Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ... Cancer cell 22 (5), 585-600, 2012 | 425 | 2012 |
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex J Fan, C Shan, HB Kang, S Elf, J Xie, M Tucker, TL Gu, M Aguiar, ... Molecular cell 53 (4), 534-548, 2014 | 286 | 2014 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484-1496, 2015 | 261 | 2015 |
Mitochondrial Akt regulation of hypoxic tumor reprogramming YC Chae, V Vaira, MC Caino, HY Tang, JH Seo, AV Kossenkov, ... Cancer cell 30 (2), 257-272, 2016 | 197 | 2016 |
Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ... Molecular cell 59 (3), 345-358, 2015 | 143 | 2015 |
The mitochondrial unfoldase-peptidase complex ClpXP controls bioenergetics stress and metastasis JH Seo, DB Rivadeneira, MC Caino, YC Chae, DW Speicher, HY Tang, ... PLoS biology 14 (7), e1002507, 2016 | 139 | 2016 |
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 139 | 2014 |
A neuronal network of mitochondrial dynamics regulates metastasis MC Caino, JH Seo, A Aguinaldo, E Wait, KG Bryant, AV Kossenkov, ... Nature communications 7 (1), 13730, 2016 | 122 | 2016 |
Adaptive mitochondrial reprogramming and resistance to PI3K therapy JC Ghosh, MD Siegelin, V Vaira, A Faversani, M Tavecchio, YC Chae, ... Journal of the National Cancer Institute 107 (3), dju502, 2015 | 113 | 2015 |
Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion DB Rivadeneira, MC Caino, JH Seo, A Angelin, DC Wallace, ... Science signaling 8 (389), ra80-ra80, 2015 | 106 | 2015 |
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, ... Nature communications 4 (1), 1790, 2013 | 95 | 2013 |
An artificial intelligence model to predict the mortality of COVID-19 patients at hospital admission time using routine blood samples: development and validation of an ensemble … H Ko, H Chung, WS Kang, C Park, DW Kim, SE Kim, CR Chung, RE Ko, ... Journal of medical Internet research 22 (12), e25442, 2020 | 74 | 2020 |
The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor … D Li, L Jin, GN Alesi, YM Kim, J Fan, JH Seo, D Wang, M Tucker, TL Gu, ... Journal of Biological Chemistry 288 (45), 32528-32538, 2013 | 60 | 2013 |
The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells J Li, E Agarwal, I Bertolini, JH Seo, MC Caino, JC Ghosh, AV Kossenkov, ... Science signaling 13 (642), eaaz8240, 2020 | 59 | 2020 |
Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nα-terminal acetylation of human peroxiredoxin II JH Seo, JC Lim, DY Lee, KS Kim, G Piszczek, HW Nam, YS Kim, T Ahn, ... Journal of biological chemistry 284 (20), 13455-13465, 2009 | 53 | 2009 |
Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements JH Seo, E Agarwal, KG Bryant, MC Caino, ET Kim, AV Kossenkov, ... Cancer research 78 (15), 4215-4228, 2018 | 51 | 2018 |
Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer MC Caino, JH Seo, Y Wang, DB Rivadeneira, DI Gabrilovich, ET Kim, ... The Journal of clinical investigation 127 (10), 3755-3769, 2017 | 44 | 2017 |
MFF regulation of mitochondrial cell death is a therapeutic target in cancer JH Seo, YC Chae, AV Kossenkov, YG Lee, HY Tang, E Agarwal, ... Cancer research 79 (24), 6215-6226, 2019 | 42 | 2019 |
Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits JC Ghosh, JH Seo, E Agarwal, Y Wang, AV Kossenkov, HY Tang, ... Oncogene 38 (43), 6926-6939, 2019 | 40 | 2019 |
Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer JH Seo, E Agarwal, YC Chae, YG Lee, DS Garlick, AM Storaci, S Ferrero, ... EBioMedicine 48, 353-363, 2019 | 39 | 2019 |