Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System S Santaguida, A Richardson, DR Iyer, O M'Saad, L Zasadil, KA Knouse, ... Developmental Cell 41 (6), 638-651. e5, 2017 | 378 | 2017 |
Single cell sequencing reveals low levels of aneuploidy across mammalian tissues KA Knouse, J Wu, CA Whittaker, A Amon Proceedings of the National Academy of Sciences 111 (37), 13409-13414, 2014 | 343 | 2014 |
TGFβ‐stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro‐migratory TGFβ switch IM Liu, SH Schilling, KA Knouse, L Choy, R Derynck, XF Wang The EMBO Journal 28 (2), 88-98, 2009 | 213 | 2009 |
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease KR Stevens, MA Scull, V Ramanan, CL Fortin, RR Chaturvedi, KA Knouse, ... Science Translational Medicine 9 (399), eaah5505, 2017 | 177 | 2017 |
Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture KA Knouse, KE Lopez, M Bachofner, A Amon Cell 175 (1), 200-211. e13, 2018 | 165 | 2018 |
Assessment of megabase-scale somatic copy number variation using single-cell sequencing KA Knouse, J Wu, A Amon Genome research 26 (3), 376-384, 2016 | 117 | 2016 |
Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution W Leung, CD Shaffer, LK Reed, ST Smith, W Barshop, W Dirkes, ... G3: Genes| Genomes| Genetics 5 (5), 719-740, 2015 | 109 | 2015 |
Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo SJ Pfau, RE Silberman, KA Knouse, A Amon Genes & Development 30 (12), 1395-1408, 2016 | 95 | 2016 |
Aneuploidy in Cancer: Seq-ing Answers to Old Questions KA Knouse, T Davoli, SJ Elledge, A Amon Annual Review of Cancer Biology 1, 335-354, 2017 | 86 | 2017 |
Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential SZ Swartz, LS McKay, KC Su, L Bury, A Padeganeh, PS Maddox, ... Developmental cell 51 (1), 35-48. e7, 2019 | 73 | 2019 |
Genome-scale CRISPR screening in a single mouse liver HR Keys, KA Knouse Cell genomics 2 (12), 2022 | 24 | 2022 |
The micronucleus gets its big break KA Knouse, A Amon Nature 522 (7555), 162-163, 2015 | 12 | 2015 |
Detection of copy number alterations using single cell sequencing KA Knouse, J Wu, A Hendricks JoVE (Journal of Visualized Experiments), e55143, 2017 | 10 | 2017 |
A genome-wide screen in the mouse liver reveals sex-specific and cell non-autonomous regulation of cell fitness HR Keys, KA Knouse bioRxiv, 2021.01. 30.428976, 2021 | 4 | 2021 |
The many sides of CIN KA Knouse, A Amon Nature Reviews Molecular Cell Biology 14 (10), 611-611, 2013 | 4 | 2013 |
Introductions to the Community: Early-Career Researchers in the Time of COVID-19 B Mogessie, K Knouse, A Viny, M Saade, T Toda Elsevier, 2021 | | 2021 |
Tissue Architecture Is Required for Chromosome Segregation Fidelity in Epithelia K Knouse Harvard University, 2018 | | 2018 |
Prevalence and prevention of large-scale somatic copy number alterations KA Knouse Massachusetts Institute of Technology, 2017 | | 2017 |
Temporally and spatially inducible mouse model of aneuploidy D Eichberg, K Knouse, A Amon Cancer Research 74 (19 Supplement), 2429-2429, 2014 | | 2014 |
Hepatocytes maintain their karyotype in spite of being polyploid K Knouse, A Amon Hepatology 60, 813A, 2014 | | 2014 |