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Amer Alam
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Cited by
Year
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein
A Alam, J Kowal, E Broude, I Roninson, KP Locher
Science 363 (6428), 753-756, 2019
3652019
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
I Dulubova, X Lou, J Lu, I Huryeva, A Alam, R Schneggenburger, ...
The EMBO journal 24 (16), 2839-2850, 2005
3262005
Atomic structure of a Na+- and K+-conducting channel
N Shi, S Ye, A Alam, L Chen, Y Jiang
Nature 440 (7083), 570-574, 2006
2922006
Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1
A Alam, R Küng, J Kowal, RA McLeod, N Tremp, EV Broude, IB Roninson, ...
Proceedings of the National Academy of Sciences 115 (9), E1973-E1982, 2018
1702018
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1
K Nosol, K Romane, RN Irobalieva, A Alam, J Kowal, N Fujita, KP Locher
Proceedings of the National Academy of Sciences 117 (42), 26245-26253, 2020
1572020
High-resolution structure of the open NaK channel
A Alam, Y Jiang
Nature structural & molecular biology 16 (1), 30-34, 2009
1532009
Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites
MG Derebe, DB Sauer, W Zeng, A Alam, N Shi, Y Jiang
Proceedings of the National Academy of Sciences 108 (2), 598-602, 2011
1272011
Structural analysis of ion selectivity in the NaK channel
A Alam, Y Jiang
Nature structural & molecular biology 16 (1), 35-41, 2009
1102009
Structure of the human lipid exporter ABCB4 in a lipid environment
JA Olsen, A Alam, J Kowal, B Stieger, KP Locher
Nature structural & molecular biology 27 (1), 62-70, 2020
722020
Structural basis of transcobalamin recognition by human CD320 receptor
A Alam, JS Woo, J Schmitz, B Prinz, K Root, F Chen, JS Bloch, R Zenobi, ...
Nature communications 7 (1), 12100, 2016
482016
Structural insight into Ca2+ specificity in tetrameric cation channels
A Alam, N Shi, Y Jiang
Proceedings of the National Academy of Sciences 104 (39), 15334-15339, 2007
472007
Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore
MG Derebe, W Zeng, Y Li, A Alam, Y Jiang
Proceedings of the National Academy of Sciences 108 (2), 592-597, 2011
452011
Structural studies of ion selectivity in tetrameric cation channels
A Alam, Y Jiang
Journal of General Physiology 137 (5), 397-403, 2011
412011
Structure and mechanism of human ABC transporters
A Alam, KP Locher
Annual Review of Biophysics 52, 275-300, 2023
242023
ABCA7 regulates brain fatty acid metabolism during LPS-induced acute inflammation
T Aikawa, Y Ren, ML Holm, YW Asmann, A Alam, ML Fitzgerald, G Bu, ...
Frontiers in Neuroscience 15, 647974, 2021
132021
Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
LTM Le, JR Thompson, PX Dang, J Bhandari, A Alam
Communications biology 5 (1), 7, 2022
102022
Cryo-EM structure of lipid embedded human ABCA7 at 3.6 Å resolution
LTM Le, JR Thompson, T Aikawa, T Kanikeyo, A Alam
BioRxiv, 2021
62021
Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms
LTM Le, JR Thompson, S Dehghani‐Ghahnaviyeh, S Pant, PX Dang, ...
The EMBO Journal 42 (3), e111065, 2023
52023
Measuring lipid transfer protein activity using Bicelle-Dilution model membranes
YG Gao, LT My Le, X Zhai, IA Boldyrev, SK Mishra, A Tischer, ...
Analytical chemistry 92 (4), 3417-3425, 2020
42020
A Simple and Straightforward Approach for Generating Small, Stable, Homogeneous, Unilamellar 1-Palmitoyl 2-Oleoyl Phosphatidylcholine (POPC) Bilayer Vesicles
YG Gao, A Alam, RE Brown
Bio-protocol 11 (24), e4271-e4271, 2021
22021
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Articles 1–20