Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution D Ahuatzi, A Riera, R Pela, P Herrero, F Moreno Journal of Biological Chemistry 282 (7), 4485-4493, 2007 | 197 | 2007 |
Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA J Sun, C Evrin, SA Samel, A Fernández-Cid, A Riera, H Kawakami, ... Nature structural & molecular biology 20 (8), 944-951, 2013 | 162 | 2013 |
An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly A Fernández-Cid, A Riera, S Tognetti, MC Herrera, S Samel, C Evrin, ... Molecular cell 50 (4), 577-588, 2013 | 154 | 2013 |
Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1 Z Yuan, A Riera, L Bai, J Sun, S Nandi, C Spanos, ZA Chen, M Barbon, ... Nature structural & molecular biology 24 (3), 316-324, 2017 | 142 | 2017 |
Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function J Sun, A Fernandez-Cid, A Riera, S Tognetti, Z Yuan, B Stillman, C Speck, ... Genes & development 28 (20), 2291-2303, 2014 | 123 | 2014 |
A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA SA Samel, A Fernández-Cid, J Sun, A Riera, S Tognetti, MC Herrera, H Li, ... Genes & development 28 (15), 1653-1666, 2014 | 117 | 2014 |
Glucose sensing through the Hxk2-dependent signalling pathway F Moreno, D Ahuatzi, A Riera, CA Palomino, P Herrero Biochemical Society Transactions 33 (1), 265-268, 2005 | 113 | 2005 |
From structure to mechanism—understanding initiation of DNA replication A Riera, M Barbon, Y Noguchi, LM Reuter, S Schneider, C Speck Genes & development 31 (11), 1073-1088, 2017 | 102 | 2017 |
Hexokinase 2 is an intracellular glucose sensor of yeast cells that maintains the structure and activity of Mig1 protein repressor complex M Vega, A Riera, A Fernández-Cid, P Herrero, F Moreno Journal of Biological Chemistry 291 (14), 7267-7285, 2016 | 95 | 2016 |
Switch on the engine: how the eukaryotic replicative helicase MCM2–7 becomes activated S Tognetti, A Riera, C Speck Chromosoma 124 (1), 13-26, 2015 | 54 | 2015 |
In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2–7 hexamer dimerization C Evrin, A Fernandez-Cid, J Zech, MC Herrera, A Riera, P Clarke, S Brill, ... Nucleic acids research 41 (5), 3162-3172, 2013 | 52 | 2013 |
Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 Z Yuan, S Schneider, T Dodd, A Riera, L Bai, C Yan, M Barbon, ... Proceedings of the National Academy of Sciences 117 (30), 17747-17756, 2020 | 41 | 2020 |
The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation C Evrin, A Fernandez-Cid, A Riera, J Zech, P Clarke, MC Herrera, ... Nucleic acids research 42 (4), 2257-2269, 2014 | 41 | 2014 |
Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication FJ Chang, A Riera, C Evrin, J Sun, H Li, C Speck, M Weinreich Elife 4, e05795, 2015 | 36 | 2015 |
Helicase loading: how to build a MCM2-7 double-hexamer A Riera, S Tognetti, C Speck Seminars in cell & developmental biology 30, 104-109, 2014 | 36 | 2014 |
A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase MC Herrera, S Tognetti, A Riera, J Zech, P Clarke, A Fernández-Cid, ... Nucleic acids research 43 (21), 10238-10250, 2015 | 13 | 2015 |
Glucose levels regulate the nucleo-mitochondrial distribution of Mig2 A Fernández-Cid, A Riera, P Herrero, F Moreno Mitochondrion 12 (3), 370-380, 2012 | 13 | 2012 |
Human pancreatic β-cell glucokinase: subcellular localization and glucose repression signalling function in the yeast cell A Riera, D Ahuatzi, P Herrero, MA Garcia-Gimeno, P Sanz, F Moreno Biochemical Journal 415 (2), 233-239, 2008 | 8 | 2008 |
Opening the gate to DNA replication A Riera, C Speck Cell cycle 14 (1), 6-8, 2015 | 7 | 2015 |
Seeing is believing: The MCM2–7 helicase trapped in complex with its DNA loader A Riera, H Li, C Speck Cell Cycle 12 (18), 2917-2918, 2013 | 7 | 2013 |