research 4 (5), 1732-1741, 2005 | 375 | 2005 |
| Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla Nature 375 (6532), 549-554, 1995 | 372 | 1995 |
| Structure and mechanism of the 6-deoxyerythronolide B synthase C Khosla, Y Tang, AY Chen, NA Schnarr, DE Cane Annu. Rev. Biochem. 76 (1), 195-221, 2007 | 365 | 2007 |
| The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase Y Tang, CY Kim, II Mathews, DE Cane, C Khosla Proceedings of the National Academy of Sciences 103 (30), 11124-11129, 2006 | 354 | 2006 |
