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Chan Yun Shen
Chan Yun Shen
Principal Investigator, Guangzhou Laboratory, China
Verified email at gzlab.ac.cn - Homepage
Title
Cited by
Cited by
Year
A core Klf circuitry regulates self-renewal of embryonic stem cells
J Jiang, YS Chan, YH Loh, J Cai, GQ Tong, CA Lim, P Robson, S Zhong, ...
Nature cell biology 10 (3), 353-360, 2008
9152008
Transposable elements have rewired the core regulatory network of human embryonic stem cells
G Kunarso, NY Chia, J Jeyakani, C Hwang, X Lu, YS Chan, HH Ng, ...
Nature genetics 42 (7), 631-634, 2010
8512010
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
B Feng, J Jiang, P Kraus, JH Ng, JCD Heng, YS Chan, LP Yaw, W Zhang, ...
Nature cell biology 11 (2), 197-203, 2009
6402009
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau, P Kumar, L Yang, ...
Nature 468 (7321), 316-320, 2010
5442010
Induction of a human pluripotent state with distinct regulatory circuitry that resembles preimplantation epiblast
YS Chan, J Göke, JH Ng, X Lu, KAU Gonzales, CP Tan, WQ Tng, ZZ Hong, ...
Cell stem cell 13 (6), 663-675, 2013
4392013
Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells
J Göke, X Lu, YS Chan, HH Ng, LH Ly, F Sachs, I Szczerbinska
Cell stem cell 16 (2), 135-141, 2015
3422015
In vivo mapping of eukaryotic RNA interactomes reveals principles of higher-order organization and regulation
JGA Aw, Y Shen, A Wilm, M Sun, XN Lim, KL Boon, S Tapsin, YS Chan, ...
Molecular cell 62 (4), 603-617, 2016
3172016
Deterministic restriction on pluripotent state dissolution by cell-cycle pathways
KAU Gonzales, H Liang, YS Lim, YS Chan, JC Yeo, CP Tan, B Gao, B Le, ...
Cell 162 (3), 564-579, 2015
2282015
ELABELA is an endogenous growth factor that sustains hESC self-renewal via the PI3K/AKT pathway
L Ho, SYX Tan, S Wee, Y Wu, SJC Tan, NB Ramakrishna, SC Chng, ...
Cell stem cell 17 (4), 435-447, 2015
1762015
KLF4 and PBX1 Directly Regulate NANOG Expression in Human Embryonic Stem Cells
KKK Chan, J Zhang, NY Chia, YS Chan, HS Sim, KS Tan, SKW Oh, ...
Stem cells 27 (9), 2114-2125, 2009
1672009
Human pluripotent stem cell-derived organoids as models of liver disease
MNB Ramli, YS Lim, CT Koe, D Demircioglu, W Tng, KAU Gonzales, ...
Gastroenterology 159 (4), 1471-1486. e12, 2020
1602020
Transcriptional regulatory networks in embryonic stem cells
YS Chan, L Yang, HH Ng
Epigenetics and Disease: Pharmaceutical Opportunities, 239-252, 2011
1432011
Genome-wide kinase-chromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells
J Göke, YS Chan, J Yan, M Vingron, HH Ng
Molecular cell 50 (6), 844-855, 2013
1112013
A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming
YS Chan, J Göke, X Lu, N Venkatesan, B Feng, IH Su, HH Ng
Stem Cells 31 (4), 682-692, 2013
742013
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Z Her, JHL Tan, YS Lim, SY Tan, XY Chan, WWS Tan, M Liu, KSM Yong, ...
Frontiers in immunology 11, 580968, 2020
632020
A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines
Y Chen, NM Davidson, YK Wan, H Patel, F Yao, HM Low, C Hendra, ...
BioRxiv, 2021.04. 21.440736, 2021
592021
New high-throughput screening identifies compounds that reduce viability specifically in liver cancer cells that express high levels of SALL4 by inhibiting oxidative …
JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ...
Gastroenterology 157 (6), 1615-1629. e17, 2019
472019
A chemically defined feeder-free system for the establishment and maintenance of the human naive pluripotent state
I Szczerbinska, KAU Gonzales, E Cukuroglu, MNB Ramli, BPG Lee, ...
Stem Cell Reports 13 (4), 612-626, 2019
272019
Emerging liver organoid platforms and technologies
DTUH Lam, YY Dan, YS Chan, HH Ng
Cell Regeneration 10, 1-19, 2021
222021
A chemically well-defined, self-assembling 3D substrate for long-term culture of human pluripotent stem cells
Y Loo, YS Chan, I Szczerbinska, BCP Tan, ACA Wan, HH Ng, ...
ACS Applied Bio Materials 2 (4), 1406-1412, 2019
162019
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