| Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy GP Gao, MR Alvira, L Wang, R Calcedo, J Johnston, JM Wilson Proceedings of the National Academy of Sciences 99 (18), 11854-11859, 2002 | 1968 | 2002 |
| Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a … WW Hauswirth, TS Aleman, S Kaushal, AV Cideciyan, SB Schwartz, ... Human gene therapy 19 (10), 979-990, 2008 | 1177 | 2008 |
| A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice Y Yang, L Wang, P Bell, D McMenamin, Z He, J White, H Yu, C Xu, ... Nature biotechnology 34 (3), 334-338, 2016 | 618 | 2016 |
| Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery M Hoshijima, Y Ikeda, Y Iwanaga, S Minamisawa, M Date, Y Gu, ... Nature medicine 8 (8), 864-871, 2002 | 466 | 2002 |
| Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy ML Brantly, JD Chulay, L Wang, C Mueller, M Humphries, LT Spencer, ... Proceedings of the National Academy of Sciences 106 (38), 16363-16368, 2009 | 377 | 2009 |
| Adeno-associated virus antibody profiles in newborns, children, and adolescents R Calcedo, H Morizono, L Wang, R McCarter, J He, D Jones, ML Batshaw, ... Clinical and Vaccine Immunology 18 (9), 1586-1588, 2011 | 329 | 2011 |
| Sustained correction of bleeding disorder in hemophilia B mice by gene therapy L Wang, K Takabe, SM Bidlingmaier, CR Ill, IM Verma Proceedings of the National Academy of Sciences 96 (7), 3906-3910, 1999 | 293 | 1999 |
| Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype R Sarkar, R Tetreault, G Gao, L Wang, P Bell, R Chandler, JM Wilson, ... Blood 103 (4), 1253-1260, 2004 | 271 | 2004 |
| Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer M Hildinger, A Auricchio, G Gao, L Wang, N Chirmule, JM Wilson Journal of virology 75 (13), 6199-6203, 2001 | 264 | 2001 |
| Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey LH Vandenberghe, P Bell, AM Maguire, CN Cearley, R Xiao, R Calcedo, ... Science translational medicine 3 (88), 88ra54-88ra54, 2011 | 252 | 2011 |
| Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid LH Vandenberghe, L Wang, S Somanathan, Y Zhi, J Figueredo, ... Nature medicine 12 (8), 967-971, 2006 | 250 | 2006 |
| Efficacy and safety of adeno‐associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy T Vandendriessche, L Thorrez, A Acosta‐Sanchez, I Petrus, L Wang, L Ma, ... Journal of Thrombosis and Haemostasis 5 (1), 16-24, 2007 | 249 | 2007 |
| Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver L Wang, TC Nichols, MS Read, DA Bellinger, IM Verma Molecular therapy 1 (2), 154-158, 2000 | 228 | 2000 |
| Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy L Wang, R Calcedo, TC Nichols, DA Bellinger, A Dillow, IM Verma, ... Blood 105 (8), 3079-3086, 2005 | 212 | 2005 |
| Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates G Gao, Y Lu, R Calcedo, RL Grant, P Bell, L Wang, J Figueredo, M Lock, ... Molecular Therapy 13 (1), 77-87, 2006 | 205 | 2006 |
| A factor IX-deficient mouse model for hemophilia B gene therapy L Wang, M Zoppè, TM Hackeng, JH Griffin, KF Lee, IM Verma Proceedings of the National Academy of Sciences 94 (21), 11563-11566, 1997 | 201 | 1997 |
| Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors L Wang, R Calcedo, P Bell, J Lin, RL Grant, DL Siegel, JM Wilson Human gene therapy 22 (11), 1389-1401, 2011 | 197 | 2011 |
| In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification DL Glaser, AN Economides, L Wang, X Liu, RD Kimble, JP Fandl, ... JBJS 85 (12), 2332-2342, 2003 | 177 | 2003 |
| Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins A Auricchio, E O’Connor, D Weiner, GP Gao, M Hildinger, L Wang, ... The Journal of clinical investigation 110 (4), 499-504, 2002 | 175 | 2002 |
| No evidence for tumorigenesis of AAV vectors in a large-scale study in mice P Bell, L Wang, C Lebherz, DB Flieder, MS Bove, D Wu, GP Gao, ... Molecular therapy 12 (2), 299-306, 2005 | 159 | 2005 |
GuangPing GaoVerified email at umassmed.edu
