| Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 5953 | 2015 |
| Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10 ML Maeder, M Stefanidakis, CJ Wilson, R Baral, LA Barrera, ... Nature medicine 25 (2), 229-233, 2019 | 615 | 2019 |
| Directed evolution of adenine base editors with increased activity and therapeutic application NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ... Nature biotechnology 38 (7), 892-900, 2020 | 419 | 2020 |
| UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions MA Hume, LA Barrera, SS Gisselbrecht, ML Bulyk Nucleic acids research 43 (D1), D117-D122, 2015 | 306 | 2015 |
| Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus A Bothmer, T Phadke, LA Barrera, CM Margulies, CS Lee, F Buquicchio, ... Nature communications 8 (1), 13905, 2017 | 205 | 2017 |
| Survey of variation in human transcription factors reveals prevalent DNA binding changes LA Barrera, A Vedenko, JV Kurland, JM Rogers, SS Gisselbrecht, ... Science 351 (6280), 1450-1454, 2016 | 180 | 2016 |
| The NF-κB genomic landscape in lymphoblastoid B cells B Zhao, LA Barrera, I Ersing, B Willox, SCS Schmidt, H Greenfeld, H Zhou, ... Cell reports 8 (5), 1595-1606, 2014 | 163 | 2014 |
| Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity Y Yu, TC Leete, DA Born, L Young, LA Barrera, SJ Lee, HA Rees, ... Nature Communications 11 (1), 2052, 2020 | 162 | 2020 |
| Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing X Zhang, W Zhao, GN Nguyen, C Zhang, C Zeng, J Yan, S Du, X Hou, ... Science advances 6 (34), eabc2315, 2020 | 121 | 2020 |
| UDiTaS™, a genome editing detection method for indels and genome rearrangements G Giannoukos, DM Ciulla, E Marco, HS Abdulkerim, LA Barrera, ... BMC genomics 19, 1-10, 2018 | 117 | 2018 |
| Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos SS Gisselbrecht, LA Barrera, M Porsch, A Aboukhalil, PW Estep III, ... Nature methods 10 (8), 774-780, 2013 | 77 | 2013 |
| Rationally designed base editors for precise editing of the sickle cell disease mutation SH Chu, M Packer, H Rees, D Lam, Y Yu, J Marshall, LI Cheng, D Lam, ... The CRISPR Journal 4 (2), 169-177, 2021 | 66 | 2021 |
| Cytosine base editing enables quadruple-edited allogeneic CART cells for T-ALL C Diorio, R Murray, M Naniong, L Barrera, A Camblin, J Chukinas, ... Blood, The Journal of the American Society of Hematology 140 (6), 619-629, 2022 | 49 | 2022 |
| EpiFire: An open source C++ library and application for contact network epidemiology T Hladish, E Melamud, LA Barrera, A Galvani, LA Meyers BMC bioinformatics 13, 1-12, 2012 | 49 | 2012 |
| Identification of human lineage-specific transcriptional coregulators enabled by a glossary of binding modules and tunable genomic backgrounds L Mariani, K Weinand, A Vedenko, LA Barrera, ML Bulyk Cell systems 5 (3), 187-201. e7, 2017 | 45 | 2017 |
| Context influences on TALE–DNA binding revealed by quantitative profiling JM Rogers, LA Barrera, D Reyon, JD Sander, M Kellis, J Keith Joung, ... Nature communications 6 (1), 7440, 2015 | 44 | 2015 |
| Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo” CJ Wilson, T Fennell, A Bothmer, ML Maeder, D Reyon, ... Nature methods 15 (4), 236-237, 2018 | 38 | 2018 |
| Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells J Tycko, LA Barrera, NC Huston, AE Friedland, X Wu, JS Gootenberg, ... Nature communications 9 (1), 2962, 2018 | 34 | 2018 |
| CellMapper: rapid and accurate inference of gene expression in difficult-to-isolate cell types BD Nelms, L Waldron, LA Barrera, AW Weflen, JA Goettel, G Guo, ... Genome biology 17, 1-13, 2016 | 32 | 2016 |
| PEARL-seq: a photoaffinity platform for the analysis of small molecule-RNA interactions H Mukherjee, JC Blain, LE Vandivier, DN Chin, JE Friedman, F Liu, ... ACS Chemical Biology 15 (9), 2374-2381, 2020 | 30 | 2020 |
