| Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells JK Stock, S Giadrossi, M Casanova, E Brookes, M Vidal, H Koseki, ... Nature cell biology 9 (12), 1428-1435, 2007 | 756 | 2007 |
| A comparison of non-integrating reprogramming methods TM Schlaeger, L Daheron, TR Brickler, S Entwisle, K Chan, A Cianci, ... Nature biotechnology 33 (1), 58-63, 2015 | 559 | 2015 |
| Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2 A Kanhere, K Viiri, CC Araújo, J Rasaiyaah, RD Bouwman, WA Whyte, ... Molecular cell 38 (5), 675-688, 2010 | 450 | 2010 |
| Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ... Nature cell biology 12 (6), 618-624, 2010 | 341 | 2010 |
| Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ... Cell stem cell 10 (2), 157-170, 2012 | 317 | 2012 |
| Modifications of RNA polymerase II are pivotal in regulating gene expression states E Brookes, A Pombo EMBO reports 10 (11), 1213-1219, 2009 | 189 | 2009 |
| A histone methylation network regulates transgenerational epigenetic memory in C. elegans EL Greer, SE Beese-Sims, E Brookes, R Spadafora, Y Zhu, SB Rothbart, ... Cell reports 7 (1), 113-126, 2014 | 181 | 2014 |
| Diverse epigenetic mechanisms of human disease E Brookes, Y Shi Annual review of genetics 48, 237-268, 2014 | 151 | 2014 |
| Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment O Alder, F Lavial, A Helness, E Brookes, S Pinho, A Chandrashekran, ... Development 137 (15), 2483-2492, 2010 | 132 | 2010 |
| A mouse model of X-linked intellectual disability associated with impaired removal of histone methylation S Iwase, E Brookes, S Agarwal, AI Badeaux, H Ito, CN Vallianatos, ... Cell reports 14 (5), 1000-1009, 2016 | 122 | 2016 |
| Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity E Brookes, B Laurent, K Õunap, R Carroll, JB Moeschler, M Field, ... Human molecular genetics 24 (10), 2861-2872, 2015 | 74 | 2015 |
| Developmental control of plasma leptin and adipose leptin messenger ribonucleic acid in the ovine fetus during late gestation: role of glucocorticoids and thyroid hormones DM O’Connor, D Blache, N Hoggard, E Brookes, FBP Wooding, ... Endocrinology 148 (8), 3750-3757, 2007 | 48 | 2007 |
| Enhancer SINEs link Pol III to Pol II transcription in neurons C Policarpi, L Crepaldi, E Brookes, J Nitarska, SM French, A Coatti, ... Cell reports 21 (10), 2879-2894, 2017 | 46 | 2017 |
| Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells JD Dias, T Rito, E Torlai Triglia, A Kukalev, C Ferrai, M Chotalia, ... Elife 4, e11215, 2015 | 44 | 2015 |
| An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation P Sabbattini, M Sjoberg, S Nikic, A Frangini, PH Holmqvist, N Kunowska, ... Molecular biology of the cell 25 (6), 904-915, 2014 | 36 | 2014 |
| KDM1A maintains genome-wide homeostasis of transcriptional enhancers S Agarwal, KM Bonefas, PM Garay, E Brookes, Y Murata-Nakamura, ... Genome research 31 (2), 186-197, 2021 | 17 | 2021 |
| Location, location, location: nuclear structure regulates gene expression in neurons E Brookes, A Riccio Current opinion in neurobiology 59, 16-25, 2019 | 10 | 2019 |
| Code breaking: the RNAPII modification code in pluripotency E Brookes, A Pombo Cell cycle 11 (7), 1267-1268, 2012 | 9 | 2012 |
| New insights into intellectual disability caused by mutations in a chromatin regulator E Brookes EBioMedicine 6, 2-3, 2016 | 6 | 2016 |
| A novel enhancer that regulates Bdnf expression in developing neurons E Brookes, HY Alan Au, W Varsally, C Barrington, S Hadjur, A Riccio bioRxiv, 2021.11. 18.469096, 2021 | 2 | 2021 |
