A core Klf circuitry regulates self-renewal of embryonic stem cells J Jiang, YS Chan, YH Loh, J Cai, GQ Tong, CA Lim, P Robson, S Zhong, ... Nature cell biology 10 (3), 353-360, 2008 | 915 | 2008 |
Transposable elements have rewired the core regulatory network of human embryonic stem cells G Kunarso, NY Chia, J Jeyakani, C Hwang, X Lu, YS Chan, HH Ng, ... Nature genetics 42 (7), 631-634, 2010 | 851 | 2010 |
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb B Feng, J Jiang, P Kraus, JH Ng, JCD Heng, YS Chan, LP Yaw, W Zhang, ... Nature cell biology 11 (2), 197-203, 2009 | 640 | 2009 |
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau, P Kumar, L Yang, ... Nature 468 (7321), 316-320, 2010 | 544 | 2010 |
Induction of a human pluripotent state with distinct regulatory circuitry that resembles preimplantation epiblast YS Chan, J Göke, JH Ng, X Lu, KAU Gonzales, CP Tan, WQ Tng, ZZ Hong, ... Cell stem cell 13 (6), 663-675, 2013 | 439 | 2013 |
Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells J Göke, X Lu, YS Chan, HH Ng, LH Ly, F Sachs, I Szczerbinska Cell stem cell 16 (2), 135-141, 2015 | 342 | 2015 |
In vivo mapping of eukaryotic RNA interactomes reveals principles of higher-order organization and regulation JGA Aw, Y Shen, A Wilm, M Sun, XN Lim, KL Boon, S Tapsin, YS Chan, ... Molecular cell 62 (4), 603-617, 2016 | 317 | 2016 |
Deterministic restriction on pluripotent state dissolution by cell-cycle pathways KAU Gonzales, H Liang, YS Lim, YS Chan, JC Yeo, CP Tan, B Gao, B Le, ... Cell 162 (3), 564-579, 2015 | 228 | 2015 |
ELABELA is an endogenous growth factor that sustains hESC self-renewal via the PI3K/AKT pathway L Ho, SYX Tan, S Wee, Y Wu, SJC Tan, NB Ramakrishna, SC Chng, ... Cell stem cell 17 (4), 435-447, 2015 | 176 | 2015 |
KLF4 and PBX1 Directly Regulate NANOG Expression in Human Embryonic Stem Cells KKK Chan, J Zhang, NY Chia, YS Chan, HS Sim, KS Tan, SKW Oh, ... Stem cells 27 (9), 2114-2125, 2009 | 167 | 2009 |
Human pluripotent stem cell-derived organoids as models of liver disease MNB Ramli, YS Lim, CT Koe, D Demircioglu, W Tng, KAU Gonzales, ... Gastroenterology 159 (4), 1471-1486. e12, 2020 | 160 | 2020 |
Transcriptional regulatory networks in embryonic stem cells YS Chan, L Yang, HH Ng Epigenetics and Disease: Pharmaceutical Opportunities, 239-252, 2011 | 143 | 2011 |
Genome-wide kinase-chromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells J Göke, YS Chan, J Yan, M Vingron, HH Ng Molecular cell 50 (6), 844-855, 2013 | 111 | 2013 |
A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming YS Chan, J Göke, X Lu, N Venkatesan, B Feng, IH Su, HH Ng Stem Cells 31 (4), 682-692, 2013 | 74 | 2013 |
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice Z Her, JHL Tan, YS Lim, SY Tan, XY Chan, WWS Tan, M Liu, KSM Yong, ... Frontiers in immunology 11, 580968, 2020 | 63 | 2020 |
A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines Y Chen, NM Davidson, YK Wan, H Patel, F Yao, HM Low, C Hendra, ... BioRxiv, 2021.04. 21.440736, 2021 | 59 | 2021 |
New high-throughput screening identifies compounds that reduce viability specifically in liver cancer cells that express high levels of SALL4 by inhibiting oxidative … JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ... Gastroenterology 157 (6), 1615-1629. e17, 2019 | 47 | 2019 |
A chemically defined feeder-free system for the establishment and maintenance of the human naive pluripotent state I Szczerbinska, KAU Gonzales, E Cukuroglu, MNB Ramli, BPG Lee, ... Stem Cell Reports 13 (4), 612-626, 2019 | 27 | 2019 |
Emerging liver organoid platforms and technologies DTUH Lam, YY Dan, YS Chan, HH Ng Cell Regeneration 10, 1-19, 2021 | 22 | 2021 |
A chemically well-defined, self-assembling 3D substrate for long-term culture of human pluripotent stem cells Y Loo, YS Chan, I Szczerbinska, BCP Tan, ACA Wan, HH Ng, ... ACS Applied Bio Materials 2 (4), 1406-1412, 2019 | 16 | 2019 |