Tackling the widespread and critical impact of batch effects in high-throughput data JT Leek, RB Scharpf, HC Bravo, D Simcha, B Langmead, WE Johnson, ... Nature Reviews Genetics 11 (10), 733-739, 2010 | 2172 | 2010 |
Neoadjuvant PD-1 blockade in resectable lung cancer PM Forde, JE Chaft, KN Smith, V Anagnostou, TR Cottrell, MD Hellmann, ... New England Journal of Medicine 378 (21), 1976-1986, 2018 | 2027 | 2018 |
Genome-wide association study of blood pressure and hypertension D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer, A Dehghan, ... Nature genetics 41 (6), 677-687, 2009 | 1646 | 2009 |
Direct detection of early-stage cancers using circulating tumor DNA J Phallen, M Sausen, V Adleff, A Leal, C Hruban, J White, V Anagnostou, ... Science translational medicine 9 (403), eaan2415, 2017 | 1099 | 2017 |
Genome-wide cell-free DNA fragmentation in patients with cancer S Cristiano, A Leal, J Phallen, J Fiksel, V Adleff, DC Bruhm, SØ Jensen, ... Nature 570 (7761), 385-389, 2019 | 994 | 2019 |
Evolution of neoantigen landscape during immune checkpoint blockade in non–small cell lung cancer V Anagnostou, KN Smith, PM Forde, N Niknafs, R Bhattacharya, J White, ... Cancer discovery 7 (3), 264-276, 2017 | 876 | 2017 |
Multiple loci associated with indices of renal function and chronic kidney disease A Köttgen, NL Glazer, A Dehghan, SJ Hwang, R Katz, M Li, Q Yang, ... Nature genetics 41 (6), 712-717, 2009 | 772 | 2009 |
High grade serous ovarian carcinomas originate in the fallopian tube SI Labidi-Galy, E Papp, D Hallberg, N Niknafs, V Adleff, M Noe, ... Nature communications 8 (1), 1093, 2017 | 727 | 2017 |
Detectable clonal mosaicism from birth to old age and its relationship to cancer CC Laurie, CA Laurie, K Rice, KF Doheny, LR Zelnick, CP McHugh, ... Nature genetics 44 (6), 642-650, 2012 | 658 | 2012 |
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients. Nature Communications 6, 2015 | 485 | 2015 |
The genomic landscape of response to EGFR blockade in colorectal cancer A Bertotti, E Papp, S Jones, V Adleff, V Anagnostou, B Lupo, M Sausen, ... Nature 526 (7572), 263-267, 2015 | 483 | 2015 |
Detection and characterization of lung cancer using cell-free DNA fragmentomes D Mathios, JS Johansen, S Cristiano, JE Medina, J Phallen, KR Larsen, ... Nature communications 12 (1), 5060, 2021 | 281 | 2021 |
Dynamics of tumor and immune responses during immune checkpoint blockade in non–small cell lung cancer V Anagnostou, PM Forde, JR White, N Niknafs, C Hruban, J Naidoo, ... Cancer research 79 (6), 1214-1225, 2019 | 281 | 2019 |
Pre-processing Agilent microarray data M Zahurak, G Parmigiani, W Yu, RB Scharpf, D Berman, E Schaeffer, ... BMC bioinformatics 8, 1-13, 2007 | 256 | 2007 |
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models H Kim, H Xu, E George, D Hallberg, S Kumar, V Jagannathan, ... Nature communications 11 (1), 3726, 2020 | 246 | 2020 |
White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer A Leal, NCT van Grieken, DN Palsgrove, J Phallen, JE Medina, C Hruban, ... Nature communications 11 (1), 525, 2020 | 210 | 2020 |
Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer V Anagnostou, N Niknafs, K Marrone, DC Bruhm, JR White, J Naidoo, ... Nature cancer 1 (1), 99-111, 2020 | 178 | 2020 |
Regulation of platelet granule exocytosis by S-nitrosylation CN Morrell, K Matsushita, K Chiles, RB Scharpf, M Yamakuchi, ... Proceedings of the National Academy of Sciences 102 (10), 3782-3787, 2005 | 158 | 2005 |
Genomic characterization of malignant progression in neoplastic pancreatic cysts M Noë, N Niknafs, CG Fischer, WM Hackeng, V Beleva Guthrie, ... Nature communications 11 (1), 4085, 2020 | 118 | 2020 |
Early noninvasive detection of response to targeted therapy in non–small cell lung cancer J Phallen, A Leal, BD Woodward, PM Forde, J Naidoo, KA Marrone, ... Cancer research 79 (6), 1204-1213, 2019 | 109 | 2019 |