| Dynorphin is a specific endogenous ligand of the κ opioid receptor C Chavkin, IF James, A Goldstein Science 215 (4531), 413-415, 1982 | 1524 | 1982 |
| Regulation of µ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance JT Williams, SL Ingram, G Henderson, C Chavkin, M von Zastrow, ... Pharmacological reviews 65 (1), 223-254, 2013 | 900 | 2013 |
| Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse VM Navarro, ML Gottsch, C Chavkin, H Okamura, DK Clifton, RA Steiner Journal of Neuroscience 29 (38), 11859-11866, 2009 | 830 | 2009 |
| Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus S Impey, M Mark, EC Villacres, S Poser, C Chavkin, DR Storm Neuron 16 (5), 973-982, 1996 | 750 | 1996 |
| The dysphoric component of stress is encoded by activation of the dynorphin κ-opioid system BB Land, MR Bruchas, JC Lemos, M Xu, EJ Melief, C Chavkin Journal of Neuroscience 28 (2), 407-414, 2008 | 699 | 2008 |
| Specific receptor for the opioid peptide dynorphin: structure--activity relationships. C Chavkin, A Goldstein Proceedings of the National Academy of Sciences 78 (10), 6543-6547, 1981 | 627 | 1981 |
| The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors MR Bruchas, BB Land, C Chavkin Brain research 1314, 44-55, 2010 | 580 | 2010 |
| κ opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses JP McLaughlin, M Marton-Popovici, C Chavkin Journal of Neuroscience 23 (13), 5674-5683, 2003 | 579 | 2003 |
| Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP ST Wong, J Athos, XA Figueroa, VV Pineda, ML Schaefer, CC Chavkin, ... Neuron 23 (4), 787-798, 1999 | 579 | 1999 |
| Atrial G protein-activated K+ channel: expression cloning and molecular properties. N Dascal, W Schreibmayer, NF Lim, W Wang, C Chavkin, L DiMagno, ... Proceedings of the National Academy of Sciences 90 (21), 10235-10239, 1993 | 538 | 1993 |
| Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A) KM Crowder, JM Gunther, TA Jones, BD Hale, HZ Zhang, MR Peterson, ... Proceedings of the National Academy of Sciences 96 (26), 15268-15273, 1999 | 494 | 1999 |
| Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. ZL Wu, SA Thomas, EC Villacres, Z Xia, ML Simmons, C Chavkin, ... Proceedings of the National Academy of Sciences 92 (1), 220-224, 1995 | 401 | 1995 |
| Kinase cascades and ligand-directed signaling at the kappa opioid receptor MR Bruchas, C Chavkin Psychopharmacology 210, 137-147, 2010 | 362 | 2010 |
| Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive JC Lemos, MJ Wanat, JS Smith, BAS Reyes, NG Hollon, ... Nature 490 (7420), 402-406, 2012 | 359 | 2012 |
| Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization W Jin, S Brown, JP Roche, C Hsieh, JP Celver, A Kovoor, C Chavkin, ... Journal of Neuroscience 19 (10), 3773-3780, 1999 | 355 | 1999 |
| Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking BB Land, MR Bruchas, S Schattauer, WJ Giardino, M Aita, D Messinger, ... Proceedings of the National Academy of Sciences 106 (45), 19168-19173, 2009 | 346 | 2009 |
| Stress-induced p38 mitogen-activated protein kinase activation mediates κ-opioid-dependent dysphoria MR Bruchas, BB Land, M Aita, M Xu, SK Barot, S Li, C Chavkin Journal of Neuroscience 27 (43), 11614-11623, 2007 | 340 | 2007 |
| Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus JJ Wagner, GW Terman, C Chavkin Nature 363 (6428), 451-454, 1993 | 301 | 1993 |
| Kappa opioid receptor activation of p38 MAPK is GRK3-and arrestin-dependent in neurons and astrocytes MR Bruchas, TA Macey, JD Lowe, C Chavkin Journal of Biological Chemistry 281 (26), 18081-18089, 2006 | 291 | 2006 |
| Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction MR Bruchas, AG Schindler, H Shankar, DI Messinger, M Miyatake, ... Neuron 71 (3), 498-511, 2011 | 288 | 2011 |
