| Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN) Nature genetics 40 (2), 204-210, 2008 | 1447 | 2008 |
| Complement C3 activation is required for antiphospholipid antibody-induced fetal loss VM Holers, G Girardi, L Mo, JM Guthridge, H Molina, SS Pierangeli, ... The Journal of experimental medicine 195 (2), 211-220, 2002 | 729 | 2002 |
| Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome CJ Lessard, H Li, I Adrianto, JA Ice, A Rasmussen, KM Grundahl, JA Kelly, ... Nature genetics 45 (11), 1284-1292, 2013 | 555 | 2013 |
| Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 458 | 2010 |
| Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis A Hinks, J Cobb, MC Marion, S Prahalad, M Sudman, J Bowes, P Martin, ... Nature genetics 45 (6), 664-669, 2013 | 449 | 2013 |
| A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus SK Nath, S Han, X Kim-Howard, JA Kelly, P Viswanathan, GS Gilkeson, ... Nature genetics 40 (2), 152-154, 2008 | 360 | 2008 |
| Transancestral mapping and genetic load in systemic lupus erythematosus CD Langefeld, HC Ainsworth, DSC Graham, JA Kelly, ME Comeau, ... Nature communications 8 (1), 16021, 2017 | 343 | 2017 |
| Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways E Der, H Suryawanshi, P Morozov, M Kustagi, B Goilav, S Ranabothu, ... Nature immunology 20 (7), 915-927, 2019 | 316 | 2019 |
| Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus N Shen, Q Fu, Y Deng, X Qian, J Zhao, KM Kaufman, YL Wu, CY Yu, ... Proceedings of the National Academy of Sciences 107 (36), 15838-15843, 2010 | 309 | 2010 |
| Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus LL Ritterhouse, SR Crowe, TB Niewold, DL Kamen, SR Macwana, ... Annals of the rheumatic diseases 70 (9), 1569-1574, 2011 | 303 | 2011 |
| Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus I Adrianto, F Wen, A Templeton, G Wiley, JB King, CJ Lessard, JS Bates, ... Nature genetics 43 (3), 253-258, 2011 | 297 | 2011 |
| Identification of unique microRNA signature associated with lupus nephritis JL Te, IM Dozmorov, JM Guthridge, KL Nguyen, JW Cavett, JA Kelly, ... PloS one 5 (5), e10344, 2010 | 247 | 2010 |
| Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification ME Munroe, R Lu, YD Zhao, DA Fife, JM Robertson, JM Guthridge, ... Annals of the rheumatic diseases 75 (11), 2014-2021, 2016 | 243 | 2016 |
| Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility J Zhao, H Wu, M Khosravi, H Cui, X Qian, JA Kelly, KM Kaufman, ... PLoS genetics 7 (5), e1002079, 2011 | 215 | 2011 |
| Structure of complement receptor 2 in complex with its C3d ligand G Szakonyi, JM Guthridge, D Li, K Young, VM Holers, XS Chen Science 292 (5522), 1725-1728, 2001 | 204 | 2001 |
| Mice deficient in complement receptors 1 and 2 lack a tissue injury-inducing subset of the natural antibody repertoire SD Fleming, T Shea-Donohue, JM Guthridge, L Kulik, TJ Waldschmidt, ... The Journal of Immunology 169 (4), 2126-2133, 2002 | 199 | 2002 |
| Identification of multiple genetic susceptibility loci in Takayasu arteritis G Saruhan-Direskeneli, T Hughes, K Aksu, G Keser, P Coit, SZ Aydin, ... The American Journal of Human Genetics 93 (2), 298-305, 2013 | 198 | 2013 |
| PD-1hiCXCR5–T peripheral helper cells promote B cell responses in lupus via MAF and IL-21 AV Bocharnikov, J Keegan, VS Wacleche, Y Cao, CY Fonseka, G Wang, ... JCI insight 4 (20), 2019 | 187 | 2019 |
| Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study CJ Lessard, I Adrianto, JA Ice, GB Wiley, JA Kelly, SB Glenn, AJ Adler, ... The American Journal of Human Genetics 90 (4), 648-660, 2012 | 184 | 2012 |
| Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies R Lu, ME Munroe, JM Guthridge, KM Bean, DA Fife, H Chen, ... Journal of autoimmunity 74, 182-193, 2016 | 162 | 2016 |
