Importance of oestrogen receptors to preserve functional β-cell mass in diabetes JP Tiano, F Mauvais-Jarvis Nature Reviews Endocrinology 8 (6), 342-351, 2012 | 243 | 2012 |
Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes JP Tiano, V Delghingaro-Augusto, C Le May, S Liu, MK Kaw, SS Khuder, ... The Journal of clinical investigation 121 (8), 3331-3342, 2011 | 196 | 2011 |
Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis WPS Wong, JP Tiano, S Liu, SC Hewitt, C Le May, S Dalle, ... Proceedings of the National Academy of Sciences 107 (29), 13057-13062, 2010 | 157 | 2010 |
Early-life exposure to testosterone programs the hypothalamic melanocortin system K Nohara, Y Zhang, RS Waraich, A Laque, JP Tiano, J Tong, H Münzberg, ... Endocrinology 152 (4), 1661-1669, 2011 | 145 | 2011 |
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise JP Tiano, DA Springer, SG Rane Journal of Biological Chemistry 290 (12), 7671-7684, 2015 | 110 | 2015 |
Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress Z Zhou, V Ribas, P Rajbhandari, BG Drew, TM Moore, AH Fluitt, ... Journal of Biological Chemistry 293 (13), 4735-4751, 2018 | 89 | 2018 |
Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells JP Tiano, F Mauvais-Jarvis Endocrinology 153 (7), 2997-3005, 2012 | 60 | 2012 |
Effect of targeted estrogen delivery using glucagon-like peptide-1 on insulin secretion, insulin sensitivity and glucose homeostasis JP Tiano, CR Tate, BS Yang, R DiMarchi, F Mauvais-Jarvis Scientific reports 5 (1), 10211, 2015 | 39 | 2015 |
Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes JP Tiano, F Mauvais-Jarvis Islets 4 (2), 173-176, 2012 | 32 | 2012 |
The role of estrogens in pancreatic islet physiopathology F Mauvais-Jarvis, C Le May, JP Tiano, S Liu, G Kilic-Berkmen, JH Kim Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity …, 2017 | 30 | 2017 |
Efficacy of glucagon-like peptide-1 and estrogen dual agonist in pancreatic islets protection and pre-clinical models of insulin-deficient diabetes T Fuselier, PM de Sa, MMF Qadir, B Xu, C Allard, MM Meyers, JP Tiano, ... Cell Reports Medicine 3 (4), 2022 | 13 | 2022 |
Mitogen‐associated protein kinase‐and protein kinase A‐dependent regulation of rhodopsin promoter expression in zebrafish rod photoreceptor cells CJ Yu, Y Gao, CL Willis, P Li, JP Tiano, PA Nakamura, DR Hyde, L Li Journal of neuroscience research 85 (3), 488-496, 2007 | 13 | 2007 |
Kisspeptin and glucose homeostasis C Izzi-Engbeaya, TG Hill, JE Bowe Seminars in Reproductive Medicine 37 (03), 141-146, 2019 | 8 | 2019 |
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and PGC-1alpha during exercise JP Tiano, DA Springer, SG Rane J. Biol. Chem 290 (18), 11431, 2015 | 6 | 2015 |
A glucagon-like peptide-1-estrogen fusion peptide shows enhanced efficacy in preventing insulin-deficient diabetes in mice J Tiano, B Finan, R DiMarchi, F Mauvais-Jarvis Endocr Rev 33, OR21-OR26, 2012 | 3 | 2012 |
Estrogen Receptor α Protects Pancreatic β-cells from Apoptosis by Preserving Mitochondrial Function and Suppressing Endoplasmic Reticulum Stress Zhenqi Zhou1, Vicent Ribas1 … M Liesa, O Shirihai, AM van der Bliek, NW Chi, SK Mahata, JP Tiano, ... | | 2018 |
Extranuclear estrogen receptor-αstimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis WPS Wong, JP Tiano, S Liu, SC Hewitt, C Le May, Sà Dalle, ... | | 2015 |
Transforming Growth Factor-Beta Is Negatively Associated with Irisin in Exercised Obese Mice JP Tiano, DA Springer, SG Rane ENDOCRINE REVIEWS 35 (3), 2014 | | 2014 |
Estrogen Receptor Activation Suppresses Lipogenesis and Reduces Lipid Accumulation in Pancreatic Islets and Prevents Lipotoxic beta-cell Failure JP Tiano Northwestern University, 2012 | | 2012 |