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Faith H. Brennan
Faith H. Brennan
Verified email at queensu.ca - Homepage
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Cited by
Year
The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization
MCL Wu, FH Brennan, JPL Lynch, S Mantovani, S Phipps, RA Wetsel, ...
Proceedings of the National Academy of Sciences 110 (23), 9439-9444, 2013
1702013
Complement activation in the injured central nervous system: another dual-edged sword?
FH Brennan, AJ Anderson, SM Taylor, TM Woodruff, MJ Ruitenberg
Journal of neuroinflammation 9, 1-13, 2012
1492012
The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury
FH Brennan, R Gordon, HW Lao, PJ Biggins, SM Taylor, RJM Franklin, ...
Journal of Neuroscience 35 (16), 6517-6531, 2015
1252015
Mobilisation of the splenic monocyte reservoir and peripheral CX3CR1 deficiency adversely affects recovery from spinal cord injury
LV Blomster, FH Brennan, HW Lao, DW Harle, AR Harvey, MJ Ruitenberg
Experimental neurology 247, 226-240, 2013
1132013
Microglia coordinate cellular interactions during spinal cord repair in mice
FH Brennan, Y Li, C Wang, A Ma, Q Guo, Y Li, N Pukos, WA Campbell, ...
Nature communications 13 (1), 4096, 2022
1002022
Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2
FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, ...
JCI insight 4 (9), 2019
842019
Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions
FH Brennan, JD Lee, MJ Ruitenberg, TM Woodruff
Seminars in Immunology 28 (3), 292-308, 2016
752016
Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury
FH Brennan, PG Popovich
Current opinion in neurology 31 (3), 334-344, 2018
712018
The spleen as a neuroimmune interface after spinal cord injury
BT Noble, FH Brennan, PG Popovich
Journal of neuroimmunology 321, 1-11, 2018
692018
Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4 T) in vivo diffusion tensor imaging
FH Brennan, GJ Cowin, ND Kurniawan, MJ Ruitenberg
Neuroimage 82, 574-585, 2013
682013
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model
PC Low, S Manzanero, N Mohannak, VK Narayana, TH Nguyen, ...
Nature communications 5 (1), 1-12, 2014
632014
Spinal cord injury causes chronic bone marrow failure
RS Carpenter, JM Marbourg, FH Brennan, KA Mifflin, JCE Hall, RR Jiang, ...
Nature communications 11 (1), 3702, 2020
432020
The alternative receptor for complement component 5a, C5aR2, conveys neuroprotection in traumatic spinal cord injury
PJC Biggins, FH Brennan, SM Taylor, TM Woodruff, MJ Ruitenberg
Journal of Neurotrauma 34 (12), 2075-2085, 2017
422017
Microglia maintain the normal structure and function of the hippocampal astrocyte network
Y Du, FH Brennan, PG Popovich, M Zhou
Glia 70 (7), 1359-1379, 2022
412022
IRIS3: integrated cell-type-specific regulon inference server from single-cell RNA-Seq
A Ma, C Wang, Y Chang, FH Brennan, A McDermaid, B Liu, C Zhang, ...
Nucleic acids research 48 (W1), W275-W286, 2020
372020
Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury
FH Brennan, BT Noble, Y Wang, Z Guan, H Davis, X Mo, C Harris, ...
Cell reports 34 (4), 2021
332021
IVIg attenuates complement and improves spinal cord injury outcomes in mice
FH Brennan, ND Kurniawan, J Vukovic, PF Bartlett, F Käsermann, ...
Annals of Clinical and Translational Neurology 3 (7), 495-511, 2016
322016
Serial systemic injections of endotoxin (LPS) elicit neuroprotective spinal cord microglia through IL-1-dependent cross talk with endothelial cells
CM Freria, FH Brennan, DR Sweet, Z Guan, JC Hall, KA Kigerl, ...
Journal of Neuroscience 40 (47), 9103-9120, 2020
242020
Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice
RS Carpenter, RR Jiang, FH Brennan, JCE Hall, MK Gottipati, S Niewiesk, ...
Scientific reports 9 (1), 19105, 2019
182019
Thoracic VGluT2+ Spinal interneurons regulate structural and functional plasticity of sympathetic networks after high-level spinal cord injury
BT Noble, FH Brennan, Y Wang, Z Guan, X Mo, JM Schwab, PG Popovich
Journal of Neuroscience 42 (17), 3659-3675, 2022
172022
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